ATIC

gene product
AICARFT, IMPCHASE, PURH
This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq, Sep 2009]
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398 antibodies from 34 providers.

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Signalway Antibody LLC
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Arigo
1 antibody
BioLegend
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RayBiotech, Inc.
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Leading Biology
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1 antibody
Abgent
1 antibody