BS7677

antibody from Bioworld Technology, Inc
Targeting: UGT2B7 UGT2B9
Provider product page for BS7677
Western blot
Immunohistochemistry

Antibody data

Product number
BS7677 - Provider product page
Provider
Bioworld Technology, Inc
Product name
UGT2B7 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human UGT2B7.
Description
UDP-glucuronosyltransferase isoenzymes (UGTs) catalyze the glucuronidation of small lipophilic molecules, thereby regulating the bioactivity and metabolic fate of a wide range of endogenous compounds and xenobiotics. Glucuronidation increases the polarity of lipophilic molecules and facilitates their entry into aqueous compartments and, ultimately, their excretion. In essence, glucuronidation provides a protective function by terminating or attenuating the biological activity of its substrates. The UGT2B family of isoenzymes are highly expressed in liver, but are also detected in several non-hepatic tissues, including skin, breast, prostate, intestine, placenta and lung. UGT2B7 (UDP-glucuronosyltransferase 2B7), also known as UGTB2B9, is a 529 amino acid singlepass membrane protein that localizes to both the microsome and the endoplasmic reticulum and belongs to the UDP-glycosyltransferase family. Exhibiting a unique specificity for 3,4-catechol estrogens and estriol, UGT2B7 is thought to play an important role in the regulation of both the level and the activity of estrogen metabolites.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
UGT2B7 protein structure - BS7677 shown in red.