BS8146

antibody from Bioworld Technology, Inc
Targeting: ALKBH2 ABH2, MGC90512
Provider product page for BS8146
Western blot
Immunohistochemistry

Antibody data

Product number
BS8146 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ALKBH2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human ALKBH2.
Description
ALKBH2 (alkB, alkylation repair homolog 2), also known as ABH2, is a 261 amino acid protein that localizes to the nucleus and belongs to the alkB family. Expressed in heart, colon, liver, testis, ovary, prostate and small intestine, ALKBH2 uses iron as a cofactor and functions as a dioxygenase that catalyzes the repair of alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine. ALKBH2 is functionally activated by ascorbate and requires oxygen and Ï«-ketoglutarate for enzymatic activity. The gene encoding ALKBH2 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ALKBH2 protein structure - BS8146 shown in red.