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- Antibody Data
- Antigen structure
- References [26]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 11122-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11122-1-AP, RRID:AB_2059368
- Product name
- ATG12 antibody
- Antibody type
- Polyclonal
- Description
- ATG12 antibody (Cat. #11122-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS.
Hepatoprotective effects of ginsenoside Rk3 in acetaminophen-induced liver injury in mice by activation of autophagy.
Metformin sensitises hepatocarcinoma cells to methotrexate by targeting dihydrofolate reductase.
Chloroquine enhances catalpol's ability to promote apoptosis by inhibiting catalpol's autophagy-promoting effect on gastric cancer.
MEHP induces pyroptosis and autophagy alternation by cathepsin B activation in INS-1 cells.
6-Shogaol from ginger shows anti-tumor effect in cervical carcinoma via PI3K/Akt/mTOR pathway.
LncRNA CCAT1 Upregulates ATG5 to Enhance Autophagy and Promote Gastric Cancer Development by Absorbing miR-140-3p.
Resveratrol promotes osteoblastic differentiation in a rat model of postmenopausal osteoporosis by regulating autophagy.
The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis.
Galangin Protects against Symptoms of Dextran Sodium Sulfate-induced Acute Colitis by Activating Autophagy and Modulating the Gut Microbiota.
The Preparation of Ginsenoside Rg5, Its Antitumor Activity against Breast Cancer Cells and Its Targeting of PI3K.
Latcripin-7A, derivative of Lentinula edodes C91-3, reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G1 phase in breast cancer cells.
miR-30a-3p inhibits renal cancer cell invasion and metastasis through targeting ATG12.
Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer.
Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy.
LP1 from Lentinula edodes C91-3 Induces Autophagy, Apoptosis and Reduces Metastasis in Human Gastric Cancer Cell Line SGC-7901.
Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.
7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway.
The gastric mucosal protective effects of astragaloside IV in mnng-induced GPL rats.
Down-regulated miR-23a Contributes to the Metastasis of Cutaneous Melanoma by Promoting Autophagy.
Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.
The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma.
Anti-osteoclastogenesis of Mineral Trioxide Aggregate through Inhibition of the Autophagic Pathway.
Quinones Derived from Polychlorinated Biphenyls Induce ROS-Dependent Autophagy by Evoking an Autophagic Flux and Inhibition of mTOR/p70S6k.
Low doses of single or combined agrichemicals induces α-synuclein aggregation in nigrostriatal system of mice through inhibition of proteasomal and autophagic pathways.
AMPK-Dependent Phosphorylation of GAPDH Triggers Sirt1 Activation and Is Necessary for Autophagy upon Glucose Starvation.
Shang Y, Wang Q, Li J, Liu H, Zhao Q, Huang X, Dong H, Chen W, Gui R, Nie X
Frontiers in chemistry 2021;9:522708
Frontiers in chemistry 2021;9:522708
Hepatoprotective effects of ginsenoside Rk3 in acetaminophen-induced liver injury in mice by activation of autophagy.
Qu L, Fu R, Ma X, Fan D
Food & function 2021 Oct 4;12(19):9128-9140
Food & function 2021 Oct 4;12(19):9128-9140
Metformin sensitises hepatocarcinoma cells to methotrexate by targeting dihydrofolate reductase.
Wang Y, Lu H, Sun L, Chen X, Wei H, Suo C, Feng J, Yuan M, Shen S, Jia W, Wang Y, Zhang H, Li Z, Zhong X, Gao P
Cell death & disease 2021 Oct 2;12(10):902
Cell death & disease 2021 Oct 2;12(10):902
Chloroquine enhances catalpol's ability to promote apoptosis by inhibiting catalpol's autophagy-promoting effect on gastric cancer.
Sun F, Wang Z, Wang X
Journal of B.U.ON. : official journal of the Balkan Union of Oncology 2021 May-Jun;26(3):924-931
Journal of B.U.ON. : official journal of the Balkan Union of Oncology 2021 May-Jun;26(3):924-931
MEHP induces pyroptosis and autophagy alternation by cathepsin B activation in INS-1 cells.
Jiang L, Qiu T, Yao X, Chen H, Yao K, Sun X, Yang G, Jiang L, Zhang C, Wang N, Zhang H, Liu X
Environmental science and pollution research international 2021 Dec;28(47):66628-66642
Environmental science and pollution research international 2021 Dec;28(47):66628-66642
6-Shogaol from ginger shows anti-tumor effect in cervical carcinoma via PI3K/Akt/mTOR pathway.
Pei XD, He ZL, Yao HL, Xiao JS, Li L, Gu JZ, Shi PZ, Wang JH, Jiang LH
European journal of nutrition 2021 Aug;60(5):2781-2793
European journal of nutrition 2021 Aug;60(5):2781-2793
LncRNA CCAT1 Upregulates ATG5 to Enhance Autophagy and Promote Gastric Cancer Development by Absorbing miR-140-3p.
Yang F, Peng ZX, Ji WD, Yu JD, Qian C, Liu JD, Fang GE
Digestive diseases and sciences 2021 Aug 21;
Digestive diseases and sciences 2021 Aug 21;
Resveratrol promotes osteoblastic differentiation in a rat model of postmenopausal osteoporosis by regulating autophagy.
Wang W, Zhang LM, Guo C, Han JF
Nutrition & metabolism 2020;17:29
Nutrition & metabolism 2020;17:29
The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis.
Shang Y, Wang Q, Li J, Zhao Q, Huang X, Dong H, Liu H, Zhang Y, Zhang J, Gui R, Nie X
OncoTargets and therapy 2020;13:473-486
OncoTargets and therapy 2020;13:473-486
Galangin Protects against Symptoms of Dextran Sodium Sulfate-induced Acute Colitis by Activating Autophagy and Modulating the Gut Microbiota.
Xuan H, Ou A, Hao S, Shi J, Jin X
Nutrients 2020 Jan 29;12(2)
Nutrients 2020 Jan 29;12(2)
The Preparation of Ginsenoside Rg5, Its Antitumor Activity against Breast Cancer Cells and Its Targeting of PI3K.
Liu Y, Fan D
Nutrients 2020 Jan 18;12(1)
Nutrients 2020 Jan 18;12(1)
Latcripin-7A, derivative of Lentinula edodes C91-3, reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G1 phase in breast cancer cells.
Din SRU, Zhong M, Nisar MA, Saleem MZ, Hussain A, Khinsar KH, Alam S, Ayub G, Kanwal S, Li X, Zhang W, Wang X, Ning A, Cao J, Huang M
Applied microbiology and biotechnology 2020 Dec;104(23):10165-10179
Applied microbiology and biotechnology 2020 Dec;104(23):10165-10179
miR-30a-3p inhibits renal cancer cell invasion and metastasis through targeting ATG12.
Chen Y, Zhou J, Wu X, Huang J, Chen W, Liu D, Zhang J, Huang Y, Xue W
Translational andrology and urology 2020 Apr;9(2):646-653
Translational andrology and urology 2020 Apr;9(2):646-653
Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer.
Liu Y, Fan D
Biochemical pharmacology 2019 Oct;168:285-304
Biochemical pharmacology 2019 Oct;168:285-304
Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy.
Cai Q, Wang S, Jin L, Weng M, Zhou D, Wang J, Tang Z, Quan Z
Molecular cancer 2019 Apr 5;18(1):82
Molecular cancer 2019 Apr 5;18(1):82
LP1 from Lentinula edodes C91-3 Induces Autophagy, Apoptosis and Reduces Metastasis in Human Gastric Cancer Cell Line SGC-7901.
Batool S, Joseph TP, Hussain M, Vuai MS, Khinsar KH, Din SRU, Padhiar AA, Zhong M, Ning A, Zhang W, Cao J, Huang M
International journal of molecular sciences 2018 Sep 30;19(10)
International journal of molecular sciences 2018 Sep 30;19(10)
Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.
Liu Y, Fan D
Food & function 2018 Nov 14;9(11):5513-5527
Food & function 2018 Nov 14;9(11):5513-5527
7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway.
Tsai TC, Lai KH, Su JH, Wu YJ, Sheu JH
Marine drugs 2018 Mar 26;16(4)
Marine drugs 2018 Mar 26;16(4)
The gastric mucosal protective effects of astragaloside IV in mnng-induced GPL rats.
Cai T, Zhang C, Zhao Z, Li S, Cai H, Chen X, Cai D, Liu W, Yan Y, Xie K, Pan H, Zeng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:291-299
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:291-299
Down-regulated miR-23a Contributes to the Metastasis of Cutaneous Melanoma by Promoting Autophagy.
Guo W, Wang H, Yang Y, Guo S, Zhang W, Liu Y, Yi X, Ma J, Zhao T, Liu L, Jian Z, Liu L, Wang G, Gao T, Shi Q, Li C
Theranostics 2017;7(8):2231-2249
Theranostics 2017;7(8):2231-2249
Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.
Liu M, Liang K, Zhen J, Zhou M, Wang X, Wang Z, Wei X, Zhang Y, Sun Y, Zhou Z, Su H, Zhang C, Li N, Gao C, Peng J, Yi F
Nature communications 2017 Sep 4;8(1):413
Nature communications 2017 Sep 4;8(1):413
The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma.
Chen S, Wu DD, Sang XB, Wang LL, Zong ZH, Sun KX, Liu BL, Zhao Y
Cell death & disease 2017 Oct 12;8(10):e3118
Cell death & disease 2017 Oct 12;8(10):e3118
Anti-osteoclastogenesis of Mineral Trioxide Aggregate through Inhibition of the Autophagic Pathway.
Cheng X, Zhu L, Zhang J, Yu J, Liu S, Lv F, Lin Y, Liu G, Peng B
Journal of endodontics 2017 May;43(5):766-773
Journal of endodontics 2017 May;43(5):766-773
Quinones Derived from Polychlorinated Biphenyls Induce ROS-Dependent Autophagy by Evoking an Autophagic Flux and Inhibition of mTOR/p70S6k.
Shi Q, Song X, Liu Z, Wang Y, Wang Y, Fu J, Su C, Xia X, Song E, Song Y
Chemical research in toxicology 2016 Jul 18;29(7):1160-71
Chemical research in toxicology 2016 Jul 18;29(7):1160-71
Low doses of single or combined agrichemicals induces α-synuclein aggregation in nigrostriatal system of mice through inhibition of proteasomal and autophagic pathways.
Su C, Niu P
International journal of clinical and experimental medicine 2015;8(11):20508-15
International journal of clinical and experimental medicine 2015;8(11):20508-15
AMPK-Dependent Phosphorylation of GAPDH Triggers Sirt1 Activation and Is Necessary for Autophagy upon Glucose Starvation.
Chang C, Su H, Zhang D, Wang Y, Shen Q, Liu B, Huang R, Zhou T, Peng C, Wong CC, Shen HM, Lippincott-Schwartz J, Liu W
Molecular cell 2015 Dec 17;60(6):930-40
Molecular cell 2015 Dec 17;60(6):930-40
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human bladder tissue were subjected to SDS PAGE followed by western blot with 11122-1-AP(ATG12 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ATG12 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ATG12. This antibody recognizes human, mouse antigen. The ATG12 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
