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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [6]
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- Product number
- ABIN967402 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Recombination Activating Gene 1 (RAG1) antibody
- Antibody type
- Monoclonal
- Antigen
- Recombinant Human Rag-1
- Description
- Purified from tissue culture supernatant or ascites by affinity chromatography.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- G189-1417
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- 4°C
Submitted references rag-1 and rag-2 are components of a high-molecular-weight complex, and association of rag-2 with this complex is rag-1 dependent.
Dispensable sequence motifs in the RAG-1 and RAG-2 genes for plasmid V(D)J recombination.
RAG-1-deficient mice have no mature B and T lymphocytes.
RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement.
The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system.
RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination.
Leu TM, Schatz DG
Molecular and cellular biology 1995 Oct;15(10):5657-70
Molecular and cellular biology 1995 Oct;15(10):5657-70
Dispensable sequence motifs in the RAG-1 and RAG-2 genes for plasmid V(D)J recombination.
Silver DP, Spanopoulou E, Mulligan RC, Baltimore D
Proceedings of the National Academy of Sciences of the United States of America 1993 Jul 1;90(13):6100-4
Proceedings of the National Academy of Sciences of the United States of America 1993 Jul 1;90(13):6100-4
RAG-1-deficient mice have no mature B and T lymphocytes.
Mombaerts P, Iacomini J, Johnson RS, Herrup K, Tonegawa S, Papaioannou VE
Cell 1992 Mar 6;68(5):869-77
Cell 1992 Mar 6;68(5):869-77
RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement.
Shinkai Y, Rathbun G, Lam KP, Oltz EM, Stewart V, Mendelsohn M, Charron J, Datta M, Young F, Stall AM
Cell 1992 Mar 6;68(5):855-67
Cell 1992 Mar 6;68(5):855-67
The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system.
Chun JJ, Schatz DG, Oettinger MA, Jaenisch R, Baltimore D
Cell 1991 Jan 11;64(1):189-200
Cell 1991 Jan 11;64(1):189-200
RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination.
Oettinger MA, Schatz DG, Gorka C, Baltimore D
Science (New York, N.Y.) 1990 Jun 22;248(4962):1517-23
Science (New York, N.Y.) 1990 Jun 22;248(4962):1517-23
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