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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
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- Product number
- MAB2047 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB2047, RRID:AB_1672303
- Product name
- CTSL1 monoclonal antibody, clone 2H7
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against partial recombinant CTSL1.
- Isotype
- IgG
- Antibody clone number
- 2H7
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: a putative mechanism.
The lysosomal cysteine protease cathepsin L regulates keratinocyte proliferation by control of growth factor recycling.
Processing and activation of lysosomal proteinases.
Zheng X, Chu F, Chou PM, Gallati C, Dier U, Mirkin BL, Mousa SA, Rebbaa A
American journal of physiology. Cell physiology 2009 Jan;296(1):C65-74
American journal of physiology. Cell physiology 2009 Jan;296(1):C65-74
The lysosomal cysteine protease cathepsin L regulates keratinocyte proliferation by control of growth factor recycling.
Reinheckel T, Hagemann S, Dollwet-Mack S, Martinez E, Lohmüller T, Zlatkovic G, Tobin DJ, Maas-Szabowski N, Peters C
Journal of cell science 2005 Aug 1;118(Pt 15):3387-95
Journal of cell science 2005 Aug 1;118(Pt 15):3387-95
Processing and activation of lysosomal proteinases.
Ishidoh K, Kominami E
Biological chemistry 2002 Dec;383(12):1827-31
Biological chemistry 2002 Dec;383(12):1827-31
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Supportive validation
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- Abnova Corporation (provider)
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- Experimental details
- The recombinant fusion proteins and cell lysate were resolved by SDS-PAGE and probed with CTSL1 monoclonal antibody, clone 2H7 (Cat # MAB2047) (1:1000).Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.Lane 1 : CTSB.Lane 2 : CTSD.Lane 3 : CTSK.Lane 4 : CTSL1.Lane 5 : CTSS.Lane 6 : A-549.
