Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Immunocytochemistry [2]
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Validation data
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- Product number
- ADI-AAM-227-E - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ADI-AAM-227-E, RRID:AB_2038981
- Product name
- Fas monoclonal antibody (ZB4)
- Antibody type
- Monoclonal
- Antigen
- Recombinant full length protein
- Description
- Protein A affinity purified.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- ZB4
- Vial size
- 100 μg
- Storage
- -20°C
Submitted references LFA-1-targeting Leukotoxin (LtxA; Leukothera®) causes lymphoma tumor regression in a humanized mouse model and requires caspase-8 and Fas to kill malignant lymphocytes.
Enhanced CD95-mediated apoptosis contributes to radiation hypersensitivity of NBS lymphoblasts.
DiFranco KM, Johnson-Farley N, Bertino JR, Elson D, Vega BA, Belinka BA Jr, Kachlany SC
Leukemia research 2015 Jun;39(6):649-56
Leukemia research 2015 Jun;39(6):649-56
Enhanced CD95-mediated apoptosis contributes to radiation hypersensitivity of NBS lymphoblasts.
Sagan D, Mörtl S, Müller I, Eckardt-Schupp F, Eichholtz-Wirth H
Apoptosis : an international journal on programmed cell death 2007 Apr;12(4):753-67
Apoptosis : an international journal on programmed cell death 2007 Apr;12(4):753-67
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Supportive validation
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Western blot analysis of human Fas expression in human Fas transfected cells; Lane1: anti-human Fas (ZB4), Lane2: anti-human Fas (UB2) and Lane3: anti-human Fas (CH11).
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Flow cytometric analysis of human Fas expression on normal human lymphocytes. Open histogram indicates the reaction of isotypic control to the cells. Shaded histogram indicates the reaction of Fas mAb (ZB4) to the cells.