BS3443

antibody from Bioworld Technology, Inc
Targeting: GJB2 CX26, DFNA3, DFNB1, NSRD1
Provider product page for BS3443

Antibody data

Product number
BS3443 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Connexin 26 (H94) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 60-110 of Human Connexin 26.
Description
Each of the approximately 20 connexin isoforms produces channels with distinct permeabilities and electrical and chemical sensitivities; therefore, one connexin usually cannot fully substitute for another. Consequently, a wide variety of malignant phenotypes associate with decreased connexin expression and gap junction communication, dependent on the particular connexin that is effected. For instance, approximately half the cases of autosomal recessive non-syndromic hearing loss and a significant proportion of sporadic hearing loss can be linked to mutation in the gene encoding connexin 26.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
GJB2 protein structure - BS3443 shown in red.