Ab088801

antibody from Aladdin Scientific Corporation

Targeting: ANGPT2 Ang2

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

Ab088801

Provider

Aladdin Scientific Corporation

Product name

ANGPT2 Antibody

Antibody type

Polyclonal

Description

Rabbit anti Human ANGPT2 Antibody, Polyclonal antibody, could be used for WB, IHC and so on.ApplicationWB: 0.2-2µg/mLIHC: 5-20µg/mLProtein FunctionCan induce tyrosine phosphorylation of TIE2. Binds to TIE2 receptor and counteracts blood vessel maturation/stability mediated by angiopoietin-1. Its function may be context-dependent. In the absence of angiogenic inducers, such as VEGF, ANG2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

AA 24-165


Vial size

100μl,10μl,1ml,20μl,50μl

Concentration

Lot by Lot

Storage

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.