HPAB-0306-YC

antibody from Creative Biolabs

Targeting: CXCR2 CD182, CMKAR2, IL8RB

ELISA (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

HPAB-0306-YC

Provider

Creative Biolabs

Product name

Human Anti-CXCR2 Recombinant Antibody (clone HY29)

Antibody type

Monoclonal

Description

An isolated antibody (HY29) specifically binds to CXC chemokine receptor-2 (CXCR2), wherein the binding molecule can inhibit binding to interleukin 8 (IL-8). Mapping of the N terminus using linear peptides and alanine scanning of CLIPS peptides derived from the N terminus and ECL3 showed that the minimal epitope for the antibody binding was centered around the 31 PFLLD 35 with the second leucine and the aspartic acid key to the binding interaction.

Reactivity

Human, Mouse, Simian

Host

Human

Epitope

Binding around the 31 PFLLD 35 with the second leucine and the aspartic acid key to the binding interaction

Antibody clone number

HY29

Storage

Centrifuge briefly prior to opening vial. Store at +4¡ãC short term (1-2 weeks). Aliquot and store at -20¡ãC long term. Avoid repeated freeze/thaw cycles.