BS6412

antibody from Bioworld Technology, Inc
Targeting: RAC1 p21-Rac1, Rac-1, TC-25
Provider product page for BS6412
Western blot
Immunohistochemistry

Antibody data

Product number
BS6412 - Provider product page
Provider
Bioworld Technology, Inc
Product name
RAC1 (phospho S71) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human RAC1 around the phosphorylation site of Serine 71.
Description
A large number of low molecular weight GTP-binding proteins of the Ras superfamily have been identified in eukaryotic cells; they regulate many fundamental processes such as cell growth, vesicle traffic and cytoskeletal organization. GTPase-activating proteins accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in downregulation of their active form. Rac 1 is activated in a type I interferon (IFN) dependent manner; its function is required for downstream engagement of the p38 MAP kinase pathway. The p38 MAP kinase plays an essential role in IFN-dependent transcriptional regulation. The serine/threonine kinase Akt, of the phospho-inositide 3-kinase signal transduction pathway phosphorylates serine 71 of Rac 1.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
RAC1 protein structure - BS6412 shown in red.