Antibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
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- Product number
- ABIN359095 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- N-Term
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Regulation of kinase activity of 3-phosphoinositide-dependent protein kinase-1 by binding to 14-3-3.
A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation.
Sphingosine is a novel activator of 3-phosphoinositide-dependent kinase 1.
Sato S, Fujita N, Tsuruo T
The Journal of biological chemistry 2002 Oct 18;277(42):39360-7
The Journal of biological chemistry 2002 Oct 18;277(42):39360-7
A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation.
Frödin M, Antal TL, Dümmler BA, Jensen CJ, Deak M, Gammeltoft S, Biondi RM
The EMBO journal 2002 Oct 15;21(20):5396-407
The EMBO journal 2002 Oct 15;21(20):5396-407
Sphingosine is a novel activator of 3-phosphoinositide-dependent kinase 1.
King CC, Zenke FT, Dawson PE, Dutil EM, Newton AC, Hemmings BA, Bokoch GM
The Journal of biological chemistry 2000 Jun 16;275(24):18108-13
The Journal of biological chemistry 2000 Jun 16;275(24):18108-13
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