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Learn12929-2-AP
antibody from Proteintech Group
Targeting: SRSF1
ASF, MGC5228, SF2, SF2p33, SFRS1, SRp30a
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 12929-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12929-2-AP, RRID:AB_2187211
- Product name
- ASF/SF2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ASF/SF2 antibody (Cat. #12929-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The long non-coding RNA PFI protects against pulmonary fibrosis by interacting with splicing regulator SRSF1.
SRSF protein kinase 1 modulates RAN translation and suppresses CGG repeat toxicity.
Extracellular matrix stiffness controls VEGF165 secretion and neuroblastoma angiogenesis via the YAP/RUNX2/SRSF1 axis.
Sequence-dependent recruitment of SRSF1 and SRSF7 to intronless lncRNA NKILA promotes nuclear export via the TREX/TAP pathway.
The SRSF1/circATP5B/miR-185-5p/HOXB5 feedback loop regulates the proliferation of glioma stem cells via the IL6-mediated JAK2/STAT3 signaling pathway.
LncRNA HOTAIR aggravates myocardial ischemia-reperfusion injury by sponging microRNA-126 to upregulate SRSF1.
CD63+ Cancer-Associated Fibroblasts Confer Tamoxifen Resistance to Breast Cancer Cells through Exosomal miR-22.
CircFOXK2 Promotes Growth and Metastasis of Pancreatic Ductal Adenocarcinoma by Complexing with RNA-Binding Proteins and Sponging MiR-942.
Long noncoding RNA HOXA11-AS promotes gastric cancer cell proliferation and invasion via SRSF1 and functions as a biomarker in gastric cancer.
SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating LRP8 and ApoE.
Defensive effect of microRNA-200b/c against amyloid-beta peptide-induced toxicity in Alzheimer's disease models.
Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal.
Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growth.
PP1γ functionally augments the alternative splicing of CaMKIIδ through interaction with ASF.
Rescue of cardiac failing and remodelling by inhibition of protein phosphatase 1γ is associated with suppression of the alternative splicing factor-mediated splicing of Ca2+/calmodulin-dependent protein kinase δ.
Sun J, Jin T, Su W, Guo Y, Niu Z, Guo J, Li L, Wang J, Ma L, Yu T, Li X, Zhou Y, Shan H, Liang H
Cell death and differentiation 2021 Oct;28(10):2916-2930
Cell death and differentiation 2021 Oct;28(10):2916-2930
SRSF protein kinase 1 modulates RAN translation and suppresses CGG repeat toxicity.
Malik I, Tseng YJ, Wright SE, Zheng K, Ramaiyer P, Green KM, Todd PK
EMBO molecular medicine 2021 Nov 8;13(11):e14163
EMBO molecular medicine 2021 Nov 8;13(11):e14163
Extracellular matrix stiffness controls VEGF165 secretion and neuroblastoma angiogenesis via the YAP/RUNX2/SRSF1 axis.
Bao M, Chen Y, Liu JT, Bao H, Wang WB, Qi YX, Lv F
Angiogenesis 2021 Jun 25;
Angiogenesis 2021 Jun 25;
Sequence-dependent recruitment of SRSF1 and SRSF7 to intronless lncRNA NKILA promotes nuclear export via the TREX/TAP pathway.
Khan M, Hou S, Azam S, Lei H
Nucleic acids research 2021 Jun 21;49(11):6420-6436
Nucleic acids research 2021 Jun 21;49(11):6420-6436
The SRSF1/circATP5B/miR-185-5p/HOXB5 feedback loop regulates the proliferation of glioma stem cells via the IL6-mediated JAK2/STAT3 signaling pathway.
Zhao J, Jiang Y, Zhang H, Zhou J, Chen L, Li H, Xu J, Zhang G, Jing Z
Journal of experimental & clinical cancer research : CR 2021 Apr 15;40(1):134
Journal of experimental & clinical cancer research : CR 2021 Apr 15;40(1):134
LncRNA HOTAIR aggravates myocardial ischemia-reperfusion injury by sponging microRNA-126 to upregulate SRSF1.
Sun Y, Hu ZQ
European review for medical and pharmacological sciences 2020 Sep;24(17):9046-9054
European review for medical and pharmacological sciences 2020 Sep;24(17):9046-9054
CD63+ Cancer-Associated Fibroblasts Confer Tamoxifen Resistance to Breast Cancer Cells through Exosomal miR-22.
Gao Y, Li X, Zeng C, Liu C, Hao Q, Li W, Zhang K, Zhang W, Wang S, Zhao H, Fan D, Li M, Zhang Y, Zhang W, Zhang C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Nov;7(21):2002518
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Nov;7(21):2002518
CircFOXK2 Promotes Growth and Metastasis of Pancreatic Ductal Adenocarcinoma by Complexing with RNA-Binding Proteins and Sponging MiR-942.
Wong CH, Lou UK, Li Y, Chan SL, Tong JH, To KF, Chen Y
Cancer research 2020 Jun 1;80(11):2138-2149
Cancer research 2020 Jun 1;80(11):2138-2149
Long noncoding RNA HOXA11-AS promotes gastric cancer cell proliferation and invasion via SRSF1 and functions as a biomarker in gastric cancer.
Liu Y, Zhang YM, Ma FB, Pan SR, Liu BZ
World journal of gastroenterology 2019 Jun 14;25(22):2763-2775
World journal of gastroenterology 2019 Jun 14;25(22):2763-2775
SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating LRP8 and ApoE.
Raihan O, Brishti A, Li Q, Zhang Q, Li D, Li X, Zhang Q, Xie Z, Li J, Zhang J, Liu Q
Cell reports 2019 Jul 2;28(1):78-90.e6
Cell reports 2019 Jul 2;28(1):78-90.e6
Defensive effect of microRNA-200b/c against amyloid-beta peptide-induced toxicity in Alzheimer's disease models.
Higaki S, Muramatsu M, Matsuda A, Matsumoto K, Satoh JI, Michikawa M, Niida S
PloS one 2018;13(5):e0196929
PloS one 2018;13(5):e0196929
Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal.
Wen J, Lv R, Ma H, Shen H, He C, Wang J, Jiao F, Liu H, Yang P, Tan L, Lan F, Shi YG, He C, Shi Y, Diao J
Molecular cell 2018 Mar 15;69(6):1028-1038.e6
Molecular cell 2018 Mar 15;69(6):1028-1038.e6
Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growth.
Chen Y, Huang Q, Liu W, Zhu Q, Cui CP, Xu L, Guo X, Wang P, Liu J, Dong G, Wei W, Liu CH, Feng Z, He F, Zhang L
Nature communications 2018 Jun 25;9(1):2464
Nature communications 2018 Jun 25;9(1):2464
PP1γ functionally augments the alternative splicing of CaMKIIδ through interaction with ASF.
Huang C, Cao W, Liao R, Wang J, Wang Y, Tong L, Chen X, Zhu W, Zhang W
American journal of physiology. Cell physiology 2014 Jan 15;306(2):C167-77
American journal of physiology. Cell physiology 2014 Jan 15;306(2):C167-77
Rescue of cardiac failing and remodelling by inhibition of protein phosphatase 1γ is associated with suppression of the alternative splicing factor-mediated splicing of Ca2+/calmodulin-dependent protein kinase δ.
Liao RJ, Tong LJ, Huang C, Cao WW, Wang YZ, Wang J, Chen XF, Zhu WZ, Zhang W
Clinical and experimental pharmacology & physiology 2014 Dec;41(12):976-85
Clinical and experimental pharmacology & physiology 2014 Dec;41(12):976-85
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ASF/SF2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ASF/SF2. This antibody recognizes human,mouse,rat antigen. The ASF/SF2 antibody has been validated for the following applications: ELISA, WB analysis.
