Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 11697-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11697-1-AP, RRID:AB_2145604
- Product name
- MLH1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MLH1 antibody (Cat. #11697-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references C. tropicalis promotes chemotherapy resistance in colon cancer through increasing lactate production to regulate the mismatch repair system.
Lack of association of somatic CAG repeat expansion with striatal neurodegeneration in HD knock-in animal models.
Prpf31 is essential for the survival and differentiation of retinal progenitor cells by modulating alternative splicing.
Clinicopathological and survival characteristic of mismatch repair status in ovarian clear cell carcinoma.
Downregulation of GLYR1 contributes to microsatellite instability colorectal cancer by targeting p21 via the p38MAPK and PI3K/AKT pathways.
Combinatorial approach of in silico and in vitro evaluation of MLH1 variant associated with Lynch syndrome like metastatic colorectal cancer.
The testis-specific gene 1700102P08Rik is essential for male fertility.
Clinical significance of chromodomain helicase/ATPase DNA binding protein 1-like and human mutL homolog 1 gene expression in cholangiocarcinoma.
Mismatch repair status as a beneficial predictor of fluorouracil-based adjuvant chemotherapy for pancreatic cancer.
Selective tumor cell death induced by irradiated riboflavin through recognizing DNA G-T mismatch.
A highly malignant case of neuroblastoma with substantial increase of single-nucleotide variants and normal mismatch repair system: A case report.
Estradiol regulates miR-135b and mismatch repair gene expressions via estrogen receptor-β in colorectal cells.
Estrogen stimulates the expression of mismatch repair gene hMLH1 in colonic epithelial cells.
Qu J, Sun Z, Peng C, Li D, Yan W, Xu Z, Hou Y, Shen S, Chen P, Wang T
International journal of biological sciences 2021;17(11):2756-2769
International journal of biological sciences 2021;17(11):2756-2769
Lack of association of somatic CAG repeat expansion with striatal neurodegeneration in HD knock-in animal models.
Bai D, Yin P, Zhang Y, Sun F, Chen L, Lin L, Yan S, Li S, Li XJ
Human molecular genetics 2021 Jul 28;30(16):1497-1508
Human molecular genetics 2021 Jul 28;30(16):1497-1508
Prpf31 is essential for the survival and differentiation of retinal progenitor cells by modulating alternative splicing.
Li J, Liu F, Lv Y, Sun K, Zhao Y, Reilly J, Zhang Y, Tu J, Yu S, Liu X, Qin Y, Huang Y, Gao P, Jia D, Chen X, Han Y, Shu X, Luo D, Tang Z, Liu M
Nucleic acids research 2021 Feb 26;49(4):2027-2043
Nucleic acids research 2021 Feb 26;49(4):2027-2043
Clinicopathological and survival characteristic of mismatch repair status in ovarian clear cell carcinoma.
Zhu J, Ke G, Bi R, Wu X
Journal of surgical oncology 2020 Sep;122(3):538-546
Journal of surgical oncology 2020 Sep;122(3):538-546
Downregulation of GLYR1 contributes to microsatellite instability colorectal cancer by targeting p21 via the p38MAPK and PI3K/AKT pathways.
Hu Z, Long T, Ma Y, Zhu J, Gao L, Zhong Y, Wang X, Wang X, Li Z
Journal of experimental & clinical cancer research : CR 2020 May 5;39(1):76
Journal of experimental & clinical cancer research : CR 2020 May 5;39(1):76
Combinatorial approach of in silico and in vitro evaluation of MLH1 variant associated with Lynch syndrome like metastatic colorectal cancer.
Saleem K, Zaib T, Ji W, Zhang C, Qin Q, Wang Y, Xu L, Yu H, Zhu S, Dong K, Si S, Jia X, Wu J, Fu S, Sun W
Bioscience reports 2020 Jun 26;40(6)
Bioscience reports 2020 Jun 26;40(6)
The testis-specific gene 1700102P08Rik is essential for male fertility.
Wu XL, Yun DM, Gao S, Liang AJ, Duan ZZ, Wang HS, Wang GS, Sun F
Molecular reproduction and development 2020 Feb;87(2):231-240
Molecular reproduction and development 2020 Feb;87(2):231-240
Clinical significance of chromodomain helicase/ATPase DNA binding protein 1-like and human mutL homolog 1 gene expression in cholangiocarcinoma.
Hua J, Li S, Huang C
Oncology letters 2018 Sep;16(3):2989-2994
Oncology letters 2018 Sep;16(3):2989-2994
Mismatch repair status as a beneficial predictor of fluorouracil-based adjuvant chemotherapy for pancreatic cancer.
Liang D, Shi S, Liang C, Meng Q, Zhang B, Ni Q, Xu J, Yu X
Surgery 2018 May;163(5):1080-1089
Surgery 2018 May;163(5):1080-1089
Selective tumor cell death induced by irradiated riboflavin through recognizing DNA G-T mismatch.
Yuan Y, Zhao Y, Chen L, Wu J, Chen G, Li S, Zou J, Chen R, Wang J, Jiang F, Tang Z
Nucleic acids research 2017 Sep 6;45(15):8676-8683
Nucleic acids research 2017 Sep 6;45(15):8676-8683
A highly malignant case of neuroblastoma with substantial increase of single-nucleotide variants and normal mismatch repair system: A case report.
Yuan LQ, Wang JH, Zhu K, Yang M, Gu WZ, Lai C, Li HM, Shu Q, Chen X
Medicine 2017 Dec;96(50):e8845
Medicine 2017 Dec;96(50):e8845
Estradiol regulates miR-135b and mismatch repair gene expressions via estrogen receptor-β in colorectal cells.
He YQ, Sheng JQ, Ling XL, Fu L, Jin P, Yen L, Rao J
Experimental & molecular medicine 2012 Dec 31;44(12):723-32
Experimental & molecular medicine 2012 Dec 31;44(12):723-32
Estrogen stimulates the expression of mismatch repair gene hMLH1 in colonic epithelial cells.
Jin P, Lu XJ, Sheng JQ, Fu L, Meng XM, Wang X, Shi TP, Li SR, Rao J
Cancer prevention research (Philadelphia, Pa.) 2010 Aug;3(8):910-6
Cancer prevention research (Philadelphia, Pa.) 2010 Aug;3(8):910-6
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 11697-1-AP(MLH1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MLH1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MLH1. This antibody recognizes human,mouse,rat antigen. The MLH1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
