Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 844702 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#844702, RRID:AB_2565806
- Product name
- Purified anti-CD325 (N-Cadherin)
- Antibody type
- Monoclonal
- Antigen
- Human N-cadherin cytoplasmic domain fused to recombinant MBP.
- Description
- CD325 (N-cadherin) is important for neuronal migration during development, neurite outgrowth and target finding during differentiation, initial formation of synapses, and synaptic plasticity in mature neurons. CD325 (N-cadherin) is a 130 kD single pass transmembrane protein. Its extracellular region consists of five extracellular cadherin domains and has one cytoplasmic domain. N-cadherin is involved in organogenesis and in the maintenance of organ architecture by contributing to the sorting of heterogeneous cell types and in the cell adhesion needed to form tissues. N-cadherin is expressed by stem cells, myeloblasts, endothelial cells, fibroblasts, and also is expressed in neural and muscle tissues along with some types of carcinoma cells. CD325 associates with the cytoskeleton trough catenin proteins.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- 13A9
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Western blot was incubated with either clone 13A9 (lanes 1-2) or mouse IgG1 isotype control (lanes 3-4) at 10 µg/ml. Lanes 1&3: Molecular weight markers. Lanes 2&4: 10 µg rat whole brain lysate.
- Conjugate
- Unconjugated