BS7411

antibody from Bioworld Technology, Inc
Targeting: TAPBP TAPA
Provider product page for BS7411
Western blot
Immunohistochemistry

Antibody data

Product number
BS7411 - Provider product page
Provider
Bioworld Technology, Inc
Product name
TAPBP polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human TAPBP.
Description
This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
TAPBP protein structure - BS7411 shown in red.