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- Product number
- ABIN969347 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) antibody
- Antibody type
- Monoclonal
- Description
- Ascites
- Reactivity
- Human, Rat, Simian
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 4A11
- Vial size
- 100 μL
- Storage
- 4°C, -20°C for long term storage
Submitted references PDK1 regulates cancer cell motility by antagonising inhibition of ROCK1 by RhoE.
Potentiation of antileukemic therapies by the dual PI3K/PDK-1 inhibitor, BAG956: effects on BCR-ABL- and mutant FLT3-expressing cells.
3-Phosphoinositide-dependent PDK1 negatively regulates transforming growth factor-beta-induced signaling in a kinase-dependent manner through physical interaction with Smad proteins.
Pinner S, Sahai E
Nature cell biology 2008 Feb;10(2):127-37
Nature cell biology 2008 Feb;10(2):127-37
Potentiation of antileukemic therapies by the dual PI3K/PDK-1 inhibitor, BAG956: effects on BCR-ABL- and mutant FLT3-expressing cells.
Weisberg E, Banerji L, Wright RD, Barrett R, Ray A, Moreno D, Catley L, Jiang J, Hall-Meyers E, Sauveur-Michel M, Stone R, Galinsky I, Fox E, Kung AL, Griffin JD
Blood 2008 Apr 1;111(7):3723-34
Blood 2008 Apr 1;111(7):3723-34
3-Phosphoinositide-dependent PDK1 negatively regulates transforming growth factor-beta-induced signaling in a kinase-dependent manner through physical interaction with Smad proteins.
Seong HA, Jung H, Kim KT, Ha H
The Journal of biological chemistry 2007 Apr 20;282(16):12272-89
The Journal of biological chemistry 2007 Apr 20;282(16):12272-89
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