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Functional assayAntibody data
- Antibody Data
- Antigen structure
- References [12]
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- Product number
- V2889 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- TGF-beta Antibody
- Antibody type
- Monoclonal
- Antigen
- Bovine TGF-beta2 protein was used as the immunogen for the TGF-beta antibody.
- Description
- Protein G purified antibody
- Reactivity
- Human, Mouse, Rat, Bovine, Canine, Simian
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- 1D11.16.8
- Vial size
- 20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)
- Storage
- Store the TGF-beta antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references TGF-β Blockade Reduces Mortality and Metabolic Changes in a Validated Murine Model of Pancreatic Cancer Cachexia.
Immunosuppressive and Prometastatic Functions of Myeloid-Derived Suppressive Cells Rely upon Education from Tumor-Associated B Cells.
Intratumoral administration of mRNA encoding a fusokine consisting of IFN-β and the ectodomain of the TGF-β receptor II potentiates antitumor immunity.
Androgens contribute to sex differences in myocardial remodeling under pressure overload by a mechanism involving TGF-β.
TGF-β blockade does not improve control of an established persistent viral infection.
Helminth protection against autoimmune diabetes in nonobese diabetic mice is independent of a type 2 immune shift and requires TGF-β.
Bystander-mediated stimulation of proteolipid protein-specific regulatory T (Treg) cells confers protection against experimental autoimmune encephalomyelitis (EAE) via TGF-β
Segregated regulatory CD39+CD4+ T cell function: TGF-β-producing Foxp3- and IL-10-producing Foxp3+ cells are interdependent for protection against collagen-induced arthritis.
Heterologous T cells can help restore function in dysfunctional hepatitis C virus nonstructural 3/4A-specific T cells during therapeutic vaccination.
Development of tumor-infiltrating CD8+ T cell memory precursor effector cells and antimelanoma memory responses are the result of vaccination and TGF-β blockade during the perioperative period of tumor resection.
Nonredundant roles of IL-10 and TGF-β in suppression of immune responses to hepatic AAV-factor IX gene transfer.
IL-12p35 promotes antibody-induced joint inflammation by activating NKT cells and suppressing TGF-beta.
Greco SH, Tomkötter L, Vahle AK, Rokosh R, Avanzi A, Mahmood SK, Deutsch M, Alothman S, Alqunaibit D, Ochi A, Zambirinis C, Mohaimin T, Rendon M, Levie E, Pansari M, Torres-Hernandez A, Daley D, Barilla R, Pachter HL, Tippens D, Malik H, Boutajangout A, Wisniewski T, Miller G
PloS one 2015;10(7):e0132786
PloS one 2015;10(7):e0132786
Immunosuppressive and Prometastatic Functions of Myeloid-Derived Suppressive Cells Rely upon Education from Tumor-Associated B Cells.
Bodogai M, Moritoh K, Lee-Chang C, Hollander CM, Sherman-Baust CA, Wersto RP, Araki Y, Miyoshi I, Yang L, Trinchieri G, Biragyn A
Cancer research 2015 Sep 1;75(17):3456-65
Cancer research 2015 Sep 1;75(17):3456-65
Intratumoral administration of mRNA encoding a fusokine consisting of IFN-β and the ectodomain of the TGF-β receptor II potentiates antitumor immunity.
Van der Jeught K, Joe PT, Bialkowski L, Heirman C, Daszkiewicz L, Liechtenstein T, Escors D, Thielemans K, Breckpot K
Oncotarget 2014 Oct 30;5(20):10100-13
Oncotarget 2014 Oct 30;5(20):10100-13
Androgens contribute to sex differences in myocardial remodeling under pressure overload by a mechanism involving TGF-β.
Montalvo C, Villar AV, Merino D, García R, Ares M, Llano M, Cobo M, Hurlé MA, Nistal JF
PloS one 2012;7(4):e35635
PloS one 2012;7(4):e35635
TGF-β blockade does not improve control of an established persistent viral infection.
Boettler T, Cheng Y, Ehrhardt K, von Herrath M
Viral immunology 2012 Jun;25(3):232-8
Viral immunology 2012 Jun;25(3):232-8
Helminth protection against autoimmune diabetes in nonobese diabetic mice is independent of a type 2 immune shift and requires TGF-β.
Hübner MP, Shi Y, Torrero MN, Mueller E, Larson D, Soloviova K, Gondorf F, Hoerauf A, Killoran KE, Stocker JT, Davies SJ, Tarbell KV, Mitre E
Journal of immunology (Baltimore, Md. : 1950) 2012 Jan 15;188(2):559-68
Journal of immunology (Baltimore, Md. : 1950) 2012 Jan 15;188(2):559-68
Bystander-mediated stimulation of proteolipid protein-specific regulatory T (Treg) cells confers protection against experimental autoimmune encephalomyelitis (EAE) via TGF-β
Jun S, Ochoa-Repáraz J, Zlotkowska D, Hoyt T, Pascual D
Journal of Neuroimmunology 2012 April;245(1-2):39-47
Journal of Neuroimmunology 2012 April;245(1-2):39-47
Segregated regulatory CD39+CD4+ T cell function: TGF-β-producing Foxp3- and IL-10-producing Foxp3+ cells are interdependent for protection against collagen-induced arthritis.
Kochetkova I, Thornburg T, Callis G, Pascual DW
Journal of immunology (Baltimore, Md. : 1950) 2011 Nov 1;187(9):4654-66
Journal of immunology (Baltimore, Md. : 1950) 2011 Nov 1;187(9):4654-66
Heterologous T cells can help restore function in dysfunctional hepatitis C virus nonstructural 3/4A-specific T cells during therapeutic vaccination.
Chen A, Ahlén G, Brenndörfer ED, Brass A, Holmström F, Chen M, Söderholm J, Milich DR, Frelin L, Sällberg M
Journal of immunology (Baltimore, Md. : 1950) 2011 May 1;186(9):5107-18
Journal of immunology (Baltimore, Md. : 1950) 2011 May 1;186(9):5107-18
Development of tumor-infiltrating CD8+ T cell memory precursor effector cells and antimelanoma memory responses are the result of vaccination and TGF-β blockade during the perioperative period of tumor resection.
Bellavance EC, Kohlhapp FJ, Zloza A, O'Sullivan JA, McCracken J, Jagoda MC, Lacek AT, Posner MC, Guevara-Patino JA
Journal of immunology (Baltimore, Md. : 1950) 2011 Mar 15;186(6):3309-16
Journal of immunology (Baltimore, Md. : 1950) 2011 Mar 15;186(6):3309-16
Nonredundant roles of IL-10 and TGF-β in suppression of immune responses to hepatic AAV-factor IX gene transfer.
Hoffman BE, Martino AT, Sack BK, Cao O, Liao G, Terhorst C, Herzog RW
Molecular therapy : the journal of the American Society of Gene Therapy 2011 Jul;19(7):1263-72
Molecular therapy : the journal of the American Society of Gene Therapy 2011 Jul;19(7):1263-72
IL-12p35 promotes antibody-induced joint inflammation by activating NKT cells and suppressing TGF-beta.
Park Y, Kim HS, Ahn JY, Yun D, Cho ML, Hong S, Kim HY, Chung DH
Journal of immunology (Baltimore, Md. : 1950) 2010 Aug 1;185(3):1476-84
Journal of immunology (Baltimore, Md. : 1950) 2010 Aug 1;185(3):1476-84
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