AF812

antibody from R&D Systems

Targeting: FLT3 CD135, FLK2, STK1

Western blot (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

AF812

Provider

R&D Systems

Product name

Human Flt-3/Flk-2 Antibody

Antibody type

Polyclonal

Description

Immunogen affinity purified. Detects human Flt-3/Flk-2 in direct ELISAs and Western blots. In direct ELISAs, approximately 35% cross-reactivity with recombinant mouse Flt-3 is observed.

Reactivity

Human

Host

Goat

Conjugate

Unconjugated

Antigen sequence

AAA18947


Isotype

IgG

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

Soluble phosphorylated fms-like tyrosine kinase III. FLT3 protein in patients with acute myeloid leukemia (AML).

Ravandi F, Jilani I, Estey E, Kantarjian H, Dey A, Aguilar C, Jitkaroon C, Giles F, O'Brien S, Keating M, Albitar M
Leukemia research 2007 Jun;31(6):791-7

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Inhibition of FLT3 in MLL. Validation of a therapeutic target identified by gene expression based classification.

Armstrong SA, Kung AL, Mabon ME, Silverman LB, Stam RW, Den Boer ML, Pieters R, Kersey JH, Sallan SE, Fletcher JA, Golub TR, Griffin JD, Korsmeyer SJ
Cancer cell 2003 Feb;3(2):173-83

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Inhibition of FLT3 in MLL. Validation of a therapeutic target identified by gene expression based classification.

Armstrong SA, Kung AL, Mabon ME, Silverman LB, Stam RW, Den Boer ML, Pieters R, Kersey JH, Sallan SE, Fletcher JA, Golub TR, Griffin JD, Korsmeyer SJ
Cancer cell 2003 Feb;3(2):173-83