Antibody data
- Antibody Data
- Antigen structure
- References [62]
- Comments [0]
- Validations
- Immunohistochemistry [1]
Submit
Validation data
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- Product number
- 18978-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18978-1-AP, RRID:AB_11182379
- Product name
- TGF Beta 1 antibody
- Antibody type
- Polyclonal
- Description
- TGF Beta 1 antibody (Cat. #18978-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Interleukin-24 protects against liver injury in mouse models.
Exercise reduces hyperlipidemia-induced kidney damage in apolipoprotein E-deficient mice.
Myeloid NEMO deficiency promotes tumor immunosuppression partly via MCP1-CCR2 axis.
The Effect of Lecithins Coupled Decorin Nanoliposomes on Treatment of Carbon Tetrachloride-Induced Liver Fibrosis.
RUNX3-dependent oxidative epithelial-to-mesenchymal transition in methamphetamine-induced chronic lung injury.
Alda-1, an Aldehyde Dehydrogenase 2 Agonist, Improves Cutaneous Wound Healing by Activating Epidermal Keratinocytes via Akt/GSK-3β/β-Catenin Pathway.
Preclinical Evaluation of the Novel Small-Molecule MSI-N1014 for Treating Drug-Resistant Colon Cancer via the LGR5/β-catenin/miR-142-3p Network and Reducing Cancer-Associated Fibroblast Transformation.
Elk-1 transcriptionally regulates ZC3H4 expression to promote silica-induced epithelial-mesenchymal transition.
FOXO4-DRI alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice.
Inhibitory Effect of Corilagin on miR-21-Regulated Hepatic Fibrosis Signaling Pathway.
A small molecule inhibitor MCC950 ameliorates kidney injury in diabetic nephropathy by inhibiting NLRP3 inflammasome activation.
Aloe-Emodin Ameliorates Renal Fibrosis Via Inhibiting PI3K/Akt/mTOR Signaling Pathway In Vivo and In Vitro.
Progressive Degeneration and Inhibition of Peripheral Nerve Regeneration in the SOD1-G93A Mouse Model of Amyotrophic Lateral Sclerosis.
Thioredoxin-interacting protein deficiency ameliorates kidney inflammation and fibrosis in mice with unilateral ureteral obstruction.
miR-663a inhibits tumor growth and invasion by regulating TGF-β1 in hepatocellular carcinoma.
CD103+CD8+ T lymphocytes in non-small cell lung cancer are phenotypically and functionally primed to respond to PD-1 blockade.
Slit2-Robo2 signaling modulates the fibrogenic activity and migration of hepatic stellate cells.
Modulation of TGF‑β activity by latent TGF‑β‑binding protein 1 in human osteoarthritis fibroblast‑like synoviocytes.
Effects of Ovariectomy in an hSOD1-G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis (ALS).
Proefferocytic Therapy Promotes Transforming Growth Factor-β Signaling and Prevents Aneurysm Formation.
AGR2 promotes the proliferation, migration and regulates epithelial-mesenchymal transition in salivary adenoid cystic carcinoma.
Deletion of diacylglycerol-responsive TRPC genes attenuates diabetic nephropathy by inhibiting activation of the TGFβ1 signaling pathway.
Treadmill Exercise Exerts Neuroprotection and Regulates Microglial Polarization and Oxidative Stress in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer's Disease.
Sphingosine kinase 1 protects renal tubular epithelial cells from renal fibrosis via induction of autophagy.
Inhibition of airway remodeling and inflammation by isoforskolin in PDGF-induced rat ASMCs and OVA-induced rat asthma model.
Luteolin-7-diglucuronide attenuates isoproterenol-induced myocardial injury and fibrosis in mice.
Effects of exogenous thymosin β4 on carbon tetrachloride-induced liver injury and fibrosis.
Expression of fibrosis-related molecules in the oral mucosa of six animal species: A reference for selecting animal models.
Oncogenic Kras drives invasion and maintains metastases in colorectal cancer.
Effects of polysaccharide from Physalis alkekengi var. francheti on liver injury and intestinal microflora in type-2 diabetic mice.
Neuronal zinc-α2-glycoprotein is decreased in temporal lobe epilepsy in patients and rats.
Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway.
Pancreatic Kininogenase Ameliorates Renal Fibrosis in Streptozotocin Induced-Diabetic Nephropathy Rat.
Mixed Aqueous Extract of Salvia Miltiorrhiza Reduces Blood Pressure through Inhibition of Vascular Remodelling and Oxidative Stress in Spontaneously Hypertensive Rats.
Naringenin Ameliorated Kidney Injury through Let-7a/TGFBR1 Signaling in Diabetic Nephropathy.
Overexpression of Prolyl-4-Hydroxylase-α1 Stabilizes but Increases Shear Stress-Induced Atherosclerotic Plaque in Apolipoprotein E-Deficient Mice.
Co-expression of LASS2 and TGF-β1 predicts poor prognosis in hepatocellular carcinoma.
Usp2-69 overexpression slows down the progression of rat anti-Thy1.1 nephritis.
Regulation of a TGF-β1-CD147 self-sustaining network in the differentiation plasticity of hepatocellular carcinoma cells.
scAAV9-VEGF prolongs the survival of transgenic ALS mice by promoting activation of M2 microglia and the PI3K/Akt pathway.
Tanshinone IIA attenuates epithelial-mesenchymal transition to inhibit the tracheal narrowing.
Impaired T cell function in malignant pleural effusion is caused by TGF-β derived predominantly from macrophages.
Mitochondria-targeted peptide SS-31 attenuates renal injury via an antioxidant effect in diabetic nephropathy.
Deletion of interleukin-6 alleviated interstitial fibrosis in streptozotocin-induced diabetic cardiomyopathy of mice through affecting TGFβ1 and miR-29 pathways.
Carboxy-terminal modulator protein attenuated extracellular matrix deposit by inhibiting phospho-Akt, TGF-β1 and α-SMA in kidneys of diabetic mice.
Ameliorative effects of Xue-Fu-Zhu-Yu decoction, Tian-Ma-Gou-Teng-Yin and Wen-Dan decoction on myocardial fibrosis in a hypertensive rat mode.
Dendrobium officinale Kimura et Migo attenuates diabetic cardiomyopathy through inhibiting oxidative stress, inflammation and fibrosis in streptozotocin-induced mice.
Astaxanthin attenuates adriamycin-induced focal segmental glomerulosclerosis.
Anthocyanins inhibit high-glucose-induced cholesterol accumulation and inflammation by activating LXRα pathway in HK-2 cells.
Anti-fibrotic effects of neferine on carbon tetrachloride-induced hepatic fibrosis in mice.
Epithelial-mesenchymal transition in keratocystic odontogenic tumor: possible role in locally aggressive behavior.
Upregulation of miR-142-5p in atherosclerotic plaques and regulation of oxidized low-density lipoprotein-induced apoptosis in macrophages.
Intense Foxp3+ CD25+ regulatory T-cell infiltration is associated with high-grade cutaneous squamous cell carcinoma and counterbalanced by CD8+/Foxp3+ CD25+ ratio.
Mucin1 mediates autocrine transforming growth factor beta signaling through activating the c-Jun N-terminal kinase/activator protein 1 pathway in human hepatocellular carcinoma cells.
Maternal high-fat diet feeding during pregnancy and lactation augments lung inflammation and remodeling in the offspring.
Trps1 is associated with the multidrug resistance of osteosarcoma by regulating MDR1 gene expression.
Gremlin aggravates hyperglycemia-induced podocyte injury by a TGFβ/smad dependent signaling pathway.
Transforming growth factor β induces expression of connective tissue growth factor in hepatic progenitor cells through Smad independent signaling.
High levels of secreted frizzled-related protein 1 correlate with poor prognosis and promote tumourigenesis in gastric cancer.
Attenuating effect of Fufang Xueshuantong Capsule on kidney function in diabetic nephropathy model.
Knockdown of thioredoxin-interacting protein ameliorates high glucose-induced epithelial to mesenchymal transition in renal tubular epithelial cells.
Inhibition of the expression of TGF-β1 and CTGF in human mesangial cells by exendin-4, a glucagon-like peptide-1 receptor agonist.
Wang HH, Huang JH, Sue MH, Ho WC, Hsu YH, Chang KC, Chang MS
EBioMedicine 2021 Feb;64:103213
EBioMedicine 2021 Feb;64:103213
Exercise reduces hyperlipidemia-induced kidney damage in apolipoprotein E-deficient mice.
Qian C, Yang Q, Guo L, Zhu H, You X, Liu H, Sun Y
Experimental and therapeutic medicine 2021 Feb;21(2):153
Experimental and therapeutic medicine 2021 Feb;21(2):153
Myeloid NEMO deficiency promotes tumor immunosuppression partly via MCP1-CCR2 axis.
Yuanyuan L, Yakun L, Zhongyao L, Le Y, Weisong D, Moran G, Hui B, Chunyan L
Experimental cell research 2021 Feb 15;399(2):112467
Experimental cell research 2021 Feb 15;399(2):112467
The Effect of Lecithins Coupled Decorin Nanoliposomes on Treatment of Carbon Tetrachloride-Induced Liver Fibrosis.
Chen G, Zhu Y, Liang X, Wang X, Yu W, Guo J, Zhu L, Ma R
BioMed research international 2020;2020:8815904
BioMed research international 2020;2020:8815904
RUNX3-dependent oxidative epithelial-to-mesenchymal transition in methamphetamine-induced chronic lung injury.
Shi L, Liu BY, Wang X, Zhu MJ, Chen L, Zhou MY, Gu YJ, Cheng L, Wang Y
Cell stress & chaperones 2020 Sep;25(5):793-802
Cell stress & chaperones 2020 Sep;25(5):793-802
Alda-1, an Aldehyde Dehydrogenase 2 Agonist, Improves Cutaneous Wound Healing by Activating Epidermal Keratinocytes via Akt/GSK-3β/β-Catenin Pathway.
Zhang S, Chen C, Ying J, Wei C, Wang L, Yang Z, Qi F
Aesthetic plastic surgery 2020 Jun;44(3):993-1005
Aesthetic plastic surgery 2020 Jun;44(3):993-1005
Preclinical Evaluation of the Novel Small-Molecule MSI-N1014 for Treating Drug-Resistant Colon Cancer via the LGR5/β-catenin/miR-142-3p Network and Reducing Cancer-Associated Fibroblast Transformation.
Yadav VK, Huang YJ, George TA, Wei PL, Sumitra MR, Ho CL, Chang TH, Wu ATH, Huang HS
Cancers 2020 Jun 16;12(6)
Cancers 2020 Jun 16;12(6)
Elk-1 transcriptionally regulates ZC3H4 expression to promote silica-induced epithelial-mesenchymal transition.
Jiang R, Gao Q, Chen M, Yu T
Laboratory investigation; a journal of technical methods and pathology 2020 Jul;100(7):959-973
Laboratory investigation; a journal of technical methods and pathology 2020 Jul;100(7):959-973
FOXO4-DRI alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice.
Zhang C, Xie Y, Chen H, Lv L, Yao J, Zhang M, Xia K, Feng X, Li Y, Liang X, Sun X, Deng C, Liu G
Aging 2020 Jan 20;12(2):1272-1284
Aging 2020 Jan 20;12(2):1272-1284
Inhibitory Effect of Corilagin on miR-21-Regulated Hepatic Fibrosis Signaling Pathway.
Zhou X, Xiong J, Lu S, Luo L, Chen ZL, Yang F, Jin F, Wang Y, Ma Q, Luo YY, Wang YJ, Zhou JB, Liu P, Zhao L
The American journal of Chinese medicine 2019;47(7):1541-1569
The American journal of Chinese medicine 2019;47(7):1541-1569
A small molecule inhibitor MCC950 ameliorates kidney injury in diabetic nephropathy by inhibiting NLRP3 inflammasome activation.
Zhang C, Zhu X, Li L, Ma T, Shi M, Yang Y, Fan Q
Diabetes, metabolic syndrome and obesity : targets and therapy 2019;12:1297-1309
Diabetes, metabolic syndrome and obesity : targets and therapy 2019;12:1297-1309
Aloe-Emodin Ameliorates Renal Fibrosis Via Inhibiting PI3K/Akt/mTOR Signaling Pathway In Vivo and In Vitro.
Dou F, Liu Y, Liu L, Wang J, Sun T, Mu F, Guo Q, Guo C, Jia N, Liu W, Ding Y, Wen A
Rejuvenation research 2019 Jun;22(3):218-229
Rejuvenation research 2019 Jun;22(3):218-229
Progressive Degeneration and Inhibition of Peripheral Nerve Regeneration in the SOD1-G93A Mouse Model of Amyotrophic Lateral Sclerosis.
Deng B, Lv W, Duan W, Liu Y, Li Z, Ma Y, Zhang G, Song X, Cui C, Qi X, Li Y, Li C
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(6):2358-2372
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(6):2358-2372
Thioredoxin-interacting protein deficiency ameliorates kidney inflammation and fibrosis in mice with unilateral ureteral obstruction.
Wu M, Li R, Hou Y, Song S, Han W, Chen N, Du Y, Ren Y, Shi Y
Laboratory investigation; a journal of technical methods and pathology 2018 Sep;98(9):1211-1224
Laboratory investigation; a journal of technical methods and pathology 2018 Sep;98(9):1211-1224
miR-663a inhibits tumor growth and invasion by regulating TGF-β1 in hepatocellular carcinoma.
Zhang C, Chen B, Jiao A, Li F, Sun N, Zhang G, Zhang J
BMC cancer 2018 Nov 28;18(1):1179
BMC cancer 2018 Nov 28;18(1):1179
CD103+CD8+ T lymphocytes in non-small cell lung cancer are phenotypically and functionally primed to respond to PD-1 blockade.
Wang P, Huang B, Gao Y, Yang J, Liang Z, Zhang N, Fu X, Li L
Cellular immunology 2018 Mar;325:48-55
Cellular immunology 2018 Mar;325:48-55
Slit2-Robo2 signaling modulates the fibrogenic activity and migration of hepatic stellate cells.
Zeng Z, Wu Y, Cao Y, Yuan Z, Zhang Y, Zhang DY, Hasegawa D, Friedman SL, Guo J
Life sciences 2018 Jun 15;203:39-47
Life sciences 2018 Jun 15;203:39-47
Modulation of TGF‑β activity by latent TGF‑β‑binding protein 1 in human osteoarthritis fibroblast‑like synoviocytes.
Wang X, Dong C, Li N, Ma Q, Yun Z, Cai C, An M, Ma B
Molecular medicine reports 2018 Jan;17(1):1893-1900
Molecular medicine reports 2018 Jan;17(1):1893-1900
Effects of Ovariectomy in an hSOD1-G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis (ALS).
Yan L, Liu Y, Sun C, Zheng Q, Hao P, Zhai J, Liu Y
Medical science monitor : international medical journal of experimental and clinical research 2018 Feb 2;24:678-686
Medical science monitor : international medical journal of experimental and clinical research 2018 Feb 2;24:678-686
Proefferocytic Therapy Promotes Transforming Growth Factor-β Signaling and Prevents Aneurysm Formation.
Kojima Y, Werner N, Ye J, Nanda V, Tsao N, Wang Y, Flores AM, Miller CL, Weissman I, Deng H, Xu B, Dalman RL, Eken SM, Pelisek J, Li Y, Maegdefessel L, Leeper NJ
Circulation 2018 Feb 13;137(7):750-753
Circulation 2018 Feb 13;137(7):750-753
AGR2 promotes the proliferation, migration and regulates epithelial-mesenchymal transition in salivary adenoid cystic carcinoma.
Ma SR, Mao L, Deng WW, Li YC, Bu LL, Yu GT, Zhang WF, Sun ZJ
American journal of translational research 2017;9(2):507-519
American journal of translational research 2017;9(2):507-519
Deletion of diacylglycerol-responsive TRPC genes attenuates diabetic nephropathy by inhibiting activation of the TGFβ1 signaling pathway.
Liu B, He X, Li S, Xu B, Birnbaumer L, Liao Y
American journal of translational research 2017;9(12):5619-5630
American journal of translational research 2017;9(12):5619-5630
Treadmill Exercise Exerts Neuroprotection and Regulates Microglial Polarization and Oxidative Stress in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer's Disease.
Lu Y, Dong Y, Tucker D, Wang R, Ahmed ME, Brann D, Zhang Q
Journal of Alzheimer's disease : JAD 2017;56(4):1469-1484
Journal of Alzheimer's disease : JAD 2017;56(4):1469-1484
Sphingosine kinase 1 protects renal tubular epithelial cells from renal fibrosis via induction of autophagy.
Du C, Ren Y, Yao F, Duan J, Zhao H, Du Y, Xiao X, Duan H, Shi Y
The international journal of biochemistry & cell biology 2017 Sep;90:17-28
The international journal of biochemistry & cell biology 2017 Sep;90:17-28
Inhibition of airway remodeling and inflammation by isoforskolin in PDGF-induced rat ASMCs and OVA-induced rat asthma model.
Liang X, Wang J, Chen W, Ma X, Wang Y, Nagao N, Weng W, Huang J, Liu J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:275-286
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:275-286
Luteolin-7-diglucuronide attenuates isoproterenol-induced myocardial injury and fibrosis in mice.
Ning BB, Zhang Y, Wu DD, Cui JG, Liu L, Wang PW, Wang WJ, Zhu WL, Chen Y, Zhang T
Acta pharmacologica Sinica 2017 Mar;38(3):331-341
Acta pharmacologica Sinica 2017 Mar;38(3):331-341
Effects of exogenous thymosin β4 on carbon tetrachloride-induced liver injury and fibrosis.
Li X, Wang L, Chen C
Scientific reports 2017 Jul 19;7(1):5872
Scientific reports 2017 Jul 19;7(1):5872
Expression of fibrosis-related molecules in the oral mucosa of six animal species: A reference for selecting animal models.
Sa G, Xiong X, Ren J, Zhao Y, He S
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2017 Jan 1;96:472-478
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2017 Jan 1;96:472-478
Oncogenic Kras drives invasion and maintains metastases in colorectal cancer.
Boutin AT, Liao WT, Wang M, Hwang SS, Karpinets TV, Cheung H, Chu GC, Jiang S, Hu J, Chang K, Vilar E, Song X, Zhang J, Kopetz S, Futreal A, Wang YA, Kwong LN, DePinho RA
Genes & development 2017 Feb 15;31(4):370-382
Genes & development 2017 Feb 15;31(4):370-382
Effects of polysaccharide from Physalis alkekengi var. francheti on liver injury and intestinal microflora in type-2 diabetic mice.
Zhao X, Chen Z, Yin Y, Li X
Pharmaceutical biology 2017 Dec;55(1):2020-2025
Pharmaceutical biology 2017 Dec;55(1):2020-2025
Neuronal zinc-α2-glycoprotein is decreased in temporal lobe epilepsy in patients and rats.
Liu Y, Wang T, Liu X, Wei X, Xu T, Yin M, Ding X, Mo L, Chen L
Neuroscience 2017 Aug 15;357:56-66
Neuroscience 2017 Aug 15;357:56-66
Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway.
Liu J, Wu J, Sun A, Sun Y, Yu X, Liu N, Dong S, Yang F, Zhang L, Zhong X, Xu C, Lu F, Zhang W
Cell & bioscience 2016;6:33
Cell & bioscience 2016;6:33
Pancreatic Kininogenase Ameliorates Renal Fibrosis in Streptozotocin Induced-Diabetic Nephropathy Rat.
Zhu D, Zhang L, Cheng L, Ren L, Tang J, Sun D
Kidney & blood pressure research 2016;41(1):9-17
Kidney & blood pressure research 2016;41(1):9-17
Mixed Aqueous Extract of Salvia Miltiorrhiza Reduces Blood Pressure through Inhibition of Vascular Remodelling and Oxidative Stress in Spontaneously Hypertensive Rats.
Zhang J, An SJ, Fu JQ, Liu P, Shao TM, Li M, Li X, Jiao Z, Chai XQ
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(1-2):347-360
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(1-2):347-360
Naringenin Ameliorated Kidney Injury through Let-7a/TGFBR1 Signaling in Diabetic Nephropathy.
Yan N, Wen L, Peng R, Li H, Liu H, Peng H, Sun Y, Wu T, Chen L, Duan Q, Sun Y, Zhou Q, Wei L, Zhang Z
Journal of diabetes research 2016;2016:8738760
Journal of diabetes research 2016;2016:8738760
Overexpression of Prolyl-4-Hydroxylase-α1 Stabilizes but Increases Shear Stress-Induced Atherosclerotic Plaque in Apolipoprotein E-Deficient Mice.
Cao XQ, Liu XX, Li MM, Zhang Y, Chen L, Wang L, Di MX, Zhang M
Disease markers 2016;2016:1701637
Disease markers 2016;2016:1701637
Co-expression of LASS2 and TGF-β1 predicts poor prognosis in hepatocellular carcinoma.
Ruan H, Wang T, Yang C, Jin G, Gu D, Deng X, Wang C, Qin W, Jin H
Scientific reports 2016 Sep 1;6:32421
Scientific reports 2016 Sep 1;6:32421
Usp2-69 overexpression slows down the progression of rat anti-Thy1.1 nephritis.
Mao X, Luo W, Sun J, Yang N, Zhang LW, Zhao Z, Zhang Z, Wu H
Experimental and molecular pathology 2016 Oct;101(2):249-258
Experimental and molecular pathology 2016 Oct;101(2):249-258
Regulation of a TGF-β1-CD147 self-sustaining network in the differentiation plasticity of hepatocellular carcinoma cells.
Wu J, Lu M, Li Y, Shang YK, Wang SJ, Meng Y, Wang Z, Li ZS, Chen H, Chen ZN, Bian H
Oncogene 2016 Oct 20;35(42):5468-5479
Oncogene 2016 Oct 20;35(42):5468-5479
scAAV9-VEGF prolongs the survival of transgenic ALS mice by promoting activation of M2 microglia and the PI3K/Akt pathway.
Wang Y, Duan W, Wang W, Di Wen, Liu Y, Liu Y, Li Z, Hu H, Lin H, Cui C, Li D, Dong H, Li C
Brain research 2016 Oct 1;1648(Pt A):1-10
Brain research 2016 Oct 1;1648(Pt A):1-10
Tanshinone IIA attenuates epithelial-mesenchymal transition to inhibit the tracheal narrowing.
Duan H, Ma L, Liu H, Zhang Y, Zhang Z, Yan X, Li X
The Journal of surgical research 2016 Nov;206(1):252-262
The Journal of surgical research 2016 Nov;206(1):252-262
Impaired T cell function in malignant pleural effusion is caused by TGF-β derived predominantly from macrophages.
Li L, Yang L, Wang L, Wang F, Zhang Z, Li J, Yue D, Chen X, Ping Y, Huang L, Zhang B, Zhang Y
International journal of cancer 2016 Nov 15;139(10):2261-9
International journal of cancer 2016 Nov 15;139(10):2261-9
Mitochondria-targeted peptide SS-31 attenuates renal injury via an antioxidant effect in diabetic nephropathy.
Hou Y, Li S, Wu M, Wei J, Ren Y, Du C, Wu H, Han C, Duan H, Shi Y
American journal of physiology. Renal physiology 2016 Mar 15;310(6):F547-59
American journal of physiology. Renal physiology 2016 Mar 15;310(6):F547-59
Deletion of interleukin-6 alleviated interstitial fibrosis in streptozotocin-induced diabetic cardiomyopathy of mice through affecting TGFβ1 and miR-29 pathways.
Zhang Y, Wang JH, Zhang YY, Wang YZ, Wang J, Zhao Y, Jin XX, Xue GL, Li PH, Sun YL, Huang QH, Song XT, Zhang ZR, Gao X, Yang BF, Du ZM, Pan ZW
Scientific reports 2016 Mar 14;6:23010
Scientific reports 2016 Mar 14;6:23010
Carboxy-terminal modulator protein attenuated extracellular matrix deposit by inhibiting phospho-Akt, TGF-β1 and α-SMA in kidneys of diabetic mice.
Chen N, Hao J, Li L, Li F, Liu S, Duan H
Biochemical and biophysical research communications 2016 Jun 10;474(4):753-760
Biochemical and biophysical research communications 2016 Jun 10;474(4):753-760
Ameliorative effects of Xue-Fu-Zhu-Yu decoction, Tian-Ma-Gou-Teng-Yin and Wen-Dan decoction on myocardial fibrosis in a hypertensive rat mode.
Zhang G, Yang G, Deng Y, Zhao X, Yang Y, Rao J, Wang W, Liu X, He J, Lv L
BMC complementary and alternative medicine 2016 Feb 6;16:56
BMC complementary and alternative medicine 2016 Feb 6;16:56
Dendrobium officinale Kimura et Migo attenuates diabetic cardiomyopathy through inhibiting oxidative stress, inflammation and fibrosis in streptozotocin-induced mice.
Zhang Z, Zhang D, Dou M, Li Z, Zhang J, Zhao X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:1350-1358
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:1350-1358
Astaxanthin attenuates adriamycin-induced focal segmental glomerulosclerosis.
Liu G, Shi Y, Peng X, Liu H, Peng Y, He L
Pharmacology 2015;95(3-4):193-200
Pharmacology 2015;95(3-4):193-200
Anthocyanins inhibit high-glucose-induced cholesterol accumulation and inflammation by activating LXRα pathway in HK-2 cells.
Du C, Shi Y, Ren Y, Wu H, Yao F, Wei J, Wu M, Hou Y, Duan H
Drug design, development and therapy 2015;9:5099-113
Drug design, development and therapy 2015;9:5099-113
Anti-fibrotic effects of neferine on carbon tetrachloride-induced hepatic fibrosis in mice.
Chen MS, Zhang JH, Wang JL, Gao L, Chen XX, Xiao JH
The American journal of Chinese medicine 2015;43(2):231-40
The American journal of Chinese medicine 2015;43(2):231-40
Epithelial-mesenchymal transition in keratocystic odontogenic tumor: possible role in locally aggressive behavior.
Zhong WQ, Chen G, Zhang W, Ren JG, Wu ZX, Zhao Y, Liu B, Zhao YF
BioMed research international 2015;2015:168089
BioMed research international 2015;2015:168089
Upregulation of miR-142-5p in atherosclerotic plaques and regulation of oxidized low-density lipoprotein-induced apoptosis in macrophages.
Xu R, Bi C, Song J, Wang L, Ge C, Liu X, Zhang M
Molecular medicine reports 2015 May;11(5):3229-34
Molecular medicine reports 2015 May;11(5):3229-34
Intense Foxp3+ CD25+ regulatory T-cell infiltration is associated with high-grade cutaneous squamous cell carcinoma and counterbalanced by CD8+/Foxp3+ CD25+ ratio.
Azzimonti B, Zavattaro E, Provasi M, Vidali M, Conca A, Catalano E, Rimondini L, Colombo E, Valente G
The British journal of dermatology 2015 Jan;172(1):64-73
The British journal of dermatology 2015 Jan;172(1):64-73
Mucin1 mediates autocrine transforming growth factor beta signaling through activating the c-Jun N-terminal kinase/activator protein 1 pathway in human hepatocellular carcinoma cells.
Li Q, Liu G, Shao D, Wang J, Yuan H, Chen T, Zhai R, Ni W, Tai G
The international journal of biochemistry & cell biology 2015 Feb;59:116-25
The international journal of biochemistry & cell biology 2015 Feb;59:116-25
Maternal high-fat diet feeding during pregnancy and lactation augments lung inflammation and remodeling in the offspring.
Song Y, Yu Y, Wang D, Chai S, Liu D, Xiao X, Huang Y
Respiratory physiology & neurobiology 2015 Feb 1;207:1-6
Respiratory physiology & neurobiology 2015 Feb 1;207:1-6
Trps1 is associated with the multidrug resistance of osteosarcoma by regulating MDR1 gene expression.
Jia M, Hu J, Li W, Su P, Zhang H, Zhang X, Zhou G
FEBS letters 2014 Mar 3;588(5):801-10
FEBS letters 2014 Mar 3;588(5):801-10
Gremlin aggravates hyperglycemia-induced podocyte injury by a TGFβ/smad dependent signaling pathway.
Li G, Li Y, Liu S, Shi Y, Chi Y, Liu G, Shan T
Journal of cellular biochemistry 2013 Sep;114(9):2101-13
Journal of cellular biochemistry 2013 Sep;114(9):2101-13
Transforming growth factor β induces expression of connective tissue growth factor in hepatic progenitor cells through Smad independent signaling.
Ding ZY, Jin GN, Liang HF, Wang W, Chen WX, Datta PK, Zhang MZ, Zhang B, Chen XP
Cellular signalling 2013 Oct;25(10):1981-92
Cellular signalling 2013 Oct;25(10):1981-92
High levels of secreted frizzled-related protein 1 correlate with poor prognosis and promote tumourigenesis in gastric cancer.
Qu Y, Ray PS, Li J, Cai Q, Bagaria SP, Moran C, Sim MS, Zhang J, Turner RR, Zhu Z, Cui X, Liu B
European journal of cancer (Oxford, England : 1990) 2013 Nov;49(17):3718-28
European journal of cancer (Oxford, England : 1990) 2013 Nov;49(17):3718-28
Attenuating effect of Fufang Xueshuantong Capsule on kidney function in diabetic nephropathy model.
Zhang Q, Xiao X, Li M, Li W, Yu M, Zhang H, Sun X, Mao L, Xiang H
Journal of natural medicines 2013 Jan;67(1):86-97
Journal of natural medicines 2013 Jan;67(1):86-97
Knockdown of thioredoxin-interacting protein ameliorates high glucose-induced epithelial to mesenchymal transition in renal tubular epithelial cells.
Wei J, Shi Y, Hou Y, Ren Y, Du C, Zhang L, Li Y, Duan H
Cellular signalling 2013 Dec;25(12):2788-96
Cellular signalling 2013 Dec;25(12):2788-96
Inhibition of the expression of TGF-β1 and CTGF in human mesangial cells by exendin-4, a glucagon-like peptide-1 receptor agonist.
Li W, Cui M, Wei Y, Kong X, Tang L, Xu D
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2012;30(3):749-57
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2012;30(3):749-57
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TGF- beta 1 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human TGF- beta 1. This antibody recognizes human,mouse,rat antigen. The TGF- beta 1 antibody has been validated for the following applications: ELISA, IHC analysis.