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- Antigen structure
- References [20]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- 51002-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#51002-1-AP, RRID:AB_2130516
- Product name
- hIST1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated hIST1 antibody (Cat. #51002-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CDK1 controls CHMP7-dependent nuclear envelope reformation.
AKTIP interacts with ESCRT I and is needed for the recruitment of ESCRT III subunits to the midbody.
ESCRT-III-associated proteins and spastin inhibit protrudin-dependent polarised membrane traffic.
De Novo VPS4A Mutations Cause Multisystem Disease with Abnormal Neurodevelopment.
Studying the Spatial Organization of ESCRTs in Cytokinetic Abscission Using the High-Resolution Imaging Techniques SIM and Cryo-SXT.
Regulation of OLC1 protein expression by the anaphase-promoting complex.
Nuclear envelope assembly defects link mitotic errors to chromothripsis.
VPS4 is a dynamic component of the centrosome that regulates centrosome localization of γ-tubulin, centriolar satellite stability and ciliogenesis.
Resolving ESCRT-III Spirals at the Intercellular Bridge of Dividing Cells Using 3D STORM.
Defects in ER-endosome contacts impact lysosome function in hereditary spastic paraplegia.
An Automated Image Analysis System to Quantify Endosomal Tubulation.
ALIX and ESCRT-I/II function as parallel ESCRT-III recruiters in cytokinetic abscission.
Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing.
Over-expression of the overexpressed in lung cancer-1 is associated with poor prognosis in colorectal cancer.
Over-expression of the overexpressed in lung cancer 1 is associated with poor prognosis in epithelial ovarian cancer.
An ESCRT-spastin interaction promotes fission of recycling tubules from the endosome.
ESCRT-III binding protein MITD1 is involved in cytokinesis and has an unanticipated PLD fold that binds membranes.
The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domain.
Cigarette smoke suppresses the ubiquitin-dependent degradation of OLC1.
Essential role of hIST1 in cytokinesis.
Gatta AT, Olmos Y, Stoten CL, Chen Q, Rosenthal PB, Carlton JG
eLife 2021 Jul 21;10
eLife 2021 Jul 21;10
AKTIP interacts with ESCRT I and is needed for the recruitment of ESCRT III subunits to the midbody.
Merigliano C, Burla R, La Torre M, Del Giudice S, Teo H, Liew CW, Chojnowski A, Goh WI, Olmos Y, Maccaroni K, Giubettini M, Chiolo I, Carlton JG, Raimondo D, Vernì F, Stewart CL, Rhodes D, Wright GD, Burke BE, Saggio I
PLoS genetics 2021 Aug;17(8):e1009757
PLoS genetics 2021 Aug;17(8):e1009757
ESCRT-III-associated proteins and spastin inhibit protrudin-dependent polarised membrane traffic.
Connell JW, Allison RJ, Rodger CE, Pearson G, Zlamalova E, Reid E
Cellular and molecular life sciences : CMLS 2020 Jul;77(13):2641-2658
Cellular and molecular life sciences : CMLS 2020 Jul;77(13):2641-2658
De Novo VPS4A Mutations Cause Multisystem Disease with Abnormal Neurodevelopment.
Rodger C, Flex E, Allison RJ, Sanchis-Juan A, Hasenahuer MA, Cecchetti S, French CE, Edgar JR, Carpentieri G, Ciolfi A, Pantaleoni F, Bruselles A, Genomics England Research Consortium, Onesimo R, Zampino G, Marcon F, Siniscalchi E, Lees M, Krishnakumar D, McCann E, Yosifova D, Jarvis J, Kruer MC, Marks W, Campbell J, Allen LE, Gustincich S, Raymond FL, Tartaglia M, Reid E
American journal of human genetics 2020 Dec 3;107(6):1129-1148
American journal of human genetics 2020 Dec 3;107(6):1129-1148
Studying the Spatial Organization of ESCRTs in Cytokinetic Abscission Using the High-Resolution Imaging Techniques SIM and Cryo-SXT.
Adar-Levor S, Goliand I, Elbaum M, Elia N
Methods in molecular biology (Clifton, N.J.) 2019;1998:129-148
Methods in molecular biology (Clifton, N.J.) 2019;1998:129-148
Regulation of OLC1 protein expression by the anaphase-promoting complex.
Zhang X, Chen W, Yin N, Dong L, Fu M, Zhan Q, Tong T
Oncology letters 2019 Mar;17(3):2639-2646
Oncology letters 2019 Mar;17(3):2639-2646
Nuclear envelope assembly defects link mitotic errors to chromothripsis.
Liu S, Kwon M, Mannino M, Yang N, Renda F, Khodjakov A, Pellman D
Nature 2018 Sep;561(7724):551-555
Nature 2018 Sep;561(7724):551-555
VPS4 is a dynamic component of the centrosome that regulates centrosome localization of γ-tubulin, centriolar satellite stability and ciliogenesis.
Ott C, Nachmias D, Adar S, Jarnik M, Sherman S, Birnbaum RY, Lippincott-Schwartz J, Elia N
Scientific reports 2018 Feb 20;8(1):3353
Scientific reports 2018 Feb 20;8(1):3353
Resolving ESCRT-III Spirals at the Intercellular Bridge of Dividing Cells Using 3D STORM.
Goliand I, Adar-Levor S, Segal I, Nachmias D, Dadosh T, Kozlov MM, Elia N
Cell reports 2018 Aug 14;24(7):1756-1764
Cell reports 2018 Aug 14;24(7):1756-1764
Defects in ER-endosome contacts impact lysosome function in hereditary spastic paraplegia.
Allison R, Edgar JR, Pearson G, Rizo T, Newton T, Günther S, Berner F, Hague J, Connell JW, Winkler J, Lippincott-Schwartz J, Beetz C, Winner B, Reid E
The Journal of cell biology 2017 May 1;216(5):1337-1355
The Journal of cell biology 2017 May 1;216(5):1337-1355
An Automated Image Analysis System to Quantify Endosomal Tubulation.
Newton TM, Reid E
PloS one 2016;11(12):e0168294
PloS one 2016;11(12):e0168294
ALIX and ESCRT-I/II function as parallel ESCRT-III recruiters in cytokinetic abscission.
Christ L, Wenzel EM, Liestøl K, Raiborg C, Campsteijn C, Stenmark H
The Journal of cell biology 2016 Feb 29;212(5):499-513
The Journal of cell biology 2016 Feb 29;212(5):499-513
Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing.
Vietri M, Schink KO, Campsteijn C, Wegner CS, Schultz SW, Christ L, Thoresen SB, Brech A, Raiborg C, Stenmark H
Nature 2015 Jun 11;522(7555):231-5
Nature 2015 Jun 11;522(7555):231-5
Over-expression of the overexpressed in lung cancer-1 is associated with poor prognosis in colorectal cancer.
Liu J, Song H, Yao L, Liu Y, Zhang Y, Zhao H, Ji H, Wang Y
Anticancer research 2014 Jan;34(1):367-72
Anticancer research 2014 Jan;34(1):367-72
Over-expression of the overexpressed in lung cancer 1 is associated with poor prognosis in epithelial ovarian cancer.
Jia C, Li X, Sun H, Sui L
Journal of surgical oncology 2013 Jun;107(8):847-52
Journal of surgical oncology 2013 Jun;107(8):847-52
An ESCRT-spastin interaction promotes fission of recycling tubules from the endosome.
Allison R, Lumb JH, Fassier C, Connell JW, Ten Martin D, Seaman MN, Hazan J, Reid E
The Journal of cell biology 2013 Aug 5;202(3):527-43
The Journal of cell biology 2013 Aug 5;202(3):527-43
ESCRT-III binding protein MITD1 is involved in cytokinesis and has an unanticipated PLD fold that binds membranes.
Hadders MA, Agromayor M, Obita T, Perisic O, Caballe A, Kloc M, Lamers MH, Williams RL, Martin-Serrano J
Proceedings of the National Academy of Sciences of the United States of America 2012 Oct 23;109(43):17424-9
Proceedings of the National Academy of Sciences of the United States of America 2012 Oct 23;109(43):17424-9
The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domain.
Agromayor M, Soler N, Caballe A, Kueck T, Freund SM, Allen MD, Bycroft M, Perisic O, Ye Y, McDonald B, Scheel H, Hofmann K, Neil SJ, Martin-Serrano J, Williams RL
Structure (London, England : 1993) 2012 Mar 7;20(3):414-28
Structure (London, England : 1993) 2012 Mar 7;20(3):414-28
Cigarette smoke suppresses the ubiquitin-dependent degradation of OLC1.
Zhang X, Xiao T, Cheng S, Tong T, Gao Y
Biochemical and biophysical research communications 2011 Apr 22;407(4):753-7
Biochemical and biophysical research communications 2011 Apr 22;407(4):753-7
Essential role of hIST1 in cytokinesis.
Agromayor M, Carlton JG, Phelan JP, Matthews DR, Carlin LM, Ameer-Beg S, Bowers K, Martin-Serrano J
Molecular biology of the cell 2009 Mar;20(5):1374-87
Molecular biology of the cell 2009 Mar;20(5):1374-87
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 51002-1-AP(hIST1 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using KIAA0174 antibody 51002-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung cancer using 51002-1-AP(hIST1 antibody) at dilution of 1:200 (under 40x lens)
- Sample type
- tissue
