Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- NB100-1775 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-1775, RRID:AB_10124480
- Product name
- Mouse Monoclonal Cathepsin L Antibody
- Antibody type
- Monoclonal
- Description
- Unpurified. Reacts specifically with native and denatured forms of human cathepsin L and procathepsin L.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Antigen sequence
Recognizes an epitope within amino
acid residues GYGFEST (265-271 in p
rocathepsin L and 169-175 in the ma
ture cathepsin L molecule).- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Restoration of CTSD (cathepsin D) and lysosomal function in stroke is neuroprotective.
The ubiquitin ligase Mindbomb 1 coordinates gastrointestinal secretory cell maturation.
Transient expression of progesterone receptor and cathepsin-l in human granulosa cells during the periovulatory period.
Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: a putative mechanism.
Senescence-initiated reversal of drug resistance: specific role of cathepsin L.
Senescence-initiated reversal of drug resistance: specific role of cathepsin L.
Monoclonal antibodies against cathepsin L and procathepsin L of different species.
Hossain MI, Marcus JM, Lee JH, Garcia PL, Singh V, Shacka JJ, Zhang J, Gropen TI, Falany CN, Andrabi SA
Autophagy 2021 Jun;17(6):1330-1348
Autophagy 2021 Jun;17(6):1330-1348
The ubiquitin ligase Mindbomb 1 coordinates gastrointestinal secretory cell maturation.
Capoccia BJ, Jin RU, Kong YY, Peek RM Jr, Fassan M, Rugge M, Mills JC
The Journal of clinical investigation 2013 Apr;123(4):1475-91
The Journal of clinical investigation 2013 Apr;123(4):1475-91
Transient expression of progesterone receptor and cathepsin-l in human granulosa cells during the periovulatory period.
García V, Kohen P, Maldonado C, Sierralta W, Muñoz A, Villarroel C, Strauss JF 3rd, Devoto L
Fertility and sterility 2012 Mar;97(3):707-13.e1
Fertility and sterility 2012 Mar;97(3):707-13.e1
Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: a putative mechanism.
Zheng X, Chu F, Chou PM, Gallati C, Dier U, Mirkin BL, Mousa SA, Rebbaa A
American journal of physiology. Cell physiology 2009 Jan;296(1):C65-74
American journal of physiology. Cell physiology 2009 Jan;296(1):C65-74
Senescence-initiated reversal of drug resistance: specific role of cathepsin L.
Zheng X, Chou PM, Mirkin BL, Rebbaa A
Cancer research 2004 Mar 1;64(5):1773-80
Cancer research 2004 Mar 1;64(5):1773-80
Senescence-initiated reversal of drug resistance: specific role of cathepsin L.
Zheng X, Chou PM, Mirkin BL, Rebbaa A
Cancer research 2004 Mar 1;64(5):1773-80
Cancer research 2004 Mar 1;64(5):1773-80
Monoclonal antibodies against cathepsin L and procathepsin L of different species.
Weber E, Bahn H, Günther D
Hybridoma 1997 Apr;16(2):159-66
Hybridoma 1997 Apr;16(2):159-66
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Cathepsin L Antibody (33/2) [NB100-1775] - Whole cell extract of Mv 1 Lu cultured mink lung was separated on SDS-PAGE and blotted with Monoclonal Anti-Cathepsin L. The antibody was developed with Goat Anti-Mouse IgG (Fab), AlkPhos Conjugate and NBT/BCIP substrate. Lane A: Antibody dilution 1:400. Lane B: Negative control (only secondary antibody).