BS6973

antibody from Bioworld Technology, Inc
Targeting: ATIC AICARFT, IMPCHASE, PURH
Provider product page for BS6973
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6973 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ATIC polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human ATIC.
Description
The bifunctional purine biosynthesis protein ATIC (also designated PURH) contains AICAR transformylase and IMP cyclohydrolase activities. AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) transformylase catalyzes the second to last step in purine biosynthesis, playing an important role in the production of nucleotides and IMP. Defects in the ATIC transformylase gene can cause AICA-rebsuria, also designated AICA-ribosiduria, an inborn error in purine biosynthesis that is neurologically cataclysmic.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ATIC protein structure - BS6973 shown in red.