PAB12631
antibody from Abnova Corporation
Targeting: LRP5
BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2
Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Other assay [1]
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Validation data
Reference
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- Product number
- PAB12631 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB12631, RRID:AB_10562169
- Product name
- LRP5 (phospho T1492) polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of LRP5.
- Storage
- Store at 4°C. For long term storage store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Astragaloside IV inhibits the up-regulation of Wnt/β-catenin signaling in rats with unilateral ureteral obstruction.
Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction.
Wang L, Chi YF, Yuan ZT, Zhou WC, Yin PH, Zhang XM, Peng W
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2014;33(5):1316-28
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2014;33(5):1316-28
Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction.
Davidson G, Wu W, Shen J, Bilic J, Fenger U, Stannek P, Glinka A, Niehrs C
Nature 2005 Dec 8;438(7069):867-72
Nature 2005 Dec 8;438(7069):867-72
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The cell lysate derived from conditioned LRP5 transfected HEK293 was immunoprobed by LRP5 (phospho T1492) polyclonal antibody (Cat # PAB12631) at 1:500 dilution. An immunoreactive band is observed around ~175kDa (lane 1). This band is abolished by pre-incubation with immunizing peptide (lane 2).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- 1 µg peptide was blot onto NC membrane (A: LRP5 (pT1492); B: LRP5 (non-phospho); C: Non-related phosphopeptide) was blotted by LRP5 (phospho T1492) polyclonal antibody (Cat # PAB12631) at 1:2000 dilution.
- Validation comment
- Dot Blot (Peptide)