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- Antibody Data
- Antigen structure
- References [15]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 21090-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21090-1-AP, RRID:AB_10734583
- Product name
- CHCHD4 antibody
- Antibody type
- Polyclonal
- Description
- CHCHD4 antibody (Cat. #21090-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Serine palmitoyltransferase assembles at ER-mitochondria contact sites.
Moschamindole induces glioma cell apoptosis by blocking Mia40-dependent mitochondrial intermembrane space assembly and oxidative respiration.
Bisphenol-A inhibits mitochondrial biogenesis via impairment of GFER mediated mitochondrial protein import in the rat brain hippocampus.
Augmenter of liver regeneration regulates cellular iron homeostasis by modulating mitochondrial transport of ATP-binding cassette B8.
Dependence of PINK1 accumulation on mitochondrial redox system.
Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal.
CHTM1 regulates cancer cell sensitivity to metabolic stress via p38-AIF1 pathway.
A novel CHCHD10 mutation implicates a Mia40-dependent mitochondrial import deficit in ALS.
A disease-associated Aifm1 variant induces severe myopathy in knockin mice.
CHTM1, a novel metabolic marker deregulated in human malignancies.
Quantitative proteomics in Friedreich's ataxia B-lymphocytes: A valuable approach to decipher the biochemical events responsible for pathogenesis.
Altered redox mitochondrial biology in the neurodegenerative disorder fragile X-tremor/ataxia syndrome: use of antioxidants in precision medicine.
The Level of ALR is Regulated by the Quantity of Mitochondrial DNA.
Loss of apoptosis-inducing factor critically affects MIA40 function.
MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.
Aaltonen MJ, Alecu I, König T, Bennett SA, Shoubridge EA
Life science alliance 2022 Feb;5(2)
Life science alliance 2022 Feb;5(2)
Moschamindole induces glioma cell apoptosis by blocking Mia40-dependent mitochondrial intermembrane space assembly and oxidative respiration.
Huang GD, Chen FF, Yang JH, Ma GX, Liao ZJ, Li WP, Li ZY, Chen L
Phytotherapy research : PTR 2021 Jun;35(6):3390-3405
Phytotherapy research : PTR 2021 Jun;35(6):3390-3405
Bisphenol-A inhibits mitochondrial biogenesis via impairment of GFER mediated mitochondrial protein import in the rat brain hippocampus.
Goyal S, Tiwari S, Seth B, Tandon A, Shankar J, Sinha M, Singh SJ, Priya S, Chaturvedi RK
Neurotoxicology 2021 Jul;85:18-32
Neurotoxicology 2021 Jul;85:18-32
Augmenter of liver regeneration regulates cellular iron homeostasis by modulating mitochondrial transport of ATP-binding cassette B8.
Chang HC, Shapiro JS, Jiang X, Senyei G, Sato T, Geier J, Sawicki KT, Ardehali H
eLife 2021 Apr 9;10
eLife 2021 Apr 9;10
Dependence of PINK1 accumulation on mitochondrial redox system.
Gao F, Zhang Y, Hou X, Tao Z, Ren H, Wang G
Aging cell 2020 Sep;19(9):e13211
Aging cell 2020 Sep;19(9):e13211
Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal.
Singh RP, Jeyaraju DV, Voisin V, Hurren R, Xu C, Hawley JR, Barghout SH, Khan DH, Gronda M, Wang X, Jitkova Y, Sharon D, Liyanagae S, MacLean N, Seneviratene AK, Mirali S, Borenstein A, Thomas GE, Soriano J, Orouji E, Minden MD, Arruda A, Chan SM, Bader GD, Lupien M, Schimmer AD
Cell stem cell 2020 Jun 4;26(6):926-937.e10
Cell stem cell 2020 Jun 4;26(6):926-937.e10
CHTM1 regulates cancer cell sensitivity to metabolic stress via p38-AIF1 pathway.
Babbar M, Huang Y, Curtiss CM, Sheikh MS
Journal of experimental & clinical cancer research : CR 2019 Jun 20;38(1):271
Journal of experimental & clinical cancer research : CR 2019 Jun 20;38(1):271
A novel CHCHD10 mutation implicates a Mia40-dependent mitochondrial import deficit in ALS.
Lehmer C, Schludi MH, Ransom L, Greiling J, Junghänel M, Exner N, Riemenschneider H, van der Zee J, Van Broeckhoven C, Weydt P, Heneka MT, Edbauer D
EMBO molecular medicine 2018 Jun;10(6)
EMBO molecular medicine 2018 Jun;10(6)
A disease-associated Aifm1 variant induces severe myopathy in knockin mice.
Wischhof L, Gioran A, Sonntag-Bensch D, Piazzesi A, Stork M, Nicotera P, Bano D
Molecular metabolism 2018 Jul;13:10-23
Molecular metabolism 2018 Jul;13:10-23
CHTM1, a novel metabolic marker deregulated in human malignancies.
Babbar M, Huang Y, An J, Landas SK, Sheikh MS
Oncogene 2018 Apr;37(15):2052-2066
Oncogene 2018 Apr;37(15):2052-2066
Quantitative proteomics in Friedreich's ataxia B-lymphocytes: A valuable approach to decipher the biochemical events responsible for pathogenesis.
Télot L, Rousseau E, Lesuisse E, Garcia C, Morlet B, Léger T, Camadro JM, Serre V
Biochimica et biophysica acta. Molecular basis of disease 2018 Apr;1864(4 Pt A):997-1009
Biochimica et biophysica acta. Molecular basis of disease 2018 Apr;1864(4 Pt A):997-1009
Altered redox mitochondrial biology in the neurodegenerative disorder fragile X-tremor/ataxia syndrome: use of antioxidants in precision medicine.
Song G, Napoli E, Wong S, Hagerman R, Liu S, Tassone F, Giulivi C
Molecular medicine (Cambridge, Mass.) 2016 Oct;22:548-559
Molecular medicine (Cambridge, Mass.) 2016 Oct;22:548-559
The Level of ALR is Regulated by the Quantity of Mitochondrial DNA.
Balogh T, Lőrincz T, Stiller I, Mandl J, Bánhegyi G, Szarka A
Pathology oncology research : POR 2016 Apr;22(2):431-7
Pathology oncology research : POR 2016 Apr;22(2):431-7
Loss of apoptosis-inducing factor critically affects MIA40 function.
Meyer K, Buettner S, Ghezzi D, Zeviani M, Bano D, Nicotera P
Cell death & disease 2015 Jul 9;6:e1814
Cell death & disease 2015 Jul 9;6:e1814
MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.
Aras S, Bai M, Lee I, Springett R, Hüttemann M, Grossman LI
Mitochondrion 2015 Jan;20:43-51
Mitochondrion 2015 Jan;20:43-51
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- L02 cells were subjected to SDS PAGE followed by western blot with 21090-1-AP(CHCHD4 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using CHCHD4 antibody 21090-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 21090-1-AP(CHCHD4 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 21090-1-AP(CHCHD4 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
