Ab111533

antibody from Aladdin Scientific

Targeting: MAPK9 JNK2, p54a, PRKM9, SAPK

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Product number: Ab111533 - Provider product page
Provider: Aladdin Scientific
Product name: Recombinant JNK2 Antibody
Antibody type: Recombinant
Description: Rabbit anti Human JNK2 Antibody, Recombinant, could be used for WB, IHC and so on.Application:WB: 1/500-1/1000 IHC: 1/50-1/100FunctionResponds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. JNK2 isoforms display different binding patterns: alpha-1 and alpha-2 preferentially bind to c-Jun, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms. JUNB is not a substrate for JNK2 alpha-2, and JUND binds only weakly to it.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: AA 361-374
Vial size: 100_l,10_l,1ml,50_l
Concentration: 0,3 mg/ml
Storage: Store at 4¡C short term (1-2 weeks). Store at -20¡C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

MAPK9 protein structure - Ab111533 shown in red.