Explore
Validate
LearnPAB11277
antibody from Abnova Corporation
Targeting: THRB
ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- PAB11277 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB11277, RRID:AB_1710453
- Product name
- THRB polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of THRB.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function.
Pituitary resistance to thyroid hormone syndrome is associated with T3 receptor mutants that selectively impair beta2 isoform function.
Physiological and molecular basis of thyroid hormone action.
Nascimento AS, Dias SM, Nunes FM, AparÃcio R, Ambrosio AL, Bleicher L, Figueira AC, Santos MA, de Oliveira Neto M, Fischer H, Togashi M, Craievich AF, Garratt RC, Baxter JD, Webb P, Polikarpov I
Journal of molecular biology 2006 Jul 14;360(3):586-98
Journal of molecular biology 2006 Jul 14;360(3):586-98
Pituitary resistance to thyroid hormone syndrome is associated with T3 receptor mutants that selectively impair beta2 isoform function.
Wan W, Farboud B, Privalsky ML
Molecular endocrinology (Baltimore, Md.) 2005 Jun;19(6):1529-42
Molecular endocrinology (Baltimore, Md.) 2005 Jun;19(6):1529-42
Physiological and molecular basis of thyroid hormone action.
Yen PM
Physiological reviews 2001 Jul;81(3):1097-142
Physiological reviews 2001 Jul;81(3):1097-142
No comments: Submit comment
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot using THRB polyclonal antibody (Cat # PAB11277) shows detection of in vitro translated THRB (lane 2) and human thyroid stable cell line expressing THTRB (lane 3).No staining is evident in non transfected human thyroid cells (lane 1), over expressed THRA (lane 4) or HeLa stable cell line expressing THRA (lane 5).The band at ~62 kDa, indicated by the arrowheads, corresponds to THRB.Personal communication, H. Ying, NCI, Bethesda, MD.
