11-8005-25

antibody from ABEOMICS Inc.
Targeting: PACS1 FLJ10209, KIAA1175
Provider product page for 11-8005-25

Antibody data

Product number
11-8005-25 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-PACS-1 Antibody
Antibody type
Polyclonal
Description
PACS1 or phosphofurin acidic cluster sorting protein 1 belongs to the PACS familyof proteins and is involved in protein trafficking. PACS1 contains an acidic cluster sorting motifs and plays an important role in the localization of trans-Golgi network (TGN) membrane proteins. It has also been implicated in secretory granule biogenesis. In order to enable HIV-1 to escape immune surveillance, PACS-1 is also reported to be involved in HIV-1 Nef-mediated removal of MHC-I from the cell surface to the trans-golgi network. Diseases caused by mutation in this gene include mental retardation (MRD17) and AIDS. PACS1 has expression in adipose tissue, liver, spleen, bone, blood, brain. It has 2 isoforms produced by alternative splicing.
Reactivity
Human
Host
Rabbit
Antigen sequence
A partial length recombinant PACS-1
protein (amino acids 150-400) was
used as the immunogen for this anti
body.
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
PACS1 protein structure - 11-8005-25 shown in red.