BS7448

antibody from Bioworld Technology, Inc
Targeting: CXCR2 CD182, CMKAR2, IL8RB
Provider product page for BS7448

Antibody data

Product number
BS7448 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CXCR2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human CXCR2.
Description
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CXCR2 protein structure - BS7448 shown in red.