Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [2]
- Flow cytometry [2]
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- Product number
- ABIN152020 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Nanog Homeobox (NANOG) (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 100 μL
- Storage
- Store at 4°C. Do not freeze.
- Handling
- Do not freeze.
Submitted references Chemotherapy-Induced Ca2+ Release Stimulates Breast Cancer Stem Cell Enrichment.
Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells.
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m⁶A-demethylation of NANOG mRNA.
Chemotherapy triggers HIF-1-dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype.
Reprogramming to pluripotency can conceal somatic cell chromosomal instability.
SUMOylation represses Nanog expression via modulating transcription factors Oct4 and Sox2.
Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion.
Ribosomal stress induces L11- and p53-dependent apoptosis in mouse pluripotent stem cells.
NANOG induction of fetal liver kinase-1 (FLK1) transcription regulates endothelial cell proliferation and angiogenesis.
Reprogramming of murine and human somatic cells using a single polycistronic vector.
Lu H, Chen I, Shimoda LA, Park Y, Zhang C, Tran L, Zhang H, Semenza GL
Cell reports 2017 Feb 21;18(8):1946-1957
Cell reports 2017 Feb 21;18(8):1946-1957
Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells.
Zhang C, Zhi WI, Lu H, Samanta D, Chen I, Gabrielson E, Semenza GL
Oncotarget 2016 Oct 4;7(40):64527-64542
Oncotarget 2016 Oct 4;7(40):64527-64542
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m⁶A-demethylation of NANOG mRNA.
Zhang C, Samanta D, Lu H, Bullen JW, Zhang H, Chen I, He X, Semenza GL
Proceedings of the National Academy of Sciences of the United States of America 2016 Apr 5;113(14):E2047-56
Proceedings of the National Academy of Sciences of the United States of America 2016 Apr 5;113(14):E2047-56
Chemotherapy triggers HIF-1-dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype.
Lu H, Samanta D, Xiang L, Zhang H, Hu H, Chen I, Bullen JW, Semenza GL
Proceedings of the National Academy of Sciences of the United States of America 2015 Aug 18;112(33):E4600-9
Proceedings of the National Academy of Sciences of the United States of America 2015 Aug 18;112(33):E4600-9
Reprogramming to pluripotency can conceal somatic cell chromosomal instability.
Hamada M, Malureanu LA, Wijshake T, Zhou W, van Deursen JM
PLoS genetics 2012;8(8):e1002913
PLoS genetics 2012;8(8):e1002913
SUMOylation represses Nanog expression via modulating transcription factors Oct4 and Sox2.
Wu Y, Guo Z, Wu H, Wang X, Yang L, Shi X, Du J, Tang B, Li W, Yang L, Zhang Y
PloS one 2012;7(6):e39606
PloS one 2012;7(6):e39606
Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion.
Ganuza M, Sáiz-Ladera C, Cañamero M, Gómez G, Schneider R, Blasco MA, Pisano D, Paramio JM, Santamaría D, Barbacid M
The EMBO journal 2012 May 30;31(11):2498-510
The EMBO journal 2012 May 30;31(11):2498-510
Ribosomal stress induces L11- and p53-dependent apoptosis in mouse pluripotent stem cells.
Morgado-Palacin L, Llanos S, Serrano M
Cell cycle (Georgetown, Tex.) 2012 Feb 1;11(3):503-10
Cell cycle (Georgetown, Tex.) 2012 Feb 1;11(3):503-10
NANOG induction of fetal liver kinase-1 (FLK1) transcription regulates endothelial cell proliferation and angiogenesis.
Kohler EE, Cowan CE, Chatterjee I, Malik AB, Wary KK
Blood 2011 Feb 3;117(5):1761-9
Blood 2011 Feb 3;117(5):1761-9
Reprogramming of murine and human somatic cells using a single polycistronic vector.
Carey BW, Markoulaki S, Hanna J, Saha K, Gao Q, Mitalipova M, Jaenisch R
Proceedings of the National Academy of Sciences of the United States of America 2009 Jan 6;106(1):157-62
Proceedings of the National Academy of Sciences of the United States of America 2009 Jan 6;106(1):157-62
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Supportive validation
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