BS8632

antibody from Bioworld Technology, Inc
Targeting: SSX2 CT5.2a, HD21, HOM-MEL-40, MGC119055, MGC15364, MGC3884, SSX
Provider product page for BS8632
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8632 - Provider product page
Provider
Bioworld Technology, Inc
Product name
SSX2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Protein SSX2; Cancer/testis antigen 5.2; CT5.2; Synovial sarcoma, X breakpoint 2; Tumor antigen HOM-MEL-40; SSX2; Synonyms:SSX2A; SSX2B
Description
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 727837, located about 45 kb downstream in the opposite orientation on chromosome X.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SSX2 protein structure - BS8632 shown in red.