Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 12672-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12672-1-AP, RRID:AB_10639526
- Product name
- SHCBP1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SHCBP1 antibody (Cat. #12672-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references SHCBP1 interacting with EOGT enhances O-GlcNAcylation of NOTCH1 and promotes the development of pancreatic cancer.
SHCBP1 regulates STAT3/c-Myc signaling activation to promote tumor progression in penile cancer.
FGF13 interaction with SHCBP1 activates AKT-GSK3α/β signaling and promotes the proliferation of A549 cells.
Oroxylin A inhibits carcinogen-induced skin tumorigenesis through inhibition of inflammation by regulating SHCBP1 in mice.
SHCBP1 promotes synovial sarcoma cell metastasis via targeting TGF-β1/Smad signaling pathway and is associated with poor prognosis.
Measles virus nonstructural C protein modulates viral RNA polymerase activity by interacting with host protein SHCBP1.
Yang C, Hu JF, Zhan Q, Wang ZW, Li G, Pan JJ, Huang L, Liao CY, Huang Y, Tian YF, Shen BY, Chen JZ, Wang YD, Chen S
Genomics 2021 Mar;113(2):827-842
Genomics 2021 Mar;113(2):827-842
SHCBP1 regulates STAT3/c-Myc signaling activation to promote tumor progression in penile cancer.
Mo M, Tong S, Yin H, Jin Z, Zu X, Hu X
American journal of cancer research 2020;10(10):3138-3156
American journal of cancer research 2020;10(10):3138-3156
FGF13 interaction with SHCBP1 activates AKT-GSK3α/β signaling and promotes the proliferation of A549 cells.
Lu H, Yin M, Wang L, Cheng J, Cheng W, An H, Zhang T
Cancer biology & therapy 2020 Nov 1;21(11):1014-1024
Cancer biology & therapy 2020 Nov 1;21(11):1014-1024
Oroxylin A inhibits carcinogen-induced skin tumorigenesis through inhibition of inflammation by regulating SHCBP1 in mice.
Huang H, Cai H, Zhang L, Hua Z, Shi J, Wei Y
International immunopharmacology 2020 Mar;80:106123
International immunopharmacology 2020 Mar;80:106123
SHCBP1 promotes synovial sarcoma cell metastasis via targeting TGF-β1/Smad signaling pathway and is associated with poor prognosis.
Peng C, Zhao H, Song Y, Chen W, Wang X, Liu X, Zhang C, Zhao J, Li J, Cheng G, Wu D, Gao C, Wang X
Journal of experimental & clinical cancer research : CR 2017 Oct 11;36(1):141
Journal of experimental & clinical cancer research : CR 2017 Oct 11;36(1):141
Measles virus nonstructural C protein modulates viral RNA polymerase activity by interacting with host protein SHCBP1.
Ito M, Iwasaki M, Takeda M, Nakamura T, Yanagi Y, Ohno S
Journal of virology 2013 Sep;87(17):9633-42
Journal of virology 2013 Sep;87(17):9633-42
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 12672-1-AP(SHCBP1 antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human tonsillitis using 12672-1-AP(SHCBP1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SHCBP1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SHCBP1. This antibody recognizes human, mouse antigen. The SHCBP1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.