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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB2581 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2581, RRID:AB_1571045
- Product name
- AKR1B1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of AKR1B1.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Identification of multiple and distinct defects in prostaglandin biosynthetic pathways in eutopic and ectopic endometrium of women with endometriosis.
Upregulation of aldose reductase during foam cell formation as possible link among diabetes, hyperlipidemia, and atherosclerosis.
Merging the binding sites of aldose and aldehyde reductase for detection of inhibitor selectivity-determining features.
Cloning and prokaryotic expression of a biologically active human placental aldose reductase.
Cloning and prokaryotic expression of a biologically active human placental aldose reductase.
Rakhila H, Carli C, Daris M, Lemyre M, Leboeuf M, Akoum A
Fertility and sterility 2013 Dec;100(6):1650-9.e1-2
Fertility and sterility 2013 Dec;100(6):1650-9.e1-2
Upregulation of aldose reductase during foam cell formation as possible link among diabetes, hyperlipidemia, and atherosclerosis.
Gleissner CA, Sanders JM, Nadler J, Ley K
Arteriosclerosis, thrombosis, and vascular biology 2008 Jun;28(6):1137-43
Arteriosclerosis, thrombosis, and vascular biology 2008 Jun;28(6):1137-43
Merging the binding sites of aldose and aldehyde reductase for detection of inhibitor selectivity-determining features.
Steuber H, Heine A, Podjarny A, Klebe G
Journal of molecular biology 2008 Jun 20;379(5):991-1016
Journal of molecular biology 2008 Jun 20;379(5):991-1016
Cloning and prokaryotic expression of a biologically active human placental aldose reductase.
Grundmann U, Bohn H, Obermeier R, Amann E
DNA and cell biology 1990 Apr;9(3):149-57
DNA and cell biology 1990 Apr;9(3):149-57
Cloning and prokaryotic expression of a biologically active human placental aldose reductase.
Grundmann U, Bohn H, Obermeier R, Amann E
DNA and cell biology 1990 Apr;9(3):149-57
DNA and cell biology 1990 Apr;9(3):149-57
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of AKR1B1 polyclonal antibody (Cat # PAB2581) in A-375 cell line lysates (35 ug/lane).AKR1B1 (arrow) was detected using the purified polyclonal antibody.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with AKR1B1 polyclonal antibody (Cat # PAB2581) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
