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- Antibody Data
- Antigen structure
- References [3]
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- Flow cytometry [1]
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- Product number
- MAB1850 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB1850, RRID:AB_1678511
- Product name
- CXCR2 monoclonal antibody, clone 19
- Antibody type
- Monoclonal
- Antigen
- A synthetic peptide corresponding to amino acids 1-19 of human CXCR2.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 100 µg
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Expression and functional activity of the IL-8 receptor type CXCR1 and CXCR2 on human mast cells.
Differential usage of the CXC chemokine receptors 1 and 2 by interleukin-8, granulocyte chemotactic protein-2 and epithelial-cell-derived neutrophil attractant-78.
Granulocyte chemotactic protein 2 acts via both IL-8 receptors, CXCR1 and CXCR2.
Lippert U, Artuc M, Grützkau A, Möller A, Kenderessy-Szabo A, Schadendorf D, Norgauer J, Hartmann K, Schweitzer-Stenner R, Zuberbier T, Henz BM, Krüger-Krasagakes S
Journal of immunology (Baltimore, Md. : 1950) 1998 Sep 1;161(5):2600-8
Journal of immunology (Baltimore, Md. : 1950) 1998 Sep 1;161(5):2600-8
Differential usage of the CXC chemokine receptors 1 and 2 by interleukin-8, granulocyte chemotactic protein-2 and epithelial-cell-derived neutrophil attractant-78.
Wuyts A, Proost P, Lenaerts JP, Ben-Baruch A, Van Damme J, Wang JM
European journal of biochemistry / FEBS 1998 Jul 1;255(1):67-73
European journal of biochemistry / FEBS 1998 Jul 1;255(1):67-73
Granulocyte chemotactic protein 2 acts via both IL-8 receptors, CXCR1 and CXCR2.
Wolf M, Delgado MB, Jones SA, Dewald B, Clark-Lewis I, Baggiolini M
European journal of immunology 1998 Jan;28(1):164-70
European journal of immunology 1998 Jan;28(1):164-70
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Isolated human neutrophils were incubated with 1.0 ug CXCR2 monoclonal antibody, clone 19 (Cat # MAB1850) followed by staining with goat F (ab') 2 anti-mouse IgG FITC [ shaded peak ] . Specificity of signal was confirmed by staining the neutrophils with 1.0 ug mouse IgG1 isotype control followed by the secondary antibody [ unshaded peak ] . The data indicate that approximately 98% of the isolated neutrophil population stains positive for this CXCR2 (M2 region).
- Validation comment
- Flow Cytometry
