BS3197

antibody from Bioworld Technology, Inc

Targeting: PDLIM5 Enh, LIM

Western blot (Data presented on provider website)

Antibody Data

Product number

BS3197

Provider

Bioworld Technology, Inc

Product name

PDLIM5 (S257) polyclonal antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide, corresponding to amino acids 223-270 of Human PDLIM5.

Description

The protein encoded by the PDLIM5 (PDZ and LIM domain 5) gene is a LIM domain protein. LIM domains are cysteine rich double zinc fingers composed of 50-60 amino acids that are involved in protein-protein interactions. LIM domain containing proteins are scaffolds for the formation of multiprotein complexes. They are involved in cytoskeleton organization, where they interact with various PKC isoforms through the LIM domains and with actin and alpha actinin through the PDZ domain. In addition, they are involved in cell lineage specification, organ development, and oncogenesis. This protein is also a member of the Enigma class of proteins, a family of proteins that have a 100 amino acid PDZ domain in the N terminus and 1 to 3 LIM domains in the C terminus. Multiple transcript variants encoding different isoforms have been found for this gene, but not all of them have been fully characterized.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.