Antibody data
- Antibody Data
- Antigen structure
- References [96]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 17479-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17479-1-AP, RRID:AB_2217473
- Product name
- YTHDF1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated YTHDF1 antibody (Cat. #17479-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references YTHDF1 Aggravates the Progression of Cervical Cancer Through m6A-Mediated Up-Regulation of RANBP2.
YTHDF1 and YTHDF2 are associated with better patient survival and an inflamed tumor-immune microenvironment in non-small-cell lung cancer.
Insufficient Radiofrequency Ablation Promotes Hepatocellular Carcinoma Metastasis Through N6-Methyladenosine mRNA Methylation-Dependent Mechanism.
Vitamin B12 Deficiency Dysregulates m6A mRNA Methylation of Genes Involved in Neurological Functions.
Differential roles of YTHDF1 and YTHDF3 in embryonic stem cell-derived cardiomyocyte differentiation.
METTL3-dependent RNA m6A dysregulation contributes to neurodegeneration in Alzheimer's disease through aberrant cell cycle events.
METTL3-m6A-Rubicon axis inhibits autophagy in nonalcoholic fatty liver disease.
METTL3 regulates hippocampal gene transcription via N6-methyladenosine methylation in sevoflurane-induced postoperative cognitive dysfunction mouse.
Streptozotocin-Induced Astrocyte Mitochondrial Dysfunction Is Ameliorated by FTO Inhibitor MO-I-500.
The m6 A Readers YTHDF1 and YTHDF2 Synergistically Control Cerebellar Parallel Fiber Growth by Regulating Local Translation of the Key Wnt5a Signaling Components in Axons.
The pathological tissue expression pattern and clinical significance of m6A-regulatory genes in non-small cell lung cancer.
Mettl3 promotes oxLDL-mediated inflammation through activating STAT1 signaling.
Stabilization of UCA1 by N6-methyladenosine RNA methylation modification promotes colorectal cancer progression.
The m6A "reader" YTHDF1 promotes osteogenesis of bone marrow mesenchymal stem cells through translational control of ZNF839.
WNT/β-catenin-suppressed FTO expression increases m6A of c-Myc mRNA to promote tumor cell glycolysis and tumorigenesis.
Curcumin prevents obesity by targeting TRAF4-induced ubiquitylation in m6 A-dependent manner.
YTHDF1 Promotes Gastric Carcinogenesis by Controlling Translation of FZD7.
m6A RNA methylation regulates the fate of endogenous retroviruses.
Comparison of RNA m6A and DNA methylation profiles between mouse female germline stem cells and STO cells.
MYC promotes cancer progression by modulating m6 A modifications to suppress target gene translation.
Post-transcriptional regulation of antiviral gene expression by N6-methyladenosine.
RNA m6A methylation orchestrates cancer growth and metastasis via macrophage reprogramming.
YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition.
METTL3 promotes tumour development by decreasing APC expression mediated by APC mRNA N6-methyladenosine-dependent YTHDF binding.
YTHDF1-regulated expression of TEAD1 contributes to the maintenance of intestinal stem cells.
N6-methyladenosine promotes induction of ADAR1-mediated A-to-I RNA editing to suppress aberrant antiviral innate immune responses.
Integrated analysis of m6A mRNA methylation in rats with monocrotaline-induced pulmonary arterial hypertension.
Epitranscriptomic editing of the RNA N6-methyladenosine modification by dCasRx conjugated methyltransferase and demethylase.
YTHDF1 Promotes Cyclin B1 Translation through m6A Modulation and Contributes to the Poor Prognosis of Lung Adenocarcinoma with KRAS/TP53 Co-Mutation.
Reprogramming of m6A epitranscriptome is crucial for shaping of transcriptome and proteome in response to hypoxia.
ALKBH5 suppresses tumor progression via an m6A-dependent epigenetic silencing of pre-miR-181b-1/YAP signaling axis in osteosarcoma.
Relaxed initiation pausing of ribosomes drives oncogenic translation.
m6A mRNA methylation regulates testosterone synthesis through modulating autophagy in Leydig cells.
HIF-1α-induced expression of m6A reader YTHDF1 drives hypoxia-induced autophagy and malignancy of hepatocellular carcinoma by promoting ATG2A and ATG14 translation.
METTL3-dependent N6-methyladenosine RNA modification mediates the atherogenic inflammatory cascades in vascular endothelium.
Endothelial METTL3 (Methyltransferase-Like 3) Inhibits Fibrinolysis by Promoting PAI-1 (Plasminogen Activator Inhibitor-1) Expression Through Enhancing Jun Proto-Oncogene N6-Methyladenosine Modification.
GR-mediated transcriptional regulation of m6A metabolic genes contributes to diet-induced fatty liver in hens.
m6A modification regulates lung fibroblast-to-myofibroblast transition through modulating KCNH6 mRNA translation.
METTL14 facilitates global genome repair and suppresses skin tumorigenesis.
N(6)-methyladenosine-binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decay.
Sevoflurane impairs m6A-mediated mRNA translation and leads to fine motor and cognitive deficits.
Enterovirus 2Apro Cleavage of the YTHDF m6A Readers Implicates YTHDF3 as a Mediator of Type I Interferon-Driven JAK/STAT Signaling.
m6A Reader YTHDC2 Promotes Radiotherapy Resistance of Nasopharyngeal Carcinoma via Activating IGF1R/AKT/S6 Signaling Axis.
m6A-binding YTHDF proteins promote stress granule formation.
YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways.
m(6) A RNA methyltransferases METTL3/14 regulate immune responses to anti-PD-1 therapy.
Context-dependent functional compensation between Ythdf m(6)A reader proteins.
Discovery of Widespread Host Protein Interactions with the Pre-replicated Genome of CHIKV Using VIR-CLASP.
A Unified Model for the Function of YTHDF Proteins in Regulating m6A-Modified mRNA.
ANKLE1 N6 -Methyladenosine-related variant is associated with colorectal cancer risk by maintaining the genomic stability.
YTH domain family 2 promotes lung cancer cell growth by facilitating 6-phosphogluconate dehydrogenase mRNA translation.
N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells.
Altered m6A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection.
Expression and Prognostic Significance of m6A-Related Genes in Lung Adenocarcinoma.
YTHDF1 Facilitates the Progression of Hepatocellular Carcinoma by Promoting FZD5 mRNA Translation in an m6A-Dependent Manner.
N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation.
Adenylate Kinase 4 Modulates the Resistance of Breast Cancer Cells to Tamoxifen through an m6A-Based Epitranscriptomic Mechanism.
Musashi-1 promotes cancer stem cell properties of glioblastoma cells via upregulation of YTHDF1.
Interplay of m6A and H3K27 trimethylation restrains inflammation during bacterial infection.
Epitranscriptomic N6-Methyladenosine Modification Is Required for Direct Lineage Reprogramming into Neurons.
Translational Repression of G3BP in Cancer and Germ Cells Suppresses Stress Granules and Enhances Stress Tolerance.
A novel N6-methyladenosine (m6A)-dependent fate decision for the lncRNA THOR.
N6-methyladenosine modification enables viral RNA to escape recognition by RNA sensor RIG-I.
METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice.
Long noncoding RNA pncRNA-D reduces cyclin D1 gene expression and arrests cell cycle through RNA m6A modification.
The m6A reader YTHDF1 promotes ovarian cancer progression via augmenting EIF3C translation.
G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules.
YTHDF1 Regulates Tumorigenicity and Cancer Stem Cell-Like Activity in Human Colorectal Carcinoma.
Viral N6-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus.
YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression.
The Tudor SND1 protein is an m6A RNA reader essential for replication of Kaposi's sarcoma-associated herpesvirus.
The m6A reader YTHDF1 regulates axon guidance through translational control of Robo3.1 expression.
CCR7 Chemokine Receptor-Inducible lnc-Dpf3 Restrains Dendritic Cell Migration by Inhibiting HIF-1α-Mediated Glycolysis.
Dynamic m6A mRNA methylation reveals the role of METTL3-m6A-CDCP1 signaling axis in chemical carcinogenesis.
m6A enhances the phase separation potential of mRNA.
Dual roles for the ER membrane protein complex in flavivirus infection: viral entry and protein biogenesis.
A novel m(6)A reader Prrc2a controls oligodendroglial specification and myelination.
N6-methyladenosine modification and METTL3 modulate enterovirus 71 replication.
Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells.
m6A modification controls the innate immune response to infection by targeting type I interferons.
m6A methylation controls pluripotency of porcine induced pluripotent stem cells by targeting SOCS3/JAK2/STAT3 pathway in a YTHDF1/YTHDF2-orchestrated manner.
Increased m6A methylation level is associated with the progression of human abdominal aortic aneurysm.
Reduced m6A modification predicts malignant phenotypes and augmented Wnt/PI3K-Akt signaling in gastric cancer.
m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer.
m6A facilitates hippocampus-dependent learning and memory through YTHDF1.
mRNA m6A plays opposite role in regulating UCP2 and PNPLA2 protein expression in adipocytes.
METTL3-mediated N6-methyladenosine mRNA modification enhances long-term memory consolidation.
Fragile X mental retardation protein modulates the stability of its m6A-marked messenger RNA targets.
Synaptic N6-methyladenosine (m6A) epitranscriptome reveals functional partitioning of localized transcripts.
Oncogene c-Myc promotes epitranscriptome m6A reader YTHDF1 expression in colorectal cancer.
Epitranscriptomic m6A Regulation of Axon Regeneration in the Adult Mammalian Nervous System.
RNA m6 A modification enzymes shape innate responses to DNA by regulating interferon β.
N6-methyladenosine modification and the YTHDF2 reader protein play cell type specific roles in lytic viral gene expression during Kaposi's sarcoma-associated herpesvirus infection.
YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA.
The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity.
N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection.
Wang H, Luo Q, Kang J, Wei Q, Yang Y, Yang D, Liu X, Liu T, Yi P
Frontiers in oncology 2021;11:650383
Frontiers in oncology 2021;11:650383
YTHDF1 and YTHDF2 are associated with better patient survival and an inflamed tumor-immune microenvironment in non-small-cell lung cancer.
Tsuchiya K, Yoshimura K, Inoue Y, Iwashita Y, Yamada H, Kawase A, Watanabe T, Tanahashi M, Ogawa H, Funai K, Shinmura K, Suda T, Sugimura H
Oncoimmunology 2021;10(1):1962656
Oncoimmunology 2021;10(1):1962656
Insufficient Radiofrequency Ablation Promotes Hepatocellular Carcinoma Metastasis Through N6-Methyladenosine mRNA Methylation-Dependent Mechanism.
Su T, Huang M, Liao J, Lin S, Yu P, Yang J, Cai Y, Zhu S, Xu L, Peng Z, Peng S, Chen S, Kuang M
Hepatology (Baltimore, Md.) 2021 Sep;74(3):1339-1356
Hepatology (Baltimore, Md.) 2021 Sep;74(3):1339-1356
Vitamin B12 Deficiency Dysregulates m6A mRNA Methylation of Genes Involved in Neurological Functions.
Mosca P, Robert A, Alberto JM, Meyer M, Kundu U, Hergalant S, Umoret R, Coelho D, Guéant JL, Leheup B, Dreumont N
Molecular nutrition & food research 2021 Sep;65(17):e2100206
Molecular nutrition & food research 2021 Sep;65(17):e2100206
Differential roles of YTHDF1 and YTHDF3 in embryonic stem cell-derived cardiomyocyte differentiation.
Wang S, Zhang J, Wu X, Lin X, Liu XM, Zhou J
RNA biology 2021 Sep;18(9):1354-1363
RNA biology 2021 Sep;18(9):1354-1363
METTL3-dependent RNA m6A dysregulation contributes to neurodegeneration in Alzheimer's disease through aberrant cell cycle events.
Zhao F, Xu Y, Gao S, Qin L, Austria Q, Siedlak SL, Pajdzik K, Dai Q, He C, Wang W, O'Donnell JM, Tang B, Zhu X
Molecular neurodegeneration 2021 Sep 30;16(1):70
Molecular neurodegeneration 2021 Sep 30;16(1):70
METTL3-m6A-Rubicon axis inhibits autophagy in nonalcoholic fatty liver disease.
Peng Z, Gong Y, Wang X, He W, Wu L, Zhang L, Xiong L, Huang Y, Su L, Shi P, Cao X, Liu R, Li Y, Xiao H
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Sep 20;
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Sep 20;
METTL3 regulates hippocampal gene transcription via N6-methyladenosine methylation in sevoflurane-induced postoperative cognitive dysfunction mouse.
He B, Wang J
Aging 2021 Oct 5;13(19):23108-23118
Aging 2021 Oct 5;13(19):23108-23118
Streptozotocin-Induced Astrocyte Mitochondrial Dysfunction Is Ameliorated by FTO Inhibitor MO-I-500.
Cockova Z, Honc O, Telensky P, Olsen MJ, Novotny J
ACS chemical neuroscience 2021 Oct 20;12(20):3818-3828
ACS chemical neuroscience 2021 Oct 20;12(20):3818-3828
The m6 A Readers YTHDF1 and YTHDF2 Synergistically Control Cerebellar Parallel Fiber Growth by Regulating Local Translation of the Key Wnt5a Signaling Components in Axons.
Yu J, She Y, Yang L, Zhuang M, Han P, Liu J, Lin X, Wang N, Chen M, Jiang C, Zhang Y, Yuan Y, Ji SJ
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Nov;8(22):e2101329
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Nov;8(22):e2101329
The pathological tissue expression pattern and clinical significance of m6A-regulatory genes in non-small cell lung cancer.
Li Y, Zhang X, Cai J, Ren L, Liu B, Wu M, Lu W, Li R, Zhang C, Huang C, Tong J, Liu A, Zheng Y, Ren D, Guo Y, Huang Y
The journal of gene medicine 2021 Nov 9;:e3397
The journal of gene medicine 2021 Nov 9;:e3397
Mettl3 promotes oxLDL-mediated inflammation through activating STAT1 signaling.
Li Z, Xu Q, Huangfu N, Chen X, Zhu J
Journal of clinical laboratory analysis 2021 Nov 26;:e24019
Journal of clinical laboratory analysis 2021 Nov 26;:e24019
Stabilization of UCA1 by N6-methyladenosine RNA methylation modification promotes colorectal cancer progression.
He RZ, Jiang J, Hu X, Lei M, Li J, Luo W, Duan L, Hu Z, Mo YY, Luo DX, Peng WX
Cancer cell international 2021 Nov 22;21(1):616
Cancer cell international 2021 Nov 22;21(1):616
The m6A "reader" YTHDF1 promotes osteogenesis of bone marrow mesenchymal stem cells through translational control of ZNF839.
Liu T, Zheng X, Wang C, Wang C, Jiang S, Li B, Chen P, Xu W, Zheng H, Yang R, Huang X, Zhang X, Jiang L
Cell death & disease 2021 Nov 12;12(11):1078
Cell death & disease 2021 Nov 12;12(11):1078
WNT/β-catenin-suppressed FTO expression increases m6A of c-Myc mRNA to promote tumor cell glycolysis and tumorigenesis.
Yang X, Shao F, Guo D, Wang W, Wang J, Zhu R, Gao Y, He J, Lu Z
Cell death & disease 2021 May 8;12(5):462
Cell death & disease 2021 May 8;12(5):462
Curcumin prevents obesity by targeting TRAF4-induced ubiquitylation in m6 A-dependent manner.
Chen Y, Wu R, Chen W, Liu Y, Liao X, Zeng B, Guo G, Lou F, Xiang Y, Wang Y, Wang X
EMBO reports 2021 May 5;22(5):e52146
EMBO reports 2021 May 5;22(5):e52146
YTHDF1 Promotes Gastric Carcinogenesis by Controlling Translation of FZD7.
Pi J, Wang W, Ji M, Wang X, Wei X, Jin J, Liu T, Qiang J, Qi Z, Li F, Liu Y, Ma Y, Si Y, Huo Y, Gao Y, Chen Y, Dong L, Su R, Chen J, Rao S, Yi P, Yu S, Wang F, Yu J
Cancer research 2021 May 15;81(10):2651-2665
Cancer research 2021 May 15;81(10):2651-2665
m6A RNA methylation regulates the fate of endogenous retroviruses.
Chelmicki T, Roger E, Teissandier A, Dura M, Bonneville L, Rucli S, Dossin F, Fouassier C, Lameiras S, Bourc'his D
Nature 2021 Mar;591(7849):312-316
Nature 2021 Mar;591(7849):312-316
Comparison of RNA m6A and DNA methylation profiles between mouse female germline stem cells and STO cells.
Zhao X, Tian GG, Fang Q, Pei X, Wang Z, Wu J
Molecular therapy. Nucleic acids 2021 Mar 5;23:431-439
Molecular therapy. Nucleic acids 2021 Mar 5;23:431-439
MYC promotes cancer progression by modulating m6 A modifications to suppress target gene translation.
Wu G, Suo C, Yang Y, Shen S, Sun L, Li ST, Zhou Y, Yang D, Wang Y, Cai Y, Wang N, Zhang H, Yang YG, Cao J, Gao P
EMBO reports 2021 Mar 3;22(3):e51519
EMBO reports 2021 Mar 3;22(3):e51519
Post-transcriptional regulation of antiviral gene expression by N6-methyladenosine.
McFadden MJ, McIntyre ABR, Mourelatos H, Abell NS, Gokhale NS, Ipas H, Xhemalçe B, Mason CE, Horner SM
Cell reports 2021 Mar 2;34(9):108798
Cell reports 2021 Mar 2;34(9):108798
RNA m6A methylation orchestrates cancer growth and metastasis via macrophage reprogramming.
Yin H, Zhang X, Yang P, Zhang X, Peng Y, Li D, Yu Y, Wu Y, Wang Y, Zhang J, Ding X, Wang X, Yang A, Zhang R
Nature communications 2021 Mar 2;12(1):1394
Nature communications 2021 Mar 2;12(1):1394
YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition.
Luo X, Cao M, Gao F, He X
Experimental hematology & oncology 2021 Jun 4;10(1):35
Experimental hematology & oncology 2021 Jun 4;10(1):35
METTL3 promotes tumour development by decreasing APC expression mediated by APC mRNA N6-methyladenosine-dependent YTHDF binding.
Wang W, Shao F, Yang X, Wang J, Zhu R, Yang Y, Zhao G, Guo D, Sun Y, Wang J, Xue Q, Gao S, Gao Y, He J, Lu Z
Nature communications 2021 Jun 21;12(1):3803
Nature communications 2021 Jun 21;12(1):3803
YTHDF1-regulated expression of TEAD1 contributes to the maintenance of intestinal stem cells.
Jiang D, Hou J, Qian Y, Gao Y, Gao X, Wei S
Biochemical and biophysical research communications 2021 Jun 11;557:85-89
Biochemical and biophysical research communications 2021 Jun 11;557:85-89
N6-methyladenosine promotes induction of ADAR1-mediated A-to-I RNA editing to suppress aberrant antiviral innate immune responses.
Terajima H, Lu M, Zhang L, Cui Q, Shi Y, Li J, He C
PLoS biology 2021 Jul;19(7):e3001292
PLoS biology 2021 Jul;19(7):e3001292
Integrated analysis of m6A mRNA methylation in rats with monocrotaline-induced pulmonary arterial hypertension.
Zeng Y, Huang T, Zuo W, Wang D, Xie Y, Wang X, Xiao Z, Chen Z, Liu Q, Liu N, Xiao Y
Aging 2021 Jul 26;13(14):18238-18256
Aging 2021 Jul 26;13(14):18238-18256
Epitranscriptomic editing of the RNA N6-methyladenosine modification by dCasRx conjugated methyltransferase and demethylase.
Xia Z, Tang M, Ma J, Zhang H, Gimple RC, Prager BC, Tang H, Sun C, Liu F, Lin P, Mei Y, Du R, Rich JN, Xie Q
Nucleic acids research 2021 Jul 21;49(13):7361-7374
Nucleic acids research 2021 Jul 21;49(13):7361-7374
YTHDF1 Promotes Cyclin B1 Translation through m6A Modulation and Contributes to the Poor Prognosis of Lung Adenocarcinoma with KRAS/TP53 Co-Mutation.
Lou X, Ning J, Liu W, Li K, Qian B, Xu D, Wu Y, Zhang D, Cui W
Cells 2021 Jul 2;10(7)
Cells 2021 Jul 2;10(7)
Reprogramming of m6A epitranscriptome is crucial for shaping of transcriptome and proteome in response to hypoxia.
Wang YJ, Yang B, Lai Q, Shi JF, Peng JY, Zhang Y, Hu KS, Li YQ, Peng JW, Yang ZZ, Li YT, Pan Y, Koeffler HP, Liao JY, Yin D
RNA biology 2021 Jan;18(1):131-143
RNA biology 2021 Jan;18(1):131-143
ALKBH5 suppresses tumor progression via an m6A-dependent epigenetic silencing of pre-miR-181b-1/YAP signaling axis in osteosarcoma.
Yuan Y, Yan G, He M, Lei H, Li L, Wang Y, He X, Li G, Wang Q, Gao Y, Qu Z, Mei Z, Shen Z, Pu J, Wang A, Zhao W, Jiang H, Du W, Yang L
Cell death & disease 2021 Jan 11;12(1):60
Cell death & disease 2021 Jan 11;12(1):60
Relaxed initiation pausing of ribosomes drives oncogenic translation.
Dong L, Mao Y, Zhou A, Liu XM, Zhou J, Wan J, Qian SB
Science advances 2021 Feb;7(8)
Science advances 2021 Feb;7(8)
m6A mRNA methylation regulates testosterone synthesis through modulating autophagy in Leydig cells.
Chen Y, Wang J, Xu D, Xiang Z, Ding J, Yang X, Li D, Han X
Autophagy 2021 Feb;17(2):457-475
Autophagy 2021 Feb;17(2):457-475
HIF-1α-induced expression of m6A reader YTHDF1 drives hypoxia-induced autophagy and malignancy of hepatocellular carcinoma by promoting ATG2A and ATG14 translation.
Li Q, Ni Y, Zhang L, Jiang R, Xu J, Yang H, Hu Y, Qiu J, Pu L, Tang J, Wang X
Signal transduction and targeted therapy 2021 Feb 23;6(1):76
Signal transduction and targeted therapy 2021 Feb 23;6(1):76
METTL3-dependent N6-methyladenosine RNA modification mediates the atherogenic inflammatory cascades in vascular endothelium.
Chien CS, Li JY, Chien Y, Wang ML, Yarmishyn AA, Tsai PH, Juan CC, Nguyen P, Cheng HM, Huo TI, Chiou SH, Chien S
Proceedings of the National Academy of Sciences of the United States of America 2021 Feb 16;118(7)
Proceedings of the National Academy of Sciences of the United States of America 2021 Feb 16;118(7)
Endothelial METTL3 (Methyltransferase-Like 3) Inhibits Fibrinolysis by Promoting PAI-1 (Plasminogen Activator Inhibitor-1) Expression Through Enhancing Jun Proto-Oncogene N6-Methyladenosine Modification.
Bai Q, Lu Y, Chen Y, Zhang H, Zhang W, Wu H, Wen A
Arteriosclerosis, thrombosis, and vascular biology 2021 Dec;41(12):2877-2889
Arteriosclerosis, thrombosis, and vascular biology 2021 Dec;41(12):2877-2889
GR-mediated transcriptional regulation of m6A metabolic genes contributes to diet-induced fatty liver in hens.
Feng Y, Li Y, Jiang W, Hu Y, Jia Y, Zhao R
Journal of animal science and biotechnology 2021 Dec 7;12(1):117
Journal of animal science and biotechnology 2021 Dec 7;12(1):117
m6A modification regulates lung fibroblast-to-myofibroblast transition through modulating KCNH6 mRNA translation.
Zhang JX, Huang PJ, Wang DP, Yang WY, Lu J, Zhu Y, Meng XX, Wu X, Lin QH, Lv H, Xie H, Wang RL
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Dec 1;29(12):3436-3448
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Dec 1;29(12):3436-3448
METTL14 facilitates global genome repair and suppresses skin tumorigenesis.
Yang Z, Yang S, Cui YH, Wei J, Shah P, Park G, Cui X, He C, He YY
Proceedings of the National Academy of Sciences of the United States of America 2021 Aug 31;118(35)
Proceedings of the National Academy of Sciences of the United States of America 2021 Aug 31;118(35)
N(6)-methyladenosine-binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decay.
Xia TL, Li X, Wang X, Zhu YJ, Zhang H, Cheng W, Chen ML, Ye Y, Li Y, Zhang A, Dai DL, Zhu QY, Yuan L, Zheng J, Huang H, Chen SQ, Xiao ZW, Wang HB, Roy G, Zhong Q, Lin D, Zeng YX, Wang J, Zhao B, Gewurz BE, Chen J, Zuo Z, Zeng MS
EMBO reports 2021 Apr 7;22(4):e50128
EMBO reports 2021 Apr 7;22(4):e50128
Sevoflurane impairs m6A-mediated mRNA translation and leads to fine motor and cognitive deficits.
Zhang L, Cheng Y, Xue Z, Li J, Wu N, Yan J, Wang J, Wang C, Chen W, Zhou T, Qiu Z, Jiang H
Cell biology and toxicology 2021 Apr 29;
Cell biology and toxicology 2021 Apr 29;
Enterovirus 2Apro Cleavage of the YTHDF m6A Readers Implicates YTHDF3 as a Mediator of Type I Interferon-Driven JAK/STAT Signaling.
Kastan JP, Tremblay MW, Brown MC, Trimarco JD, Dobrikova EY, Dobrikov MI, Gromeier M
mBio 2021 Apr 13;12(2)
mBio 2021 Apr 13;12(2)
m6A Reader YTHDC2 Promotes Radiotherapy Resistance of Nasopharyngeal Carcinoma via Activating IGF1R/AKT/S6 Signaling Axis.
He JJ, Li Z, Rong ZX, Gao J, Mu Y, Guan YD, Ren XX, Zi YY, Liu LY, Fan Q, Zhou M, Duan YM, Zhou Q, Deng YZ, Sun LQ
Frontiers in oncology 2020;10:1166
Frontiers in oncology 2020;10:1166
m6A-binding YTHDF proteins promote stress granule formation.
Fu Y, Zhuang X
Nature chemical biology 2020 Sep;16(9):955-963
Nature chemical biology 2020 Sep;16(9):955-963
YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways.
Liu J, Gao M, Xu S, Chen Y, Wu K, Liu H, Wang J, Yang X, Wang J, Liu W, Bao X, Chen J
Cell reports 2020 Sep 8;32(10):108120
Cell reports 2020 Sep 8;32(10):108120
m(6) A RNA methyltransferases METTL3/14 regulate immune responses to anti-PD-1 therapy.
Wang L, Hui H, Agrawal K, Kang Y, Li N, Tang R, Yuan J, Rana TM
The EMBO journal 2020 Oct 15;39(20):e104514
The EMBO journal 2020 Oct 15;39(20):e104514
Context-dependent functional compensation between Ythdf m(6)A reader proteins.
Lasman L, Krupalnik V, Viukov S, Mor N, Aguilera-Castrejon A, Schneir D, Bayerl J, Mizrahi O, Peles S, Tawil S, Sathe S, Nachshon A, Shani T, Zerbib M, Kilimnik I, Aigner S, Shankar A, Mueller JR, Schwartz S, Stern-Ginossar N, Yeo GW, Geula S, Novershtern N, Hanna JH
Genes & development 2020 Oct 1;34(19-20):1373-1391
Genes & development 2020 Oct 1;34(19-20):1373-1391
Discovery of Widespread Host Protein Interactions with the Pre-replicated Genome of CHIKV Using VIR-CLASP.
Kim B, Arcos S, Rothamel K, Jian J, Rose KL, McDonald WH, Bian Y, Reasoner S, Barrows NJ, Bradrick S, Garcia-Blanco MA, Ascano M
Molecular cell 2020 May 21;78(4):624-640.e7
Molecular cell 2020 May 21;78(4):624-640.e7
A Unified Model for the Function of YTHDF Proteins in Regulating m6A-Modified mRNA.
Zaccara S, Jaffrey SR
Cell 2020 Jun 25;181(7):1582-1595.e18
Cell 2020 Jun 25;181(7):1582-1595.e18
ANKLE1 N6 -Methyladenosine-related variant is associated with colorectal cancer risk by maintaining the genomic stability.
Tian J, Ying P, Ke J, Zhu Y, Yang Y, Gong Y, Zou D, Peng X, Yang N, Wang X, Mei S, Zhang Y, Wang C, Zhong R, Chang J, Miao X
International journal of cancer 2020 Jun 15;146(12):3281-3293
International journal of cancer 2020 Jun 15;146(12):3281-3293
YTH domain family 2 promotes lung cancer cell growth by facilitating 6-phosphogluconate dehydrogenase mRNA translation.
Sheng H, Li Z, Su S, Sun W, Zhang X, Li L, Li J, Liu S, Lu B, Zhang S, Shan C
Carcinogenesis 2020 Jul 10;41(5):541-550
Carcinogenesis 2020 Jul 10;41(5):541-550
N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells.
Abakir A, Giles TC, Cristini A, Foster JM, Dai N, Starczak M, Rubio-Roldan A, Li M, Eleftheriou M, Crutchley J, Flatt L, Young L, Gaffney DJ, Denning C, Dalhus B, Emes RD, Gackowski D, Corrêa IR Jr, Garcia-Perez JL, Klungland A, Gromak N, Ruzov A
Nature genetics 2020 Jan;52(1):48-55
Nature genetics 2020 Jan;52(1):48-55
Altered m6A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection.
Gokhale NS, McIntyre ABR, Mattocks MD, Holley CL, Lazear HM, Mason CE, Horner SM
Molecular cell 2020 Feb 6;77(3):542-555.e8
Molecular cell 2020 Feb 6;77(3):542-555.e8
Expression and Prognostic Significance of m6A-Related Genes in Lung Adenocarcinoma.
Zhang Y, Liu X, Liu L, Li J, Hu Q, Sun R
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 22;26:e919644
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 22;26:e919644
YTHDF1 Facilitates the Progression of Hepatocellular Carcinoma by Promoting FZD5 mRNA Translation in an m6A-Dependent Manner.
Liu X, Qin J, Gao T, Li C, He B, Pan B, Xu X, Chen X, Zeng K, Xu M, Zhu C, Pan Y, Sun H, Sun L, Xu T, Wang S
Molecular therapy. Nucleic acids 2020 Dec 4;22:750-765
Molecular therapy. Nucleic acids 2020 Dec 4;22:750-765
N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation.
Du J, Liao W, Liu W, Deb DK, He L, Hsu PJ, Nguyen T, Zhang L, Bissonnette M, He C, Li YC
Developmental cell 2020 Dec 21;55(6):737-753.e7
Developmental cell 2020 Dec 21;55(6):737-753.e7
Adenylate Kinase 4 Modulates the Resistance of Breast Cancer Cells to Tamoxifen through an m6A-Based Epitranscriptomic Mechanism.
Liu X, Gonzalez G, Dai X, Miao W, Yuan J, Huang M, Bade D, Li L, Sun Y, Wang Y
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Dec 2;28(12):2593-2604
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Dec 2;28(12):2593-2604
Musashi-1 promotes cancer stem cell properties of glioblastoma cells via upregulation of YTHDF1.
Yarmishyn AA, Yang YP, Lu KH, Chen YC, Chien Y, Chou SJ, Tsai PH, Ma HI, Chien CS, Chen MT, Wang ML
Cancer cell international 2020 Dec 14;20(1):597
Cancer cell international 2020 Dec 14;20(1):597
Interplay of m6A and H3K27 trimethylation restrains inflammation during bacterial infection.
Wu C, Chen W, He J, Jin S, Liu Y, Yi Y, Gao Z, Yang J, Yang J, Cui J, Zhao W
Science advances 2020 Aug;6(34):eaba0647
Science advances 2020 Aug;6(34):eaba0647
Epitranscriptomic N6-Methyladenosine Modification Is Required for Direct Lineage Reprogramming into Neurons.
Choi H, Baek S, Cho B, Kim S, Kim J, Chang Y, Shin J, Kim J
ACS chemical biology 2020 Aug 21;15(8):2087-2097
ACS chemical biology 2020 Aug 21;15(8):2087-2097
Translational Repression of G3BP in Cancer and Germ Cells Suppresses Stress Granules and Enhances Stress Tolerance.
Lee AK, Klein J, Fon Tacer K, Lord T, Oatley MJ, Oatley JM, Porter SN, Pruett-Miller SM, Tikhonova EB, Karamyshev AL, Wang YD, Yang P, Korff A, Kim HJ, Taylor JP, Potts PR
Molecular cell 2020 Aug 20;79(4):645-659.e9
Molecular cell 2020 Aug 20;79(4):645-659.e9
A novel N6-methyladenosine (m6A)-dependent fate decision for the lncRNA THOR.
Liu H, Xu Y, Yao B, Sui T, Lai L, Li Z
Cell death & disease 2020 Aug 13;11(8):613
Cell death & disease 2020 Aug 13;11(8):613
N6-methyladenosine modification enables viral RNA to escape recognition by RNA sensor RIG-I.
Lu M, Zhang Z, Xue M, Zhao BS, Harder O, Li A, Liang X, Gao TZ, Xu Y, Zhou J, Feng Z, Niewiesk S, Peeples ME, He C, Li J
Nature microbiology 2020 Apr;5(4):584-598
Nature microbiology 2020 Apr;5(4):584-598
METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice.
Wang Y, Gao M, Zhu F, Li X, Yang Y, Yan Q, Jia L, Xie L, Chen Z
Nature communications 2020 Apr 3;11(1):1648
Nature communications 2020 Apr 3;11(1):1648
Long noncoding RNA pncRNA-D reduces cyclin D1 gene expression and arrests cell cycle through RNA m6A modification.
Yoneda R, Ueda N, Uranishi K, Hirasaki M, Kurokawa R
The Journal of biological chemistry 2020 Apr 24;295(17):5626-5639
The Journal of biological chemistry 2020 Apr 24;295(17):5626-5639
The m6A reader YTHDF1 promotes ovarian cancer progression via augmenting EIF3C translation.
Liu T, Wei Q, Jin J, Luo Q, Liu Y, Yang Y, Cheng C, Li L, Pi J, Si Y, Xiao H, Li L, Rao S, Wang F, Yu J, Yu J, Zou D, Yi P
Nucleic acids research 2020 Apr 17;48(7):3816-3831
Nucleic acids research 2020 Apr 17;48(7):3816-3831
G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules.
Yang P, Mathieu C, Kolaitis RM, Zhang P, Messing J, Yurtsever U, Yang Z, Wu J, Li Y, Pan Q, Yu J, Martin EW, Mittag T, Kim HJ, Taylor JP
Cell 2020 Apr 16;181(2):325-345.e28
Cell 2020 Apr 16;181(2):325-345.e28
YTHDF1 Regulates Tumorigenicity and Cancer Stem Cell-Like Activity in Human Colorectal Carcinoma.
Bai Y, Yang C, Wu R, Huang L, Song S, Li W, Yan P, Lin C, Li D, Zhang Y
Frontiers in oncology 2019;9:332
Frontiers in oncology 2019;9:332
Viral N6-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus.
Xue M, Zhao BS, Zhang Z, Lu M, Harder O, Chen P, Lu Z, Li A, Ma Y, Xu Y, Liang X, Zhou J, Niewiesk S, Peeples ME, He C, Li J
Nature communications 2019 Oct 9;10(1):4595
Nature communications 2019 Oct 9;10(1):4595
YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression.
Shi Y, Fan S, Wu M, Zuo Z, Li X, Jiang L, Shen Q, Xu P, Zeng L, Zhou Y, Huang Y, Yang Z, Zhou J, Gao J, Zhou H, Xu S, Ji H, Shi P, Wu DD, Yang C, Chen Y
Nature communications 2019 Oct 25;10(1):4892
Nature communications 2019 Oct 25;10(1):4892
The Tudor SND1 protein is an m6A RNA reader essential for replication of Kaposi's sarcoma-associated herpesvirus.
Baquero-Perez B, Antanaviciute A, Yonchev ID, Carr IM, Wilson SA, Whitehouse A
eLife 2019 Oct 24;8
eLife 2019 Oct 24;8
The m6A reader YTHDF1 regulates axon guidance through translational control of Robo3.1 expression.
Zhuang M, Li X, Zhu J, Zhang J, Niu F, Liang F, Chen M, Li D, Han P, Ji SJ
Nucleic acids research 2019 May 21;47(9):4765-4777
Nucleic acids research 2019 May 21;47(9):4765-4777
CCR7 Chemokine Receptor-Inducible lnc-Dpf3 Restrains Dendritic Cell Migration by Inhibiting HIF-1α-Mediated Glycolysis.
Liu J, Zhang X, Chen K, Cheng Y, Liu S, Xia M, Chen Y, Zhu H, Li Z, Cao X
Immunity 2019 Mar 19;50(3):600-615.e15
Immunity 2019 Mar 19;50(3):600-615.e15
Dynamic m6A mRNA methylation reveals the role of METTL3-m6A-CDCP1 signaling axis in chemical carcinogenesis.
Yang F, Jin H, Que B, Chao Y, Zhang H, Ying X, Zhou Z, Yuan Z, Su J, Wu B, Zhang W, Qi D, Chen D, Min W, Lin S, Ji W
Oncogene 2019 Jun;38(24):4755-4772
Oncogene 2019 Jun;38(24):4755-4772
m6A enhances the phase separation potential of mRNA.
Ries RJ, Zaccara S, Klein P, Olarerin-George A, Namkoong S, Pickering BF, Patil DP, Kwak H, Lee JH, Jaffrey SR
Nature 2019 Jul;571(7765):424-428
Nature 2019 Jul;571(7765):424-428
Dual roles for the ER membrane protein complex in flavivirus infection: viral entry and protein biogenesis.
Barrows NJ, Anglero-Rodriguez Y, Kim B, Jamison SF, Le Sommer C, McGee CE, Pearson JL, Dimopoulos G, Ascano M, Bradrick SS, Garcia-Blanco MA
Scientific reports 2019 Jul 4;9(1):9711
Scientific reports 2019 Jul 4;9(1):9711
A novel m(6)A reader Prrc2a controls oligodendroglial specification and myelination.
Wu R, Li A, Sun B, Sun JG, Zhang J, Zhang T, Chen Y, Xiao Y, Gao Y, Zhang Q, Ma J, Yang X, Liao Y, Lai WY, Qi X, Wang S, Shu Y, Wang HL, Wang F, Yang YG, Yuan Z
Cell research 2019 Jan;29(1):23-41
Cell research 2019 Jan;29(1):23-41
N6-methyladenosine modification and METTL3 modulate enterovirus 71 replication.
Hao H, Hao S, Chen H, Chen Z, Zhang Y, Wang J, Wang H, Zhang B, Qiu J, Deng F, Guan W
Nucleic acids research 2019 Jan 10;47(1):362-374
Nucleic acids research 2019 Jan 10;47(1):362-374
Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells.
Han D, Liu J, Chen C, Dong L, Liu Y, Chang R, Huang X, Liu Y, Wang J, Dougherty U, Bissonnette MB, Shen B, Weichselbaum RR, Xu MM, He C
Nature 2019 Feb;566(7743):270-274
Nature 2019 Feb;566(7743):270-274
m6A modification controls the innate immune response to infection by targeting type I interferons.
Winkler R, Gillis E, Lasman L, Safra M, Geula S, Soyris C, Nachshon A, Tai-Schmiedel J, Friedman N, Le-Trilling VTK, Trilling M, Mandelboim M, Hanna JH, Schwartz S, Stern-Ginossar N
Nature immunology 2019 Feb;20(2):173-182
Nature immunology 2019 Feb;20(2):173-182
m6A methylation controls pluripotency of porcine induced pluripotent stem cells by targeting SOCS3/JAK2/STAT3 pathway in a YTHDF1/YTHDF2-orchestrated manner.
Wu R, Liu Y, Zhao Y, Bi Z, Yao Y, Liu Q, Wang F, Wang Y, Wang X
Cell death & disease 2019 Feb 20;10(3):171
Cell death & disease 2019 Feb 20;10(3):171
Increased m6A methylation level is associated with the progression of human abdominal aortic aneurysm.
He Y, Xing J, Wang S, Xin S, Han Y, Zhang J
Annals of translational medicine 2019 Dec;7(24):797
Annals of translational medicine 2019 Dec;7(24):797
Reduced m6A modification predicts malignant phenotypes and augmented Wnt/PI3K-Akt signaling in gastric cancer.
Zhang C, Zhang M, Ge S, Huang W, Lin X, Gao J, Gong J, Shen L
Cancer medicine 2019 Aug;8(10):4766-4781
Cancer medicine 2019 Aug;8(10):4766-4781
m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer.
Liu J, Eckert MA, Harada BT, Liu SM, Lu Z, Yu K, Tienda SM, Chryplewicz A, Zhu AC, Yang Y, Huang JT, Chen SM, Xu ZG, Leng XH, Yu XC, Cao J, Zhang Z, Liu J, Lengyel E, He C
Nature cell biology 2018 Sep;20(9):1074-1083
Nature cell biology 2018 Sep;20(9):1074-1083
m6A facilitates hippocampus-dependent learning and memory through YTHDF1.
Shi H, Zhang X, Weng YL, Lu Z, Liu Y, Lu Z, Li J, Hao P, Zhang Y, Zhang F, Wu Y, Delgado JY, Su Y, Patel MJ, Cao X, Shen B, Huang X, Ming GL, Zhuang X, Song H, He C, Zhou T
Nature 2018 Nov;563(7730):249-253
Nature 2018 Nov;563(7730):249-253
mRNA m6A plays opposite role in regulating UCP2 and PNPLA2 protein expression in adipocytes.
Wang X, Sun B, Jiang Q, Wu R, Cai M, Yao Y, Liu Q, Shi H, Feng J, Wang Y
International journal of obesity (2005) 2018 Nov;42(11):1912-1924
International journal of obesity (2005) 2018 Nov;42(11):1912-1924
METTL3-mediated N6-methyladenosine mRNA modification enhances long-term memory consolidation.
Zhang Z, Wang M, Xie D, Huang Z, Zhang L, Yang Y, Ma D, Li W, Zhou Q, Yang YG, Wang XJ
Cell research 2018 Nov;28(11):1050-1061
Cell research 2018 Nov;28(11):1050-1061
Fragile X mental retardation protein modulates the stability of its m6A-marked messenger RNA targets.
Zhang F, Kang Y, Wang M, Li Y, Xu T, Yang W, Song H, Wu H, Shu Q, Jin P
Human molecular genetics 2018 Nov 15;27(22):3936-3950
Human molecular genetics 2018 Nov 15;27(22):3936-3950
Synaptic N6-methyladenosine (m6A) epitranscriptome reveals functional partitioning of localized transcripts.
Merkurjev D, Hong WT, Iida K, Oomoto I, Goldie BJ, Yamaguti H, Ohara T, Kawaguchi SY, Hirano T, Martin KC, Pellegrini M, Wang DO
Nature neuroscience 2018 Jul;21(7):1004-1014
Nature neuroscience 2018 Jul;21(7):1004-1014
Oncogene c-Myc promotes epitranscriptome m6A reader YTHDF1 expression in colorectal cancer.
Nishizawa Y, Konno M, Asai A, Koseki J, Kawamoto K, Miyoshi N, Takahashi H, Nishida N, Haraguchi N, Sakai D, Kudo T, Hata T, Matsuda C, Mizushima T, Satoh T, Doki Y, Mori M, Ishii H
Oncotarget 2018 Jan 26;9(7):7476-7486
Oncotarget 2018 Jan 26;9(7):7476-7486
Epitranscriptomic m6A Regulation of Axon Regeneration in the Adult Mammalian Nervous System.
Weng YL, Wang X, An R, Cassin J, Vissers C, Liu Y, Liu Y, Xu T, Wang X, Wong SZH, Joseph J, Dore LC, Dong Q, Zheng W, Jin P, Wu H, Shen B, Zhuang X, He C, Liu K, Song H, Ming GL
Neuron 2018 Jan 17;97(2):313-325.e6
Neuron 2018 Jan 17;97(2):313-325.e6
RNA m6 A modification enzymes shape innate responses to DNA by regulating interferon β.
Rubio RM, Depledge DP, Bianco C, Thompson L, Mohr I
Genes & development 2018 Dec 1;32(23-24):1472-1484
Genes & development 2018 Dec 1;32(23-24):1472-1484
N6-methyladenosine modification and the YTHDF2 reader protein play cell type specific roles in lytic viral gene expression during Kaposi's sarcoma-associated herpesvirus infection.
Hesser CR, Karijolich J, Dominissini D, He C, Glaunsinger BA
PLoS pathogens 2018 Apr;14(4):e1006995
PLoS pathogens 2018 Apr;14(4):e1006995
YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA.
Shi H, Wang X, Lu Z, Zhao BS, Ma H, Hsu PJ, Liu C, He C
Cell research 2017 Mar;27(3):315-328
Cell research 2017 Mar;27(3):315-328
The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity.
Simsek D, Tiu GC, Flynn RA, Byeon GW, Leppek K, Xu AF, Chang HY, Barna M
Cell 2017 Jun 1;169(6):1051-1065.e18
Cell 2017 Jun 1;169(6):1051-1065.e18
N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection.
Gokhale NS, McIntyre ABR, McFadden MJ, Roder AE, Kennedy EM, Gandara JA, Hopcraft SE, Quicke KM, Vazquez C, Willer J, Ilkayeva OR, Law BA, Holley CL, Garcia-Blanco MA, Evans MJ, Suthar MS, Bradrick SS, Mason CE, Horner SM
Cell host & microbe 2016 Nov 9;20(5):654-665
Cell host & microbe 2016 Nov 9;20(5):654-665
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 17479-1-AP(YTHDF1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 17479-1-AP(YTHDF1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The YTHDF1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human YTHDF1. This antibody recognizes human, mouse, rat antigen. The YTHDF1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.