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- Antibody Data
- Antigen structure
- References [3]
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- Product number
- PB9431 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-Rac1 Antibody Picoband™
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for RAC1 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB, ICC/IF. Reactive species: Human. RAC1 information: Molecular Weight: 21450 MW; Subcellular Localization: Cell membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome . Cytoplasm . Inner surface of plasma membrane possibly with attachment requiring prenylation of the C-terminal cysteine (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Found in the ruffled border (a late endosomal-like compartment in the plasma membrane) of bone-resorbing osteoclasts (By similarity); Tissue Specificity: Isoform B is predominantly identified in skin and epithelial tissues from the intestinal tract. Its expression is elevated in colorectal tumors at various stages of neoplastic progression, as compared to their respective adjacent tissues.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references Chronic asthma-induced behavioral and hippocampal neuronal morphological changes are concurrent with BDNF, cofilin1 and Cdc42/RhoA alterations in immature mice.
Novel derivative of Paeonol, Paeononlsilatie sodium, alleviates behavioral damage and hippocampal dendritic injury in Alzheimer's disease concurrent with cofilin1/phosphorylated-cofilin1 and RAC1/CDC42 alterations in rats.
Gadolinium promoted proliferation in mouse embryo fibroblast NIH3T3 cells through Rac and PI3K/Akt signaling pathways.
Zhuang TT, Pan C, Chen JJ, Han F, Zhu XL, Xu H, Lu YP
Brain research bulletin 2018 Oct;143:194-206
Brain research bulletin 2018 Oct;143:194-206
Novel derivative of Paeonol, Paeononlsilatie sodium, alleviates behavioral damage and hippocampal dendritic injury in Alzheimer's disease concurrent with cofilin1/phosphorylated-cofilin1 and RAC1/CDC42 alterations in rats.
Han F, Zhuang TT, Chen JJ, Zhu XL, Cai YF, Lu YP
PloS one 2017;12(9):e0185102
PloS one 2017;12(9):e0185102
Gadolinium promoted proliferation in mouse embryo fibroblast NIH3T3 cells through Rac and PI3K/Akt signaling pathways.
Shen L, Yang A, Yao P, Sun X, Chen C, Mo C, Shi L, Chen Y, Liu Q
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2014 Aug;27(4):753-62
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2014 Aug;27(4):753-62
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- Anti- RAC1 Picoband antibody, PB9431, Western blottingAll lanes: Anti RAC1 (PB9431) at 0.5ug/mlLane 1: Rat Pancreas Tissue Lysate at 50ugLane 2: Mouse Intestine Tissue Lysate at 50ugLane 3: HELA Whole Cell Lysate at 40ugLane 4: COLO320 Whole Cell Lysate at 40ugLane 5: SGC Whole Cell Lysate at 40ugPredicted bind size: 21KDObserved bind size: 21KD
- Additional image
