Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 12439-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12439-1-AP, RRID:AB_2302517
- Product name
- CREST antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CREST antibody (Cat. #12439-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Global Chromatin Changes Resulting from Single-Gene Inactivation-The Role of SMARCB1 in Malignant Rhabdoid Tumor.
Protein expression pattern of calcium-responsive transactivator in early postnatal and adult testes.
Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies.
CREST in the Nucleus Accumbens Core Regulates Cocaine Conditioned Place Preference, Cocaine-Seeking Behavior, and Synaptic Plasticity.
Dysregulation of chromatin remodelling complexes in amyotrophic lateral sclerosis.
Mutation of neuron-specific chromatin remodeling subunit BAF53b: rescue of plasticity and memory by manipulating actin remodeling.
Calcium-responsive transactivator (CREST) protein shares a set of structural and functional traits with other proteins associated with amyotrophic lateral sclerosis.
Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways.
Exome sequencing to identify de novo mutations in sporadic ALS trios.
Kenny C, O'Meara E, Ulaş M, Hokamp K, O'Sullivan MJ
Cancers 2021 May 23;13(11)
Cancers 2021 May 23;13(11)
Protein expression pattern of calcium-responsive transactivator in early postnatal and adult testes.
Du A, Li L, Jiao Z, Zhu G, Peng T, Li H
Histochemistry and cell biology 2021 Apr;155(4):491-502
Histochemistry and cell biology 2021 Apr;155(4):491-502
Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies.
Park S, Park SK, Watanabe N, Hashimoto T, Iwatsubo T, Shelkovnikova TA, Liebman SW
PLoS genetics 2019 Aug;15(8):e1008308
PLoS genetics 2019 Aug;15(8):e1008308
CREST in the Nucleus Accumbens Core Regulates Cocaine Conditioned Place Preference, Cocaine-Seeking Behavior, and Synaptic Plasticity.
Alaghband Y, Kramár E, Kwapis JL, Kim ES, Hemstedt TJ, López AJ, White AO, Al-Kachak A, Aimiuwu OV, Bodinayake KK, Oparaugo NC, Han J, Lattal KM, Wood MA
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Oct 31;38(44):9514-9526
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Oct 31;38(44):9514-9526
Dysregulation of chromatin remodelling complexes in amyotrophic lateral sclerosis.
Tibshirani M, Zhao B, Gentil BJ, Minotti S, Marques C, Keith J, Rogaeva E, Zinman L, Rouaux C, Robertson J, Durham HD
Human molecular genetics 2017 Nov 1;26(21):4142-4152
Human molecular genetics 2017 Nov 1;26(21):4142-4152
Mutation of neuron-specific chromatin remodeling subunit BAF53b: rescue of plasticity and memory by manipulating actin remodeling.
Vogel Ciernia A, Kramár EA, Matheos DP, Havekes R, Hemstedt TJ, Magnan CN, Sakata K, Tran A, Azzawi S, Lopez A, Dang R, Wang W, Trieu B, Tong J, Barrett RM, Post RJ, Baldi P, Abel T, Lynch G, Wood MA
Learning & memory (Cold Spring Harbor, N.Y.) 2017 May;24(5):199-209
Learning & memory (Cold Spring Harbor, N.Y.) 2017 May;24(5):199-209
Calcium-responsive transactivator (CREST) protein shares a set of structural and functional traits with other proteins associated with amyotrophic lateral sclerosis.
Kukharsky MS, Quintiero A, Matsumoto T, Matsukawa K, An H, Hashimoto T, Iwatsubo T, Buchman VL, Shelkovnikova TA
Molecular neurodegeneration 2015 Apr 10;10:20
Molecular neurodegeneration 2015 Apr 10;10:20
Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways.
Staahl BT, Tang J, Wu W, Sun A, Gitler AD, Yoo AS, Crabtree GR
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Jun 19;33(25):10348-61
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Jun 19;33(25):10348-61
Exome sequencing to identify de novo mutations in sporadic ALS trios.
Chesi A, Staahl BT, Jovičić A, Couthouis J, Fasolino M, Raphael AR, Yamazaki T, Elias L, Polak M, Kelly C, Williams KL, Fifita JA, Maragakis NJ, Nicholson GA, King OD, Reed R, Crabtree GR, Blair IP, Glass JD, Gitler AD
Nature neuroscience 2013 Jul;16(7):851-5
Nature neuroscience 2013 Jul;16(7):851-5
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- COLO 320 cells were subjected to SDS PAGE followed by western blot with 12439-1-AP(CREST antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using SS18L1 antibody 12439-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-CREST (IP:12439-1-AP, 3ug; Detection:12439-1-AP 1:1000) with mouse brain tissue lysate 6000ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 12439-1-AP(CREST antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue