STJ22865

antibody from St John's Laboratory

Targeting: CALM1 CALML2, CAMI, DD132, PHKD

Antibody data

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Validation data

Product number: STJ22865 - Provider product page
Provider: St John's Laboratory
Product name: CALM3 antibody
Antibody type: Polyclonal
Description: Calmodulin is a ubiquitously expressed small protein mediating many cellular effects such as short-term and long-term memory, nerve growth, inflammation, apoptosis, muscle contraction and intracellular movement (1). Upon binding of four Ca2+ ions, calmodulin undergoes conformational changes, allowing this complex to bind to and activate many enzymes including protein kinases, protein phosphatases, ion channels, Ca2+ pumps, nitric oxide synthase, inositol triphosphate kinase, and cyclic nucleotide phosphodiesterase (2,3). Since calmodulin binds Ca2+ in a cooperative fashion, small changes in cytosolic Ca2+ levels lead to large changes in the level of active calmodulin and its target proteins (4).
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Concentration: 1 mg/ml
Storage: Store at -20°C. Avoid repeated freeze/thaw cycles.

CALM1 protein structure - STJ22865 shown in red.