FNab00262

antibody from FineTest Biotech
Targeting: AKR1C3 DDX, HAKRB, HSD17B5, KIAA0119, PGFS
Provider product page for FNab00262
Western blot
ELISA
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
FNab00262 - Provider product page
Provider
FineTest Biotech
Product name
AKR1C3 antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha, 11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene.
Reactivity
Human, Rat
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
aldo-keto reductase family 1, membe
r C3 (3-alpha hydroxysteroid dehydr
ogenase, type II)
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)
AKR1C3 protein structure - FNab00262 shown in red.