Antibody data
- Antibody Data
- Antigen structure
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- Product number
- BS8146 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- ALKBH2 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human ALKBH2.
- Description
- ALKBH2 (alkB, alkylation repair homolog 2), also known as ABH2, is a 261 amino acid protein that localizes to the nucleus and belongs to the alkB family. Expressed in heart, colon, liver, testis, ovary, prostate and small intestine, ALKBH2 uses iron as a cofactor and functions as a dioxygenase that catalyzes the repair of alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine. ALKBH2 is functionally activated by ascorbate and requires oxygen and Ï«-ketoglutarate for enzymatic activity. The gene encoding ALKBH2 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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