FNab06743

antibody from FineTest Biotech

Targeting: PQBP1 MRX2, MRX55, MRXS3, MRXS8, RENS1, SHS

Western blot

ELISA

Antibody data

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Validation data

Product number: FNab06743 - Provider product page
Provider: FineTest Biotech
Product name: PQBP1 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Probably functions as scaffold protein that is part of numerous complexes and thereby plays a role in pre-mRNA splicing, transcription regulation and neuron development. Required for normal alternative splicing of target pre-mRNA species(PubMed:23512658). May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: polyglutamine binding protein 1
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

PQBP1 protein structure - FNab06743 shown in red.