Antibody data
- Antibody Data
- Antigen structure
- References [111]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 14295-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14295-1-AP, RRID:AB_1607719
- Product name
- NANOG antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated NANOG antibody (Cat. #14295-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Disturbance in transcriptomic profile, proliferation and multipotency in human mesenchymal stem cells caused by hexafluoropropylene oxides.
Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.
Resveratrol Inhibition of Renal Cancer Stem Cell Characteristics and Modulation of the Sonic Hedgehog Pathway.
Overexpression of P4HA1 associates with poor prognosis and promotes cell proliferation and metastasis of lung adenocarcinoma.
IL20RA signaling enhances stemness and promotes the formation of an immunosuppressive microenvironment in breast cancer.
Long non-coding RNA DUXAP9 promotes hepatocellular carcinoma cell stemness via directly interacting with sox9.
Pharmacological targeting PTK6 inhibits the JAK2/STAT3 sustained stemness and reverses chemoresistance of colorectal cancer.
Gadd45g initiates embryonic stem cell differentiation and inhibits breast cell carcinogenesis.
Circular RNA circIPO11 drives self-renewal of liver cancer initiating cells via Hedgehog signaling.
Inhibition of ubiquitin-specific protease 13-mediated degradation of Raf1 kinase by Spautin-1 has opposing effects in naïve and primed pluripotent stem cells.
Generation of two induced pluripotent stem cell lines from Brugada syndrome affected patients carrying SCN5A mutations.
Generation of three induced pluripotent stem cell lines, SCVIi003-A, SCVIi004-A, SCVIi005-A, from patients with ARVD/C caused by heterozygous mutations in the PKP2 gene.
Generation of two heterozygous MYBPC3 mutation-carrying human iPSC lines, SCVIi001-A and SCVIi002-A, for modeling hypertrophic cardiomyopathy.
CDR1as regulated by hnRNPM maintains stemness of periodontal ligament stem cells via miR-7/KLF4.
ETV4 promotes breast cancer cell stemness by activating glycolysis and CXCR4-mediated sonic Hedgehog signaling.
The whole profiling and competing endogenous RNA network analyses of noncoding RNAs in adipose-derived stem cells from diabetic, old, and young patients.
Apatinib suppresses lung cancer stem-like cells by complex interplay between β-catenin signaling and mitochondrial ROS accumulation.
Diallyl trisulfide inhibited tobacco smoke-mediated bladder EMT and cancer stem cell marker expression via the NF-κB pathway in vivo.
AMD1 upregulates hepatocellular carcinoma cells stemness by FTO mediated mRNA demethylation.
NRF2 is required for structural and metabolic maturation of human induced pluripotent stem cell-derived ardiomyocytes.
Iguratimod-encapsulating PLGA-NPs induce human multiple myeloma cell death via reactive oxygen species and Caspase-dependent signalling.
HET0016 attenuates the stemness of breast cancer cells through targeting CYP4Z1.
SNAT2/SLC38A2 Confers the Stemness of Gastric Cancer Cells via Regulating Glutamine Level.
Prrx1 promotes stemness and angiogenesis via activating TGF-β/smad pathway and upregulating proangiogenic factors in glioma.
The LncRNA RP11-279C4.1 Enhances the Malignant Behaviour of Glioma Cells and Glioma Stem-Like Cells by Regulating the miR-1273g-3p/CBX3 Axis.
Generation of three heterozygous KCNH2 mutation-carrying human induced pluripotent stem cell lines for modeling LQT2 syndrome.
Effect of the interference with DRP1 expression on the biological characteristics of glioma stem cells.
Polychlorinated biphenyl quinone induced the acquisition of cancer stem cells properties and epithelial-mesenchymal transition through Wnt/β-catenin.
Benzidine promotes the stemness of bladder cancer stem cells via activation of the Sonic hedgehog pathway.
Generation of three induced pluripotent stem cell lines from hypertrophic cardiomyopathy patients carrying MYH7 mutations.
5-Azacytidine-Induced Cardiomyocyte Differentiation of Very Small Embryonic-Like Stem Cells.
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
β-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NF-κB Signaling Pathways.
Inhibiting EMT, stemness and cell cycle involved in baicalin-induced growth inhibition and apoptosis in colorectal cancer cells.
The F-box protein FBXO11 restrains hepatocellular carcinoma stemness via promotion of ubiquitin-mediated degradation of Snail.
TAp63α targeting of Lgr5 mediates colorectal cancer stem cell properties and sulforaphane inhibition.
Nanog mediates tobacco smoke-induced enhancement of renal cancer stem cell properties.
Conversion between porcine naïve-like and primed ESCs and specific pluripotency marker identification.
The miRNA-149-5p/MyD88 axis is responsible for ursolic acid-mediated attenuation of the stemness and chemoresistance of non-small cell lung cancer cells.
Bisphenol A and polychlorinated biphenyls enhance the cancer stem cell properties of human ovarian cancer cells by activating the WNT signaling pathway.
lncRNA SLC7A11-AS1 Promotes Chemoresistance by Blocking SCFβ-TRCP-Mediated Degradation of NRF2 in Pancreatic Cancer.
Inhibition of PIM1 attenuates the stem cell-like traits of breast cancer cells by promoting RUNX3 nuclear retention.
Long Non-Coding RNA THOR Enhances the Stem Cell-Like Traits of Triple-Negative Breast Cancer Cells Through Activating β-Catenin Signaling.
Generation of human iPSC line from a patient with Tetralogy of Fallot, YAHKMUi001-A, carrying a mutation in TBX1 gene.
Acylglycerol kinase promotes the stemness of nasopharyngeal carcinoma cells by promoting β-catenin translocation to the nucleus through activating PI3K/Akt pathway.
miR-296-5p suppresses stem cell potency of hepatocellular carcinoma cells via regulating Brg1/Sall4 axis.
Glycochenodeoxycholic acid induces stemness and chemoresistance via the STAT3 signaling pathway in hepatocellular carcinoma cells.
1,25-dihydroxyvitamin D3 signaling-induced decreases in IRX4 inhibits NANOG-mediated cancer stem-like properties and gefitinib resistance in NSCLC cells.
UTX Regulates Human Neural Differentiation and Dendritic Morphology by Resolving Bivalent Promoters.
WIP1 promotes cancer stem cell properties by inhibiting p38 MAPK in NSCLC.
Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis.
COL4A2 in the tissue-specific extracellular matrix plays important role on osteogenic differentiation of periodontal ligament stem cells.
Scorpion Venom Analgesic Peptide, BmK AGAP Inhibits Stemness, and Epithelial-Mesenchymal Transition by Down-Regulating PTX3 in Breast Cancer.
Sonic hedgehog pathway mediates genistein inhibition of renal cancer stem cells.
ROS/KRAS/AMPK Signaling Contributes to Gemcitabine-Induced Stem-like Cell Properties in Pancreatic Cancer.
Long non-coding RNA linc00645 promotes TGF-β-induced epithelial-mesenchymal transition by regulating miR-205-3p-ZEB1 axis in glioma.
Transcription factor Six2 induces a stem cell-like phenotype in renal cell carcinoma cells.
Cinobufotalin powerfully reversed EBV-miR-BART22-induced cisplatin resistance via stimulating MAP2K4 to antagonize non-muscle myosin heavy chain IIA/glycogen synthase 3β/β-catenin signaling pathway.
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
Six1 is negatively correlated with poor prognosis and reduces 5-fluorouracil sensitivity via attenuating the stemness of hepatocellular carcinoma cells.
Pre-metastatic niche triggers SDF-1/CXCR4 axis and promotes organ colonisation by hepatocellular circulating tumour cells via downregulation of Prrx1.
SLC34A2 promotes neuroblastoma cell stemness via enhancement of miR-25/Gsk3β-mediated activation of Wnt/β-catenin signaling.
RNA binding protein PUM2 promotes the stemness of breast cancer cells via competitively binding to neuropilin-1 (NRP-1) mRNA with miR-376a.
TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling.
RNA Targets Ribogenesis Factor WDR43 to Chromatin for Transcription and Pluripotency Control.
Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway.
Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway.
Soft fibrin matrix downregulates DAB2IP to promote Nanog-dependent growth of colon tumor-repopulating cells.
Bruceine D inhibits tumor growth and stem cell-like traits of osteosarcoma through inhibition of STAT3 signaling pathway.
Generation of a homozygous HDAC6 knockout human embryonic stem cell line by CRISPR/Cas9 editing.
Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.
Placental biology of Down syndrome in relation to increased gene dosage.
PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis.
LncRNA THOR increases osteosarcoma cell stemness and migration by enhancing SOX9 mRNA stability.
GTSE1 is involved in breast cancer progression in p53 mutation-dependent manner.
Myeloid-derived suppressor cells endow stem-like qualities to multiple myeloma cells by inducing piRNA-823 expression and DNMT3B activation.
Rapid Differentiation of Multi-Zone Ocular Cells from Human Induced Pluripotent Stem Cells and Generation of Corneal Epithelial and Endothelial Cells.
Carcinoma-associated fibroblasts promote the stemness and chemoresistance of colorectal cancer by transferring exosomal lncRNA H19.
LncRNA UCA1 is necessary for TGF-β-induced epithelial-mesenchymal transition and stemness via acting as a ceRNA for Slug in glioma cells.
Protective effects of α‑2‑macroglobulin on human bone marrow mesenchymal stem cells in radiation injury.
Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway.
Directing Induced Pluripotent Stem Cell Derived Neural Stem Cell Fate with a Three-Dimensional Biomimetic Hydrogel for Spinal Cord Injury Repair.
Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice.
Cigarette smoke stimulates the stemness of renal cancer stem cells via Sonic Hedgehog pathway.
Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells.
Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells.
Effects of baicalein on pancreatic cancer stem cells via modulation of sonic Hedgehog pathway.
Telomeric noncoding RNA promotes mouse embryonic stem cell self-renewal through inhibition of TCF3 activity.
Modulation of STAT3 phosphorylation by PTPN2 inhibits naïve pluripotency of embryonic stem cells.
Leukemia inhibitory factor regulates marmoset induced pluripotent stem cell proliferation via a PI3K/Akt‑dependent Tbx‑3 activation pathway.
Wnt/β-catenin modulates chronic tobacco smoke exposure-induced acquisition of pulmonary cancer stem cell properties and diallyl trisulfide intervention.
Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness.
Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.
MeCP2 deficiency promotes cell reprogramming by stimulating IGF1/AKT/mTOR signaling and activating ribosomal protein-mediated cell cycle gene translation.
Disulfiram/copper targets stem cell-like ALDH+ population of multiple myeloma by inhibition of ALDH1A1 and Hedgehog pathway.
Six2 is negatively correlated with good prognosis and decreases 5-FU sensitivity via suppressing E-cadherin expression in hepatocellular carcinoma cells.
Bufalin reverses acquired drug resistance by inhibiting stemness in colorectal cancer cells.
Knockdown of SALL4 expression using RNA interference induces cell cycle arrest, enhances early apoptosis, inhibits invasion and increases chemosensitivity to temozolomide in U251 glioma cells.
The transcription factor Gbx2 induces expression of Kruppel-like factor 4 to maintain and induce naïve pluripotency of embryonic stem cells.
Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway.
miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells.
Generation and characterization of induced pluripotent stem cells from guinea pig fetal fibroblasts.
(-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway.
Linc-DYNC2H1-4 promotes EMT and CSC phenotypes by acting as a sponge of miR-145 in pancreatic cancer cells.
Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells.
Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.
Small-Activating RNA Can Change Nucleosome Positioning in Human Fibroblasts.
The endoplasmic reticulum-mitochondria interface is perturbed in PARK2 knockout mice and patients with PARK2 mutations.
ROCK inhibitor Y27632 promotes proliferation and diminishes apoptosis of marmoset induced pluripotent stem cells by suppressing expression and activity of caspase 3.
MicroRNA-490-3P targets CDK1 and inhibits ovarian epithelial carcinoma tumorigenesis and progression.
Loss of SNAIL regulated miR-128-2 on chromosome 3p22.3 targets multiple stem cell factors to promote transformation of mammary epithelial cells.
Pan Y, Qin H, Zheng L, Guo Y, Liu W
Environmental pollution (Barking, Essex : 1987) 2022 Jan 1;292(Pt B):118483
Environmental pollution (Barking, Essex : 1987) 2022 Jan 1;292(Pt B):118483
Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.
Cao W, Li Y, Sun H, Yang C, Zhu J, Xie C, Li X, Wu J, Geng S, Wang L, Sun L, Geng G, Han H, Zhong C
Frontiers in cell and developmental biology 2021;9:679806
Frontiers in cell and developmental biology 2021;9:679806
Resveratrol Inhibition of Renal Cancer Stem Cell Characteristics and Modulation of the Sonic Hedgehog Pathway.
Sun H, Zhang T, Liu R, Cao W, Zhang Z, Liu Z, Qian W, Wang D, Yu D, Zhong C
Nutrition and cancer 2021;73(7):1157-1167
Nutrition and cancer 2021;73(7):1157-1167
Overexpression of P4HA1 associates with poor prognosis and promotes cell proliferation and metastasis of lung adenocarcinoma.
Ning Y, Zheng H, Zhan Y, Liu S, Yang Y, Zang H, Wen Q, Zhang Y, Fan S
Journal of Cancer 2021;12(22):6685-6694
Journal of Cancer 2021;12(22):6685-6694
IL20RA signaling enhances stemness and promotes the formation of an immunosuppressive microenvironment in breast cancer.
Gao W, Wen H, Liang L, Dong X, Du R, Zhou W, Zhang X, Zhang C, Xiang R, Li N
Theranostics 2021;11(6):2564-2580
Theranostics 2021;11(6):2564-2580
Long non-coding RNA DUXAP9 promotes hepatocellular carcinoma cell stemness via directly interacting with sox9.
Zeng R, Wang C, Wang W, Wang S
Environmental toxicology 2021 Sep;36(9):1793-1801
Environmental toxicology 2021 Sep;36(9):1793-1801
Pharmacological targeting PTK6 inhibits the JAK2/STAT3 sustained stemness and reverses chemoresistance of colorectal cancer.
Liu C, Pan Z, Chen Q, Chen Z, Liu W, Wu L, Jiang M, Lin W, Zhang Y, Lin W, Zhou R, Zhao L
Journal of experimental & clinical cancer research : CR 2021 Sep 22;40(1):297
Journal of experimental & clinical cancer research : CR 2021 Sep 22;40(1):297
Gadd45g initiates embryonic stem cell differentiation and inhibits breast cell carcinogenesis.
Zhang X, Li Y, Ji J, Wang X, Zhang M, Li X, Zhang Y, Zhu Z, Ye SD, Wang X
Cell death discovery 2021 Oct 2;7(1):271
Cell death discovery 2021 Oct 2;7(1):271
Circular RNA circIPO11 drives self-renewal of liver cancer initiating cells via Hedgehog signaling.
Gu Y, Wang Y, He L, Zhang J, Zhu X, Liu N, Wang J, Lu T, He L, Tian Y, Fan Z
Molecular cancer 2021 Oct 14;20(1):132
Molecular cancer 2021 Oct 14;20(1):132
Inhibition of ubiquitin-specific protease 13-mediated degradation of Raf1 kinase by Spautin-1 has opposing effects in naïve and primed pluripotent stem cells.
Wang X, Wang X, Zhang X, Zhang Y, Zhu Z, Li Y, Zhang M, Ji J, Yu Y, Ye SD
The Journal of biological chemistry 2021 Nov;297(5):101332
The Journal of biological chemistry 2021 Nov;297(5):101332
Generation of two induced pluripotent stem cell lines from Brugada syndrome affected patients carrying SCN5A mutations.
Belbachir N, Lai C, Rhee JW, Zhuge Y, Perez MV, Sallam K, Wu JC
Stem cell research 2021 Nov 23;57:102605
Stem cell research 2021 Nov 23;57:102605
Generation of three induced pluripotent stem cell lines, SCVIi003-A, SCVIi004-A, SCVIi005-A, from patients with ARVD/C caused by heterozygous mutations in the PKP2 gene.
Jahng JWS, Black KE, Liu L, Bae HR, Perez M, Ashley EA, Sallam K, Wu JC
Stem cell research 2021 May;53:102284
Stem cell research 2021 May;53:102284
Generation of two heterozygous MYBPC3 mutation-carrying human iPSC lines, SCVIi001-A and SCVIi002-A, for modeling hypertrophic cardiomyopathy.
Liu L, Shenoy SP, Jahng JWS, Liu Y, Knowles JW, Zhuge Y, Wu JC
Stem cell research 2021 May;53:102279
Stem cell research 2021 May;53:102279
CDR1as regulated by hnRNPM maintains stemness of periodontal ligament stem cells via miR-7/KLF4.
Gu X, Li X, Jin Y, Zhang Z, Li M, Liu D, Wei F
Journal of cellular and molecular medicine 2021 May;25(9):4501-4515
Journal of cellular and molecular medicine 2021 May;25(9):4501-4515
ETV4 promotes breast cancer cell stemness by activating glycolysis and CXCR4-mediated sonic Hedgehog signaling.
Zhu T, Zheng J, Zhuo W, Pan P, Li M, Zhang W, Zhou H, Gao Y, Li X, Liu Z
Cell death discovery 2021 May 29;7(1):126
Cell death discovery 2021 May 29;7(1):126
The whole profiling and competing endogenous RNA network analyses of noncoding RNAs in adipose-derived stem cells from diabetic, old, and young patients.
Ren S, Xiong H, Chen J, Yang X, Liu Y, Guo J, Jiang T, Xu Z, Yuan M, Liu Y, Zhou N, Chen H, Li W, Machens HG, Chen Z
Stem cell research & therapy 2021 May 29;12(1):313
Stem cell research & therapy 2021 May 29;12(1):313
Apatinib suppresses lung cancer stem-like cells by complex interplay between β-catenin signaling and mitochondrial ROS accumulation.
Zhu J, Li X, Liang C, Zhou X, Ge M, Chen Y, Jin J, Yin J, Xu H, Xie C, Zhong C
Cell death discovery 2021 May 12;7(1):102
Cell death discovery 2021 May 12;7(1):102
Diallyl trisulfide inhibited tobacco smoke-mediated bladder EMT and cancer stem cell marker expression via the NF-κB pathway in vivo.
Geng H, Guo W, Feng L, Xie D, Bi L, Wang Y, Zhang T, Liang Z, Yu D
The Journal of international medical research 2021 Mar;49(3):300060521992900
The Journal of international medical research 2021 Mar;49(3):300060521992900
AMD1 upregulates hepatocellular carcinoma cells stemness by FTO mediated mRNA demethylation.
Bian X, Shi D, Xing K, Zhou H, Lu L, Yu D, Wu W
Clinical and translational medicine 2021 Mar;11(3):e352
Clinical and translational medicine 2021 Mar;11(3):e352
NRF2 is required for structural and metabolic maturation of human induced pluripotent stem cell-derived ardiomyocytes.
Zhang X, Ye L, Xu H, Zhou Q, Tan B, Yi Q, Yan L, Xie M, Zhang Y, Tian J, Zhu J
Stem cell research & therapy 2021 Mar 24;12(1):208
Stem cell research & therapy 2021 Mar 24;12(1):208
Iguratimod-encapsulating PLGA-NPs induce human multiple myeloma cell death via reactive oxygen species and Caspase-dependent signalling.
Wang F, Younis M, Luo Y, Zhang L, Yuan L
International immunopharmacology 2021 Jun;95:107532
International immunopharmacology 2021 Jun;95:107532
HET0016 attenuates the stemness of breast cancer cells through targeting CYP4Z1.
Liu H, Qin H, Zhou Y, Yuan Y, Liu Y, Chen Y, Yang Y, Ni H, Xi T, Zheng L
Molecular carcinogenesis 2021 Jun;60(6):413-426
Molecular carcinogenesis 2021 Jun;60(6):413-426
SNAT2/SLC38A2 Confers the Stemness of Gastric Cancer Cells via Regulating Glutamine Level.
Nie K, Cai M
Digestive diseases and sciences 2021 Jun 25;
Digestive diseases and sciences 2021 Jun 25;
Prrx1 promotes stemness and angiogenesis via activating TGF-β/smad pathway and upregulating proangiogenic factors in glioma.
Chen Z, Chen Y, Li Y, Lian W, Zheng K, Zhang Y, Zhang Y, Lin C, Liu C, Sun F, Sun X, Wang J, Zhao L, Ke Y
Cell death & disease 2021 Jun 15;12(6):615
Cell death & disease 2021 Jun 15;12(6):615
The LncRNA RP11-279C4.1 Enhances the Malignant Behaviour of Glioma Cells and Glioma Stem-Like Cells by Regulating the miR-1273g-3p/CBX3 Axis.
Wang F, Zhang L, Luo Y, Zhang Q, Zhang Y, Shao Y, Yuan L
Molecular neurobiology 2021 Jul;58(7):3362-3373
Molecular neurobiology 2021 Jul;58(7):3362-3373
Generation of three heterozygous KCNH2 mutation-carrying human induced pluripotent stem cell lines for modeling LQT2 syndrome.
Mondéjar-Parreño G, Jahng JWS, Belbachir N, Wu BC, Zhang X, Perez MV, Badhwar N, Wu JC
Stem cell research 2021 Jul;54:102402
Stem cell research 2021 Jul;54:102402
Effect of the interference with DRP1 expression on the biological characteristics of glioma stem cells.
Zhang L, Cao H, Tao H, Yang J, Gong W, Hu Q
Experimental and therapeutic medicine 2021 Jul;22(1):696
Experimental and therapeutic medicine 2021 Jul;22(1):696
Polychlorinated biphenyl quinone induced the acquisition of cancer stem cells properties and epithelial-mesenchymal transition through Wnt/β-catenin.
Qin Q, Yang B, Liu Z, Xu L, Song E, Song Y
Chemosphere 2021 Jan;263:128125
Chemosphere 2021 Jan;263:128125
Benzidine promotes the stemness of bladder cancer stem cells via activation of the Sonic hedgehog pathway.
Wang D, Xie D, Bi L, Wang Y, Zou C, Chen L, Geng H, Qian W, Li Y, Sun H, Wang X, Lu Y, Yu D, Zhong C
Oncology letters 2021 Feb;21(2):146
Oncology letters 2021 Feb;21(2):146
Generation of three induced pluripotent stem cell lines from hypertrophic cardiomyopathy patients carrying MYH7 mutations.
Cao X, Jahng JWS, Lee C, Zha Y, Wheeler MT, Sallam K, Wu JC
Stem cell research 2021 Aug;55:102455
Stem cell research 2021 Aug;55:102455
5-Azacytidine-Induced Cardiomyocyte Differentiation of Very Small Embryonic-Like Stem Cells.
Sun X, Li H, Zhu Y, Xu P, Zuo Q, Li B, Gu X
Stem cells international 2020;2020:5162350
Stem cells international 2020;2020:5162350
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
Sun X, Song J, Li E, Geng H, Li Y, Yu D, Zhong C
International journal of clinical and experimental pathology 2020;13(6):1333-1348
International journal of clinical and experimental pathology 2020;13(6):1333-1348
β-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NF-κB Signaling Pathways.
Su P, Ahmad B, Zou K, Zou L
OncoTargets and therapy 2020;13:5207-5222
OncoTargets and therapy 2020;13:5207-5222
Inhibiting EMT, stemness and cell cycle involved in baicalin-induced growth inhibition and apoptosis in colorectal cancer cells.
Yang B, Bai H, Sa Y, Zhu P, Liu P
Journal of Cancer 2020;11(8):2303-2317
Journal of Cancer 2020;11(8):2303-2317
The F-box protein FBXO11 restrains hepatocellular carcinoma stemness via promotion of ubiquitin-mediated degradation of Snail.
Shao L, Zhang X, Yao Q
FEBS open bio 2020 Sep;10(9):1810-1820
FEBS open bio 2020 Sep;10(9):1810-1820
TAp63α targeting of Lgr5 mediates colorectal cancer stem cell properties and sulforaphane inhibition.
Chen Y, Wang MH, Zhu JY, Xie CF, Li XT, Wu JS, Geng SS, Han HY, Zhong CY
Oncogenesis 2020 Oct 10;9(10):89
Oncogenesis 2020 Oct 10;9(10):89
Nanog mediates tobacco smoke-induced enhancement of renal cancer stem cell properties.
Zhang T, Sun H, Liu R, Cao W, Zhang T, Li E, Sun X, Wu W, Yu D, Zhong C
Environmental toxicology 2020 Nov;35(11):1274-1283
Environmental toxicology 2020 Nov;35(11):1274-1283
Conversion between porcine naïve-like and primed ESCs and specific pluripotency marker identification.
Chen Q, Zhang H, Jiang H, Zhang M, Wang J, Zhao L, Wang C, Liu M, Li R
In vitro cellular & developmental biology. Animal 2020 May;56(5):412-423
In vitro cellular & developmental biology. Animal 2020 May;56(5):412-423
The miRNA-149-5p/MyD88 axis is responsible for ursolic acid-mediated attenuation of the stemness and chemoresistance of non-small cell lung cancer cells.
Chen Q, Luo J, Wu C, Lu H, Cai S, Bao C, Liu D, Kong J
Environmental toxicology 2020 May;35(5):561-569
Environmental toxicology 2020 May;35(5):561-569
Bisphenol A and polychlorinated biphenyls enhance the cancer stem cell properties of human ovarian cancer cells by activating the WNT signaling pathway.
Guo Y, Li B, Yan X, Shen X, Ma J, Liu S, Zhang D
Chemosphere 2020 May;246:125775
Chemosphere 2020 May;246:125775
lncRNA SLC7A11-AS1 Promotes Chemoresistance by Blocking SCFβ-TRCP-Mediated Degradation of NRF2 in Pancreatic Cancer.
Yang Q, Li K, Huang X, Zhao C, Mei Y, Li X, Jiao L, Yang H
Molecular therapy. Nucleic acids 2020 Mar 6;19:974-985
Molecular therapy. Nucleic acids 2020 Mar 6;19:974-985
Inhibition of PIM1 attenuates the stem cell-like traits of breast cancer cells by promoting RUNX3 nuclear retention.
Liu H, Chen C, Ma D, Li Y, Yin Q, Li Q, Xiang C
Journal of cellular and molecular medicine 2020 Jun;24(11):6308-6323
Journal of cellular and molecular medicine 2020 Jun;24(11):6308-6323
Long Non-Coding RNA THOR Enhances the Stem Cell-Like Traits of Triple-Negative Breast Cancer Cells Through Activating β-Catenin Signaling.
Wang B, Ye Q, Zou C
Medical science monitor : international medical journal of experimental and clinical research 2020 Jul 14;26:e923507
Medical science monitor : international medical journal of experimental and clinical research 2020 Jul 14;26:e923507
Generation of human iPSC line from a patient with Tetralogy of Fallot, YAHKMUi001-A, carrying a mutation in TBX1 gene.
Han S, Zhang YY, Meng MY, Hou ZL, Meng P, Zhao YY, Gao H, Tang J, Liu Z, Yang LL, Jiang LH, Li YX
Stem cell research 2020 Jan;42:101687
Stem cell research 2020 Jan;42:101687
Acylglycerol kinase promotes the stemness of nasopharyngeal carcinoma cells by promoting β-catenin translocation to the nucleus through activating PI3K/Akt pathway.
Zhao Q, Sun P, Qin S, Liu J
Environmental toxicology 2020 Dec;35(12):1299-1307
Environmental toxicology 2020 Dec;35(12):1299-1307
miR-296-5p suppresses stem cell potency of hepatocellular carcinoma cells via regulating Brg1/Sall4 axis.
Shi DM, Shi XL, Xing KL, Zhou HX, Lu LL, Wu WZ
Cellular signalling 2020 Aug;72:109650
Cellular signalling 2020 Aug;72:109650
Glycochenodeoxycholic acid induces stemness and chemoresistance via the STAT3 signaling pathway in hepatocellular carcinoma cells.
Shi C, Yang J, Hu L, Liao B, Qiao L, Shen W, Xie F, Zhu G
Aging 2020 Aug 3;12(15):15546-15555
Aging 2020 Aug 3;12(15):15546-15555
1,25-dihydroxyvitamin D3 signaling-induced decreases in IRX4 inhibits NANOG-mediated cancer stem-like properties and gefitinib resistance in NSCLC cells.
Jia Z, Zhang Y, Yan A, Wang M, Han Q, Wang K, Wang J, Qiao C, Pan Z, Chen C, Hu D, Ding X
Cell death & disease 2020 Aug 20;11(8):670
Cell death & disease 2020 Aug 20;11(8):670
UTX Regulates Human Neural Differentiation and Dendritic Morphology by Resolving Bivalent Promoters.
Tang QY, Zhang SF, Dai SK, Liu C, Wang YY, Du HZ, Teng ZQ, Liu CM
Stem cell reports 2020 Aug 11;15(2):439-453
Stem cell reports 2020 Aug 11;15(2):439-453
WIP1 promotes cancer stem cell properties by inhibiting p38 MAPK in NSCLC.
Deng K, Liu L, Tan X, Zhang Z, Li J, Ou Y, Wang X, Yang S, Xiang R, Sun P
Signal transduction and targeted therapy 2020 Apr 15;5(1):36
Signal transduction and targeted therapy 2020 Apr 15;5(1):36
Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis.
Xie C, Zhu J, Jiang Y, Chen J, Wang X, Geng S, Wu J, Zhong C, Li X, Meng Z
Theranostics 2019;9(16):4827-4840
Theranostics 2019;9(16):4827-4840
COL4A2 in the tissue-specific extracellular matrix plays important role on osteogenic differentiation of periodontal ligament stem cells.
Wen Y, Yang H, Wu J, Wang A, Chen X, Hu S, Zhang Y, Bai D, Jin Z
Theranostics 2019;9(15):4265-4286
Theranostics 2019;9(15):4265-4286
Scorpion Venom Analgesic Peptide, BmK AGAP Inhibits Stemness, and Epithelial-Mesenchymal Transition by Down-Regulating PTX3 in Breast Cancer.
Kampo S, Ahmmed B, Zhou T, Owusu L, Anabah TW, Doudou NR, Kuugbee ED, Cui Y, Lu Z, Yan Q, Wen QP
Frontiers in oncology 2019;9:21
Frontiers in oncology 2019;9:21
Sonic hedgehog pathway mediates genistein inhibition of renal cancer stem cells.
Li E, Zhang T, Sun X, Li Y, Geng H, Yu D, Zhong C
Oncology letters 2019 Sep;18(3):3081-3091
Oncology letters 2019 Sep;18(3):3081-3091
ROS/KRAS/AMPK Signaling Contributes to Gemcitabine-Induced Stem-like Cell Properties in Pancreatic Cancer.
Zhao H, Wu S, Li H, Duan Q, Zhang Z, Shen Q, Wang C, Yin T
Molecular therapy oncolytics 2019 Sep 27;14:299-312
Molecular therapy oncolytics 2019 Sep 27;14:299-312
Long non-coding RNA linc00645 promotes TGF-β-induced epithelial-mesenchymal transition by regulating miR-205-3p-ZEB1 axis in glioma.
Li C, Zheng H, Hou W, Bao H, Xiong J, Che W, Gu Y, Sun H, Liang P
Cell death & disease 2019 Sep 26;10(10):717
Cell death & disease 2019 Sep 26;10(10):717
Transcription factor Six2 induces a stem cell-like phenotype in renal cell carcinoma cells.
Cheng N, Li H, Han Y, Sun S
FEBS open bio 2019 Oct;9(10):1808-1816
FEBS open bio 2019 Oct;9(10):1808-1816
Cinobufotalin powerfully reversed EBV-miR-BART22-induced cisplatin resistance via stimulating MAP2K4 to antagonize non-muscle myosin heavy chain IIA/glycogen synthase 3β/β-catenin signaling pathway.
Liu Y, Jiang Q, Liu X, Lin X, Tang Z, Liu C, Zhou J, Zhao M, Li X, Cheng Z, Li L, Xie Y, Liu Z, Fang W
EBioMedicine 2019 Oct;48:386-404
EBioMedicine 2019 Oct;48:386-404
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
Zhang Q, Cao WS, Wang XQ, Zhang M, Lu XM, Chen JQ, Chen Y, Ge MM, Zhong CY, Han HY
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791
Six1 is negatively correlated with poor prognosis and reduces 5-fluorouracil sensitivity via attenuating the stemness of hepatocellular carcinoma cells.
Chen K, Wei H, Pan J, Chen Z, Pan D, Gao T, Huang J, Huang M, Ou M, Zhong W
European journal of pharmacology 2019 Oct 15;861:172599
European journal of pharmacology 2019 Oct 15;861:172599
Pre-metastatic niche triggers SDF-1/CXCR4 axis and promotes organ colonisation by hepatocellular circulating tumour cells via downregulation of Prrx1.
Tang Y, Lu Y, Chen Y, Luo L, Cai L, Peng B, Huang W, Liao H, Zhao L, Pan M
Journal of experimental & clinical cancer research : CR 2019 Nov 21;38(1):473
Journal of experimental & clinical cancer research : CR 2019 Nov 21;38(1):473
SLC34A2 promotes neuroblastoma cell stemness via enhancement of miR-25/Gsk3β-mediated activation of Wnt/β-catenin signaling.
Chen J, Wang P, Cai R, Peng H, Zhang C, Zhang M
FEBS open bio 2019 Mar;9(3):527-537
FEBS open bio 2019 Mar;9(3):527-537
RNA binding protein PUM2 promotes the stemness of breast cancer cells via competitively binding to neuropilin-1 (NRP-1) mRNA with miR-376a.
Zhang L, Chen Y, Li C, Liu J, Ren H, Li L, Zheng X, Wang H, Han Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jun;114:108772
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jun;114:108772
TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling.
Zhu R, Gires O, Zhu L, Liu J, Li J, Yang H, Ju G, Huang J, Ge W, Chen Y, Lu Z, Wang H
Nature communications 2019 Jun 28;10(1):2863
Nature communications 2019 Jun 28;10(1):2863
RNA Targets Ribogenesis Factor WDR43 to Chromatin for Transcription and Pluripotency Control.
Bi X, Xu Y, Li T, Li X, Li W, Shao W, Wang K, Zhan G, Wu Z, Liu W, Lu JY, Wang L, Zhao J, Wu J, Na J, Li G, Li P, Shen X
Molecular cell 2019 Jul 11;75(1):102-116.e9
Molecular cell 2019 Jul 11;75(1):102-116.e9
Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway.
Li B, Cao Y, Meng G, Qian L, Xu T, Yan C, Luo O, Wang S, Wei J, Ding Y, Yu D
EBioMedicine 2019 Jan;39:239-254
EBioMedicine 2019 Jan;39:239-254
Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway.
Xie C, Zhu J, Wang X, Chen J, Geng S, Wu J, Zhong C, Li X
Journal of experimental & clinical cancer research : CR 2019 Jan 28;38(1):39
Journal of experimental & clinical cancer research : CR 2019 Jan 28;38(1):39
Soft fibrin matrix downregulates DAB2IP to promote Nanog-dependent growth of colon tumor-repopulating cells.
Zhang M, Xu C, Wang HZ, Peng YN, Li HO, Zhou YJ, Liu S, Wang F, Liu L, Chang Y, Zhao Q, Liu J
Cell death & disease 2019 Feb 15;10(3):151
Cell death & disease 2019 Feb 15;10(3):151
Bruceine D inhibits tumor growth and stem cell-like traits of osteosarcoma through inhibition of STAT3 signaling pathway.
Wang S, Hu H, Zhong B, Shi D, Qing X, Cheng C, Deng X, Zhang Z, Shao Z
Cancer medicine 2019 Dec;8(17):7345-7358
Cancer medicine 2019 Dec;8(17):7345-7358
Generation of a homozygous HDAC6 knockout human embryonic stem cell line by CRISPR/Cas9 editing.
Xie L, Huang J, Li X, Dai L, Lin X, Zhang J, Luo J, Zhang W
Stem cell research 2019 Dec;41:101610
Stem cell research 2019 Dec;41:101610
Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.
Ge M, Zhang L, Cao L, Xie C, Li X, Li Y, Meng Y, Chen Y, Wang X, Chen J, Zhang Q, Shao J, Zhong C
International journal of food sciences and nutrition 2019 Aug;70(5):570-578
International journal of food sciences and nutrition 2019 Aug;70(5):570-578
Placental biology of Down syndrome in relation to increased gene dosage.
Wong OGW, Ngan HYS, Cheung ANY
Hong Kong medical journal = Xianggang yi xue za zhi 2019 Aug;25 Suppl 5(4):33-35
Hong Kong medical journal = Xianggang yi xue za zhi 2019 Aug;25 Suppl 5(4):33-35
PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis.
Jiang Y, Liu F, Zou F, Zhang Y, Wang B, Zhang Y, Lian A, Han X, Liu Z, Liu X, Jin M, Wang D, Li G, Liu J
Stem cell research & therapy 2019 Aug 23;10(1):268
Stem cell research & therapy 2019 Aug 23;10(1):268
LncRNA THOR increases osteosarcoma cell stemness and migration by enhancing SOX9 mRNA stability.
Wu H, He Y, Chen H, Liu Y, Wei B, Chen G, Lin H, Lin H
FEBS open bio 2019 Apr;9(4):781-790
FEBS open bio 2019 Apr;9(4):781-790
GTSE1 is involved in breast cancer progression in p53 mutation-dependent manner.
Lin F, Xie YJ, Zhang XK, Huang TJ, Xu HF, Mei Y, Liang H, Hu H, Lin ST, Luo FF, Lang YH, Peng LX, Qian CN, Huang BJ
Journal of experimental & clinical cancer research : CR 2019 Apr 8;38(1):152
Journal of experimental & clinical cancer research : CR 2019 Apr 8;38(1):152
Myeloid-derived suppressor cells endow stem-like qualities to multiple myeloma cells by inducing piRNA-823 expression and DNMT3B activation.
Ai L, Mu S, Sun C, Fan F, Yan H, Qin Y, Cui G, Wang Y, Guo T, Mei H, Wang H, Hu Y
Molecular cancer 2019 Apr 13;18(1):88
Molecular cancer 2019 Apr 13;18(1):88
Rapid Differentiation of Multi-Zone Ocular Cells from Human Induced Pluripotent Stem Cells and Generation of Corneal Epithelial and Endothelial Cells.
Li Z, Duan H, Li W, Hu X, Jia Y, Zhao C, Zhang S, Zhou Q, Shi W
Stem cells and development 2019 Apr 1;28(7):454-463
Stem cells and development 2019 Apr 1;28(7):454-463
Carcinoma-associated fibroblasts promote the stemness and chemoresistance of colorectal cancer by transferring exosomal lncRNA H19.
Ren J, Ding L, Zhang D, Shi G, Xu Q, Shen S, Wang Y, Wang T, Hou Y
Theranostics 2018;8(14):3932-3948
Theranostics 2018;8(14):3932-3948
LncRNA UCA1 is necessary for TGF-β-induced epithelial-mesenchymal transition and stemness via acting as a ceRNA for Slug in glioma cells.
Li Z, Liu H, Zhong Q, Wu J, Tang Z
FEBS open bio 2018 Nov;8(11):1855-1865
FEBS open bio 2018 Nov;8(11):1855-1865
Protective effects of α‑2‑macroglobulin on human bone marrow mesenchymal stem cells in radiation injury.
Liu Y, Cao W, Kong X, Li J, Chen X, Ge Y, Zhong W, Fang S
Molecular medicine reports 2018 Nov;18(5):4219-4228
Molecular medicine reports 2018 Nov;18(5):4219-4228
Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway.
Li X, Meng Y, Xie C, Zhu J, Wang X, Li Y, Geng S, Wu J, Zhong C, Li M
Journal of cellular biochemistry 2018 May;119(5):4134-4141
Journal of cellular biochemistry 2018 May;119(5):4134-4141
Directing Induced Pluripotent Stem Cell Derived Neural Stem Cell Fate with a Three-Dimensional Biomimetic Hydrogel for Spinal Cord Injury Repair.
Fan L, Liu C, Chen X, Zou Y, Zhou Z, Lin C, Tan G, Zhou L, Ning C, Wang Q
ACS applied materials & interfaces 2018 May 30;10(21):17742-17755
ACS applied materials & interfaces 2018 May 30;10(21):17742-17755
Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice.
Ye B, Liu B, Hao L, Zhu X, Yang L, Wang S, Xia P, Du Y, Meng S, Huang G, Qin X, Wang Y, Yan X, Li C, Hao J, Zhu P, He L, Tian Y, Fan Z
Nature communications 2018 Mar 28;9(1):1261
Nature communications 2018 Mar 28;9(1):1261
Cigarette smoke stimulates the stemness of renal cancer stem cells via Sonic Hedgehog pathway.
Qian W, Kong X, Zhang T, Wang D, Song J, Li Y, Li X, Geng H, Min J, Kong Q, Liu J, Liu Z, Wang D, Zhang Z, Yu D, Zhong C
Oncogenesis 2018 Mar 13;7(3):24
Oncogenesis 2018 Mar 13;7(3):24
Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells.
Zhang Q, Li XT, Chen Y, Chen JQ, Zhu JY, Meng Y, Wang XQ, Li Y, Geng SS, Xie CF, Wu JS, Zhong CY, Han HY
Cancer chemotherapy and pharmacology 2018 Jun;81(6):969-977
Cancer chemotherapy and pharmacology 2018 Jun;81(6):969-977
Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells.
Jia W, Jiang X, Liu W, Wang L, Zhu B, Zhu H, Liu X, Zhong M, Xie D, Huang W, Jia W, Li S, Liu X, Zuo X, Cheng D, Dai J, Ren C
International journal of oncology 2018 Jun;52(6):1787-1800
International journal of oncology 2018 Jun;52(6):1787-1800
Effects of baicalein on pancreatic cancer stem cells via modulation of sonic Hedgehog pathway.
Song L, Chen X, Wang P, Gao S, Qu C, Liu L
Acta biochimica et biophysica Sinica 2018 Jun 1;50(6):586-596
Acta biochimica et biophysica Sinica 2018 Jun 1;50(6):586-596
Telomeric noncoding RNA promotes mouse embryonic stem cell self-renewal through inhibition of TCF3 activity.
Xu X, Guo M, Zhang N, Ye S
American journal of physiology. Cell physiology 2018 Jun 1;314(6):C712-C720
American journal of physiology. Cell physiology 2018 Jun 1;314(6):C712-C720
Modulation of STAT3 phosphorylation by PTPN2 inhibits naïve pluripotency of embryonic stem cells.
Zhang Y, Ding H, Wang X, Ye SD
FEBS letters 2018 Jul;592(13):2227-2237
FEBS letters 2018 Jul;592(13):2227-2237
Leukemia inhibitory factor regulates marmoset induced pluripotent stem cell proliferation via a PI3K/Akt‑dependent Tbx‑3 activation pathway.
Ke M, He Q, Hong D, Li O, Zhu M, Ou WB, He Y, Wu Y
International journal of molecular medicine 2018 Jul;42(1):131-140
International journal of molecular medicine 2018 Jul;42(1):131-140
Wnt/β-catenin modulates chronic tobacco smoke exposure-induced acquisition of pulmonary cancer stem cell properties and diallyl trisulfide intervention.
Wang J, Chen J, Jiang Y, Shi Y, Zhu J, Xie C, Geng S, Wu J, Zhang Q, Wang X, Meng Y, Li Y, Chen Y, Cao W, Wang X, Zhong C, Li X
Toxicology letters 2018 Jul;291:70-76
Toxicology letters 2018 Jul;291:70-76
Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness.
Wang J, Tian L, Khan MN, Zhang L, Chen Q, Zhao Y, Yan Q, Fu L, Liu J
Cancer letters 2018 Feb 28;415:73-85
Cancer letters 2018 Feb 28;415:73-85
Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.
Chen Y, Li Y, Wang XQ, Meng Y, Zhang Q, Zhu JY, Chen JQ, Cao WS, Wang XQ, Xie CF, Li XT, Geng SS, Wu JS, Zhong CY, Han HY
Phytotherapy research : PTR 2018 Dec;32(12):2447-2455
Phytotherapy research : PTR 2018 Dec;32(12):2447-2455
MeCP2 deficiency promotes cell reprogramming by stimulating IGF1/AKT/mTOR signaling and activating ribosomal protein-mediated cell cycle gene translation.
Zhang W, Feng G, Wang L, Teng F, Wang L, Li W, Zhang Y, Zhou Q
Journal of molecular cell biology 2018 Dec 1;10(6):515-526
Journal of molecular cell biology 2018 Dec 1;10(6):515-526
Disulfiram/copper targets stem cell-like ALDH+ population of multiple myeloma by inhibition of ALDH1A1 and Hedgehog pathway.
Jin N, Zhu X, Cheng F, Zhang L
Journal of cellular biochemistry 2018 Aug;119(8):6882-6893
Journal of cellular biochemistry 2018 Aug;119(8):6882-6893
Six2 is negatively correlated with good prognosis and decreases 5-FU sensitivity via suppressing E-cadherin expression in hepatocellular carcinoma cells.
Li JW, Huang CZ, Li JH, Yuan JH, Chen QH, Zhang WF, Xu ZS, Liu YP, Li Y, Zhan MX, Lu LG
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:204-210
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:204-210
Bufalin reverses acquired drug resistance by inhibiting stemness in colorectal cancer cells.
Sun J, Xu K, Qiu Y, Gao H, Xu J, Tang Q, Yin P
Oncology reports 2017 Sep;38(3):1420-1430
Oncology reports 2017 Sep;38(3):1420-1430
Knockdown of SALL4 expression using RNA interference induces cell cycle arrest, enhances early apoptosis, inhibits invasion and increases chemosensitivity to temozolomide in U251 glioma cells.
Zhang L, Yan Y, Jiang Y, Qian J, Jiang L, Hu G, Lu Y, Luo C
Oncology letters 2017 Oct;14(4):4263-4269
Oncology letters 2017 Oct;14(4):4263-4269
The transcription factor Gbx2 induces expression of Kruppel-like factor 4 to maintain and induce naïve pluripotency of embryonic stem cells.
Wang M, Tang L, Liu D, Ying QL, Ye S
The Journal of biological chemistry 2017 Oct 13;292(41):17121-17128
The Journal of biological chemistry 2017 Oct 13;292(41):17121-17128
Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway.
Wang D, Kong X, Li Y, Qian W, Ma J, Wang D, Yu D, Zhong C
Biochemical and biophysical research communications 2017 Nov 4;493(1):521-527
Biochemical and biophysical research communications 2017 Nov 4;493(1):521-527
miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells.
Zhu J, Wang S, Chen Y, Li X, Jiang Y, Yang X, Li Y, Wang X, Meng Y, Zhu M, Ma X, Huang C, Wu R, Xie C, Geng S, Wu J, Zhong C, Han H
The Journal of nutritional biochemistry 2017 Jun;44:80-91
The Journal of nutritional biochemistry 2017 Jun;44:80-91
Generation and characterization of induced pluripotent stem cells from guinea pig fetal fibroblasts.
Wu Y, Li O, He C, Li Y, Li M, Liu XL, Wang Y, He Y
Molecular medicine reports 2017 Jun;15(6):3690-3698
Molecular medicine reports 2017 Jun;15(6):3690-3698
(-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway.
Chen Y, Wang XQ, Zhang Q, Zhu JY, Li Y, Xie CF, Li XT, Wu JS, Geng SS, Zhong CY, Han HY
Nutrients 2017 Jun 3;9(6)
Nutrients 2017 Jun 3;9(6)
Linc-DYNC2H1-4 promotes EMT and CSC phenotypes by acting as a sponge of miR-145 in pancreatic cancer cells.
Gao Y, Zhang Z, Li K, Gong L, Yang Q, Huang X, Hong C, Ding M, Yang H
Cell death & disease 2017 Jul 13;8(7):e2924
Cell death & disease 2017 Jul 13;8(7):e2924
Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells.
Zhu J, Jiang Y, Yang X, Wang S, Xie C, Li X, Li Y, Chen Y, Wang X, Meng Y, Zhu M, Wu R, Huang C, Ma X, Geng S, Wu J, Zhong C
Biochemical and biophysical research communications 2017 Jan 1;482(1):15-21
Biochemical and biophysical research communications 2017 Jan 1;482(1):15-21
Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.
Zhu JY, Yang X, Chen Y, Jiang Y, Wang SJ, Li Y, Wang XQ, Meng Y, Zhu MM, Ma X, Huang C, Wu R, Xie CF, Li XT, Geng SS, Wu JS, Zhong CY, Han HY
Phytotherapy research : PTR 2017 Apr;31(4):680-688
Phytotherapy research : PTR 2017 Apr;31(4):680-688
Small-Activating RNA Can Change Nucleosome Positioning in Human Fibroblasts.
Wang B, Sun J, Shi J, Guo Q, Tong X, Zhang J, Hu N, Hu Y
Journal of biomolecular screening 2016 Jul;21(6):634-42
Journal of biomolecular screening 2016 Jul;21(6):634-42
The endoplasmic reticulum-mitochondria interface is perturbed in PARK2 knockout mice and patients with PARK2 mutations.
Gautier CA, Erpapazoglou Z, Mouton-Liger F, Muriel MP, Cormier F, Bigou S, Duffaure S, Girard M, Foret B, Iannielli A, Broccoli V, Dalle C, Bohl D, Michel PP, Corvol JC, Brice A, Corti O
Human molecular genetics 2016 Jul 15;25(14):2972-2984
Human molecular genetics 2016 Jul 15;25(14):2972-2984
ROCK inhibitor Y27632 promotes proliferation and diminishes apoptosis of marmoset induced pluripotent stem cells by suppressing expression and activity of caspase 3.
Wu Y, Shu J, He C, Li M, Wang Y, Ou W, He Y
Theriogenology 2016 Jan 15;85(2):302-14
Theriogenology 2016 Jan 15;85(2):302-14
MicroRNA-490-3P targets CDK1 and inhibits ovarian epithelial carcinoma tumorigenesis and progression.
Chen S, Chen X, Xiu YL, Sun KX, Zhao Y
Cancer letters 2015 Jun 28;362(1):122-30
Cancer letters 2015 Jun 28;362(1):122-30
Loss of SNAIL regulated miR-128-2 on chromosome 3p22.3 targets multiple stem cell factors to promote transformation of mammary epithelial cells.
Qian P, Banerjee A, Wu ZS, Zhang X, Wang H, Pandey V, Zhang WJ, Lv XF, Tan S, Lobie PE, Zhu T
Cancer research 2012 Nov 15;72(22):6036-50
Cancer research 2012 Nov 15;72(22):6036-50
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- rat brain tissue were subjected to SDS PAGE followed by western blot with 14295-1-AP( NANOG Antibody) at dilution of 1:2000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Confocal immunofluorescent analysis of human embronic stem cells with 14295-1-AP at dilution of 1:200. The PE shows staining with 14295-1-AP/PE. The DAPI shows nuclear staining by DAPI.
- Sample type
- cell line