BS9139

antibody from Bioworld Technology, Inc
Targeting: LAMC3 DKFZp434E202
Provider product page for BS9139
Western blot
Immunohistochemistry

Antibody data

Product number
BS9139 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Laminin ÎÛ 3 (T1385) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 1355-1399 of Human Laminin ÎÛ-3.
Description
Laminins are essential and abundant structural non-collagenous glycoproteins localizing to basement membranes. Basement membranes (cell-associated extracellular matrices (ECMs)) are polymers of laminins with stabilizing type IV collagen networks, nidogen, and several proteoglycans. Basement membranes are found under epithelial layers, around the endothelium of blood vessels, and surrounding muscle, peripheral nerve, and fat cells. Formation of basement membranes influences cell proliferation, phenotype, migration, gene expression, and tissue architecture. Each laminin is a heterotrimer of Ï«, ÉÇ, and ÎÛ chain subunits that undergoes cell-secretion and incorporation into the ECM. Laminins can self-assemble, bind to other matrix macromolecules, and have unique and shared cell interactions mediated by Integrins, dystroglycan, and cognate laminin receptors.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
LAMC3 protein structure - BS9139 shown in red.