313305

antibody from BioLegend
Targeting: FLT3 CD135, FLK2, STK1
Provider product page for 313305

Antibody data

Product number
313305 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#313305, RRID:AB_314990
Product name
PE anti-human CD135 (Flt-3/Flk-2)
Antibody type
Monoclonal
Antigen
BV-173 pro-B cell line
Description
CD135 is a 130-160 type III tyrosine kinase receptor expressed on CD34+ hematopoietic stem cells, myelomonocytic progenitors, primitive B cell progenitors, and thymocytes. CD135 is also expressed on malignant hematopoietic cells including AML, ALL and CML-BC. CD135, also known as FMS-like tyrosine kinase-3, FLT3, STK-1, and Flk-2, is a growth factor receptor that binds the FLT3 ligand to promote the growth and differentiation of primitive hematopoietic cells. The intracytoplasmic domain of CD135 is modified by phosphorylation and has been shown to interact with Grb2, SOCS1, VAV1, and Shc.
Reactivity
Human
Host
Mouse
Conjugate
Yellow dye
Isotype
IgG
Vial size
25 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
FLT3 protein structure - 313305 shown in red.