A00310-1

antibody from Boster Biological Technology
Targeting: KCNQ1 JLNS1, KCNA8, KCNA9, Kv7.1, KVLQT1, LQT, LQT1
Provider product page for A00310-1
Western blot

Antibody data

Product number
A00310-1 - Provider product page
Provider
Boster Biological Technology
Product name
Anti-KCNQ1 Antibody Picoband™
Antibody type
Polyclonal
Description
Polyclonal antibody for KCNQ1 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB. Reactive species: Human. KCNQ1 information: Molecular Weight: 74699 MW; Subcellular Localization: Cell membrane ; Multi- pass membrane protein . Cytoplasmic vesicle membrane . Early endosome . Membrane raft . Endoplasmic reticulum . Basolateral cell membrane . Colocalized with KCNE3 at the plasma membrane (PubMed:10646604). Upon 17beta-oestradiol treatment, colocalizes with RAB5A at early endosome (PubMed:23529131). Heterotetramer with KCNQ5 is highly retained at the endoplasmic reticulum and is localized outside of lipid raft microdomains (PubMed:24855057). During the early stages of epithelial cell polarization induced by the calcium switch it removed from plasma membrane to the endoplasmic reticulum where it retained and it is redistributed to the basolateral cell surface in a PI3K-dependent manner at a later stage (PubMed:21228319); Tissue Specificity: Abundantly expressed in heart, pancreas, prostate, kidney, small intestine and peripheral blood leukocytes. Less abundant in placenta, lung, spleen, colon, thymus, testis and ovaries.
Reactivity
Human, Rat
Host
Rabbit
Vial size
100μg/vial
Concentration
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage
At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Handling
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
KCNQ1 protein structure - A00310-1 shown in red.