Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS7504 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- PTN polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human PTN.
- Description
- Pleiotrophin?(PTN) also known as?heparin-binding brain mitogen?(HBBM) or?heparin-binding growth factor 8?(HBGF-8) or?neurite growth-promoting factor 1?(NEGF1) or?heparin affinity regulatory peptide?(HARP) or?heparin binding growth associated molecule?(HB-GAM) is a?protein?that in humans is encoded by the?PTNgene.?Pleiotrophin is an 18-kDa?growth factor?that has a high affinity for?heparin. It is structurally related to?midkine?and?retinoic acid induced heparin-binding protein. Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot analysis of PTN polyclonal antibody