FNab03017

antibody from FineTest Biotech

Targeting: FAS APO-1, APT1, CD95, FAS1, TNFRSF6

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Immunohistochemistry

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Validation data

Product number: FNab03017 - Provider product page
Provider: FineTest Biotech
Product name: FAS/CD95 antibody
Antibody type: Monoclonal
Antigen: Recombinant protein fragment
Description: Fas(CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor(TNF) receptor superfamily. It can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex(DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The molecular mass of native Fas is 38 kDa, the high molecular weight form(40-55 kDa) of Fas is due to glycosylation.
Reactivity: Human, Mouse
Host: Mouse
Conjugate: Unconjugated
Antigen sequence: Fas(TNF receptor superfamily, membe r 6)
Epitope: IgG2a
Isotype: IgG
Antibody clone number: 4B6
Vial size: 100¦Ìg
Concentration: Protein A+G purification
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

FAS protein structure - FNab03017 shown in red.