Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 11-12019 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-SPZ1/TSP1 Antibody
- Antibody type
- Polyclonal
- Description
- Spz1, a bHLH-zip protein, acts as a proto-oncogene regulated by a MAPK signaling pathway that can increase cell proliferation and tumorigenic activity as well as leading to primary tumor formation (15899793). It is expressed specifically in the testis and epididymis (11165476). Spz1 is a specific binding partner of the gamma2 catalytic subunit of Phosphatase-1c-gamma (PP1c-gamma). The interaction between Spz1 and PP1cgamma2 may be required for proper regulation of spermatogenesis and fertility in males.
- Reactivity
- Human
- Host
- Rabbit
- Antigen sequence
A partial length recombinant SPZ1/T
SP1 protein (amino acids 10-213) wa
s used as the immunogen for this an
tibody.- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
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Supportive validation
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- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Expression analysis of SPZ1/TSP1. Anti-SPZ1/TSP1 antibody (11-12019) was used at 1 µg/ml on h Skeletal muscle lysate.