BS2871

antibody from Bioworld Technology, Inc
Targeting: CTPS1 CTPS, GATD5
Provider product page for BS2871
Western blot
Immunohistochemistry

Antibody data

Product number
BS2871 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CTPS (K109) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 80-130 of Human CTPS.
Description
CTPS (cytidine-5-prime-triphosphate synthase) is a 591 amino acid protein that contains one glutamine amidotransferase type-1 domain and is involved in pyrimidine metabolism. CTPS catalyzes the ATP-dependent conversion of UTP to CTP, a rate-limiting reaction that requires either ammonia or L-glutamine as a nitrogen source. Via its catalytic activity, CTPS plays an important role in the synthesis of nucleic acids and is crucial for proper cell growth and development. The function of CTPS is regulated by a variety of mechanisms, including phosphorylation by protein kinase C (PKC), an event that can either stimulate or inhibit CTPS activity. The gene encoding CTPS is located in a region on chromosome 1 that is often associated with the progression of several tumor types, suggesting a possible role for CTPS in tumorigenesis.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CTPS1 protein structure - BS2871 shown in red.