Explore
Validate
LearnABIN450350
antibody from antibodies-online
Targeting: BRCA1
BRCC1, FANCS, PPP1R53, RNF53
Western blot
ELISA Immunocytochemistry Immunoprecipitation Immunohistochemistry Chromatin ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [2]
- Immunoprecipitation [3]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN450350 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Breast Cancer 1 (BRCA1) antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 17F8
- Vial size
- 100 μL
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Can soy phytoestrogens decrease DNA methylation in BRCA1 and BRCA2 oncosuppressor genes in breast cancer?
Soy phytoestrogens modify DNA methylation of GSTP1, RASSF1A, EPH2 and BRCA1 promoter in prostate cancer cells.
An hGCN5/TRRAP histone acetyltransferase complex co-activates BRCA1 transactivation function through histone modification.
Differential expressions of BRCA1 and BRCA2 in infantile gynecomastia.
BRCA1 shifts p53-mediated cellular outcomes towards irreversible growth arrest.
BRCA1 and BRCA2 protein expressions in an ovotestis of a 46, XX true hermaphrodite.
Tumor suppressor p53 is required to modulate BRCA1 expression.
Transactivation of the p21 promoter by BRCA1 splice variants in mammary epithelial cells: evidence for both common and distinct activities of wildtype and mutant forms.
ATM complexes with HDM2 and promotes its rapid phosphorylation in a p53-independent manner in normal and tumor human cells exposed to ionizing radiation.
Bosviel R, Dumollard E, Déchelotte P, Bignon YJ, Bernard-Gallon D
Omics : a journal of integrative biology 2012 May;16(5):235-44
Omics : a journal of integrative biology 2012 May;16(5):235-44
Soy phytoestrogens modify DNA methylation of GSTP1, RASSF1A, EPH2 and BRCA1 promoter in prostate cancer cells.
Vardi A, Bosviel R, Rabiau N, Adjakly M, Satih S, Dechelotte P, Boiteux JP, Fontana L, Bignon YJ, Guy L, Bernard-Gallon DJ
In vivo (Athens, Greece) 2010 Jul-Aug;24(4):393-400
In vivo (Athens, Greece) 2010 Jul-Aug;24(4):393-400
An hGCN5/TRRAP histone acetyltransferase complex co-activates BRCA1 transactivation function through histone modification.
Oishi H, Kitagawa H, Wada O, Takezawa S, Tora L, Kouzu-Fujita M, Takada I, Yano T, Yanagisawa J, Kato S
The Journal of biological chemistry 2006 Jan 6;281(1):20-6
The Journal of biological chemistry 2006 Jan 6;281(1):20-6
Differential expressions of BRCA1 and BRCA2 in infantile gynecomastia.
Bernard-Gallon DJ, Dechelotte PJ, Le Corre L, Chalabi N, Vissac-Sabatier C, Bignon YJ
Anticancer research 2004 Jan-Feb;24(1):321-4
Anticancer research 2004 Jan-Feb;24(1):321-4
BRCA1 shifts p53-mediated cellular outcomes towards irreversible growth arrest.
Ongusaha PP, Ouchi T, Kim KT, Nytko E, Kwak JC, Duda RB, Deng CX, Lee SW
Oncogene 2003 Jun 12;22(24):3749-58
Oncogene 2003 Jun 12;22(24):3749-58
BRCA1 and BRCA2 protein expressions in an ovotestis of a 46, XX true hermaphrodite.
Bernard-Gallon DJ, Déchelotte P, Vissac C, Aunoble B, Cravello L, Malpuech G, Bignon YJ
Breast cancer research : BCR 2001;3(1):61-5
Breast cancer research : BCR 2001;3(1):61-5
Tumor suppressor p53 is required to modulate BRCA1 expression.
Arizti P, Fang L, Park I, Yin Y, Solomon E, Ouchi T, Aaronson SA, Lee SW
Molecular and cellular biology 2000 Oct;20(20):7450-9
Molecular and cellular biology 2000 Oct;20(20):7450-9
Transactivation of the p21 promoter by BRCA1 splice variants in mammary epithelial cells: evidence for both common and distinct activities of wildtype and mutant forms.
Lu M, Arrick BA
Oncogene 2000 Dec 14;19(54):6351-60
Oncogene 2000 Dec 14;19(54):6351-60
ATM complexes with HDM2 and promotes its rapid phosphorylation in a p53-independent manner in normal and tumor human cells exposed to ionizing radiation.
de Toledo SM, Azzam EI, Dahlberg WK, Gooding TB, Little JB
Oncogene 2000 Dec 14;19(54):6185-93
Oncogene 2000 Dec 14;19(54):6185-93
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IP
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IP
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IP
